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PANDIT
Protein and Associated NucleotideDomains with Inferred Trees

PF00017 alignment
(54 sequences with 109 aa)


ZAP70_MOUSE/10-87 FFYGSISR.....AEAEEHLKLA....GMADGLFLLRQCLR.SLGG...YVLSLVHDV-.....---RFHHFPIERQLNG.......TYAIAGGKA..HCGPAELCQFY
KSYK_HUMAN/15-92 FFFGNITR.....EEAEDYLVQG....GMSDGLYLLRQSRN.YLGG...FALSVAHGR-.....---KAHHYTIERELNG.......TYAIAGGRT..HASPADLCHYH
ZAP70_HUMAN/163-239 WYHSSLTR.....EEAERKLYSG....AQTDGKFLLRPRKE.-QGT...YALSLIYGK-.....---TVYHYLISQDKAG.......KYCIPEGTK..FDTLWQLVEYL
KSYK_PIG/163-238 WFHGKISR.....DESEQIVLIG....SKTNGKFLIRARDN.--GS...YALGLLHEG-.....---KVLHYRIDKDKTG.......KLSIPGGKN..FDTLWQLVEHY
MATK_HUMAN/122-196 WFHGKISG.....QEAVQQLQP-....-PEDGLFLVRESAR.HPGD...YVLCVSFGR-.....---DVIHYRVLHRDG-.......HLTIDEAVF..FCNLMDMVEHY
CSK_CHICK/82-156 WFHGKITR.....EQAERLLYP-....-PETGLFLVRESTN.YPGD...YTLCVSCEG-.....---KVEHYRIIYSSSK.......-LSIDEEVY..FENLMQLVEHY
CRKL_HUMAN/14-88 WYMGPVSR.....QEAQTRLQG-....-QRHGMFLVRDSST.CPGD...YVLSVSENS-.....---RVSHYIINSLPNR.......-RFKIGDQE..FDHLPALLEFY
YES_XIPHE/159-241 WYFGKLSR.....KDTERLLLLP....GNERGTFLIRESET.TKGA...YSLSLRDWDE....tKGDNCKHYKIRKLDNG.......GYYITTRTQ..FMSLQMLVKHY
FGR_HUMAN/144-226 WYFGKIGR.....KDAERQLLSP....GNPQGAFLIRESET.TKGA...YSLSIRDWDQ....tRGDHVKHYKIRKLDMG.......GYYITTRVQ..FNSVQELVQHY
SRC_RSVP/148-230 WYFGKITR.....RESERLLLNP....ENPRGTFLVRKSET.AKGA...YCLSVSDFDN....aKGPNVKHYKIYKLYSG.......GFYITSRTQ..FGSLQQLVAYY
LYN_MOUSE/128-210 WFFKDITR.....KDAERQLLAP....GNSAGAFLIRESET.LKGS...FSLSVRDYDP....mHGDVIKHYKIRSLDNG.......GYYISPRIT..FPCISDMIKHY
BLK_MOUSE/117-198 WFFRTISR.....KDAERQLLAP....MNKAGSFLIRESES.NKGA...FSLSVKDITT.....QGEVVKHYKIRSLDNG.......GYYISPRIT..FPTLQALVQHY
LCK_MOUSE/126-208 WFFKNLSR.....KDAERQLLAP....GNTHGSFLIRESES.TAGS...FSLSVRDFDQ....nQGEVVKHYKIRNLDNG.......GFYISPRIT..FPGLHDLVRHY
HCK_MOUSE/141-223 WFFKGISR.....KDAERHLLAP....GNMLGSFMIRDSET.TKGS...YSLSVRDFDP....qHGDTVKHYKIRTLDSG.......GFYISPRST..FSSLQELVLHY
STK_HYDAT/126-203 WYFGDVKR.....AEAEKRLMVR....GLPSGTFLIRKAET.AVGN...FSLSVRDGD-.....---SVKHYRVRKLDTG.......GYFITTRAP..FNSLYELVQHY
SRK4_SPOLA/122-199 WFFGQVKR.....VDAEKQLMMP....FNNLGSFLIRDSDT.TPGD...FSLSVRDID-.....---RVRHYRIKKLENG.......TYFVTRRLT..FQSIQELVAYY
SRK1_SPOLA/122-199 WFLGKIKR.....VEAEKMLNQS....FNQVGSFLIRDSET.TPGD...FSLSVKDQD-.....---RVRHYRVRRLEDG.......SLFVTRRST..FQILHELVDHY
FRK_HUMAN/116-193 WFFGAIGR.....SDAEKQLLYS....ENKTGSFLIRESES.QKGE...FSLSVLDGA-.....---VVKHYRIKRLDEG.......GFFLTRRRI..FSTLNEFVSHY
SRC64_DROME/162-244 WFFENVLR.....KEADKLLLAE....ENPRGTFLVRPSEH.NPNG...YSLSVKDWED....gRGYHVKHYRIKPLDNG.......GYYIATNQT..FPSLQALVMAY
SEM5_CAEEL/60-136 WYLGKITR.....NDAEVLLKKP....TVRDGHFLVRQCES.SPGE...FSISVRFQD-.....---SVQHFKVLRDQNG.......-KYYLWAVK..FNSLNELVAYH
GRB2_CHICK/60-135 WFFGKIPR.....AKAEEMLGK-....QRHDGAFLIRESES.APGD...FSLSVKFGN-.....---DVQQFKVLRDGAG.......-KYLLWVVK..FNSLNELVDYH
DRK_DROME/60-134 WYYGRITR.....ADAEKLLSN-....-KHEGAFLIRISES.SPGD...FSLSVKCPD-.....---GVQHFKVLRDAQS.......-KFFLWVVK..FNSLNELVEYH
NCK1_HUMAN/282-356 WYYGKVTR.....HQAEMALNE-....RGHEGDFLIRDSES.SPND...FSVSLKAQG-.....---KNKHFKVQLKET-.......-VYCIGQRK..FSTMEELVEHY
P85B_BOVIN/618-692 WYVGKINR.....TQAEEMLSG-....-KRDGTFLIRESS-.QRGC...YACSVVVDG-.....---DTKHCVIYRTATG.......--FGFAEPYnlYGSLKELVLHY
ABL2_HUMAN/173-248 WYHGPVSR.....SAAEYLLSS-....-LINGSFLVRESES.SPGQ...LSISLRYEG-.....---RVYHYRINTTADG.......KVYVTAESR..FSTLAELVHHH
ABL1_CAEEL/194-269 WYHGKISR.....SDSEAILGS-....-GITGSFLVRESET.SIGQ...YTISVRHDG-.....---RVFHYRINVDNTE.......KMFITQEVK..FRTLGELVHHH
SHC1_HUMAN/488-559 WFHGKLSR.....REAEALLQL-....---NGDFLVRESTT.TPGQ...YVLTGLQSG-.....---QPKH-LLLVDPEG.......-VVRTKDHR..FESVSHLISYH
PLCG1_RAT/550-639 WFHGKLGAgrdgrHIAERLLTEYcietGAPDGSFLVRESET.FVGD...YTLSFWRNG-.....---KVQHCRIHSRQDAg....tpKFFLTDNLV..FDSLYDLITHY
PLCG2_HUMAN/532-617 WFHKKVEK....rTSAEKLLQEYcmetGGKDGTFLVRESET.FPND...YTLSFWRSG-.....---RVQHCRIRSTMEGg....tlKYYLTDNLT..FSSIYALIQHY
RASA1_HUMAN/181-256 WYHGKLDR.....TIAEERLRQ-....AGKSGSYLIRESDR.RPGS...FVLSFLSQMN.....---VVNHFRIIAMCGD.......-YYIGG-RR..FSSLSDLIGYY
CSW_DROME/6-81 WFHPTISG.....IEAEKLLQE-....QGFDGSFLARLSSS.NPGA...FTLSVRRGN-.....---EVTHIKIQNNGDF.......-FDLYGGEK..FATLPELVQYY
PTN6_MOUSE/4-79 WFHRDLSG.....PDAETLLKG-....RGVPGSFLARPSRK.NQGD...FSLSVRVDD-.....---QVTHIRIQNSGDF.......-YDLYGGEK..FATLTELVEYY
CSW_DROME/111-186 WFHGNLSG.....KEAEKLILE-....RGKNGSFLVRESQS.KPGD...FVLSVRTDD-.....---KVTHVMIRWQDKK.......-YDVGGGES..FGTLSELIDHY
PTN6_MOUSE/110-194 WYHGHISG.....GQAESLLQA-....KGEPWTFLVRESLS.QPGD...FVLSVLNDQPkagpgSPLRVTHIKVMCEGGR.......-YTVGGSET..FDSLTDLVEHF
PLCG2_RAT/646-720 WYYDRLSR.....GEAEDMLMR-....IPRDGAFLIRKREG.TD-S...YAITFRARG-.....---KVKHCRINRDGR-.......HFVLGTSAY..FESLVELVSYY
PLCG1_RAT/668-741 WYHASLTR.....AQAEHMLMR-....VPRDGAFLVRKRNE.-PNS...YAISFRAEG-.....---KIKHCRVQQEGQT.......-VMLGNSE-..FDSLVDLISYY
KIN31_CAEEL/20-101 YFHGLIQR.....EDVFQLLDN-....---NGDYVVRLSDP.KPGEprsYILSVMFNNKl...dENSSVKHFVINSVENK.......-YFVNNNMS..FNTIQQMLSHY
FES_MOUSE/458-528 WYHGAIPW.....AEVAELLT--....--HTGDFLVRESQG.KQ-E...YVLSVMWDG-.....---HPRHFIIQSLDN-.......-LYRLEGDG..FPSIPLLITHL
FER_HUMAN/460-531 WYHGAIPR.....IEAQELLK--....--KQGDFLVRESHG.KPGE...YVLSVYSDG-.....---QRRHFIIQYVDNM.......--YRFEGTG..FSNIPQLIDHH
FPS_DROME/960-1032 WFHGVLPR.....EEVVRLLNN-....---DGDFLVRETIRnEESQ...IVLSVCWNG-.....----HKHFIVQTTGEG.......-NFRFEGPP..FASIQELIMHQ
P85B_BOVIN/326-401 WYWGDISR.....EEVNEKLRD-....-TPDGTFLVRDASSkIQGE...YTLTLRKGG-.....---NNKL-IKVFHRDG.......-HYGFSEPL.tFCSVVDLITHY
TXK_HUMAN/150-231 WYHRNITR.....NQAEHLLRQ-....ESKEGAFIVRDSR-.HLGS...YTISVFMGARr...sTEAAIKHYQIKKNDSG.......QWYVAERHA..FQSIPELIWYH
TEC_MOUSE/246-329 WYCRNTNR.....SKAEQLLRT-....EDKEGGFMVRDSS-.QPGL...YTVSLYTKFGg...eGSSGFRHYHIKETATSp.....kKYYLAEKHA..FGSIPEIIEYH
BTK_HUMAN/281-362 WYSKHMTR.....SQAEQLLKQ-....EGKEGGFIVRDSS-.KAGK...YTVSVFAKSTg...dPQGVIRHYVVCSTPQS.......QYYLAEKHL..FSTIPELINYH
ITK_HUMAN/239-323 WYNKSISR.....DKAEKLLLD-....TGKEGAFMVRDSR-.TAGT...YTVSVFTKAVv..seNNPCIKHYHIKETNDNp.....kRYYVAEKYV..FDSIPLLINYH
BTKL_DROME/410-488 WYVGDMSR.....QRAESLLKQ-....GDKEGCFVVRKSS-.TKGL...YTLSLHTKVP.....-QSHVKHYHIKQNARC.......EYYLSEKHC..CETIPDLINYH
RASA1_HUMAN/351-426 WFHGKISK.....QEAYNLLMT-....VGQVCSFLVRPSDN.TPGD...YSLYFRTNE-.....---NIQRFKICPTPN-.......NQFMMGGRY..YNSIGDIIDHY
VAV_MOUSE/671-745 WYAGPMER.....AGAEGILTN-....-RSDGTYLVRQRVK.DTAE...FAISIKYNV-.....---EVKHIKIMTSEG-.......-LYRITEKK.aFRGLLELVEFY
SPK1_DUGTI/100-184 EAWREIQR.....WEAEKSLMKI....GLQKGTYIIRPSR-.KENS...YALSVRDFDEk...kKICIVKHFQIKTLQDE......kGISYSVNIR.nFPNILTLIQFY
STAT6_HUMAN/537-616 LIIGFISK.....QYVTSLLLN-....-EPDGTFLLRFSDS.EIGG...ITIAHVIRGQ....dGSPQIENIQPFSAKDL.......-SIRSLGDR..IRDLAQLKNLY
STA5A_SHEEP/589-670 WNDGAILGfv.nkQQAHDLLIN-....-KPDGTFLLRFSDS.EIGG...ITIAWKFDSP.....--DRNLWNLKPFTTRE.......GSIRSLADR..LGDLNYLIYVF
STAT4_MOUSE/570-646 WIDGYIMGf..vsKEKERLLLK-....DKMPGTFLLRFSES.HLGG...ITFTWVDQS-.....---ENGEVRFHSVEP-.......--YNKGRLS..ALAFADILRDY
STAT3_MOUSE/584-674 YIMGFISK.....-ERERAILS-....TKPPGTFLLRFSESsKEGG...VTFTWVEKDIsg.ktQIQSVEPYTKQQLNNMsfaeiimGYKIMD-AT..NILVSPLVYLY
SPT6_YEAST/1258-1339 YYFPFNGR.....-QAEDYLRS-....-KERGEFVIRQSSR.GDDH...LVITWKLDKD.....---LFQHIDIQELEKEnpl.algKVLIVDNQK..YNDLDQIIVEY