{"version":"6.9","hitCount":1,"request":{"queryString":"EXT_ID:39893137","resultType":"core","cursorMark":"*","pageSize":25,"sort":"","synonym":false},"resultList":{"result":[{"id":"39893137","source":"MED","pmid":"39893137","doi":"10.1016/j.clcc.2025.01.002","title":"The Impact of a Multidisciplinary Tumor Board (MDTB) in the Management of Colorectal Cancer (CRC).","authorString":"Schietroma F, Bensi M, Calegari MA, Pozzo C, Basso M, Valente G, Caira G, Trovato G, Spring A, Beccia V, Ceccarelli A, Perazzo S, Chiofalo L, Barbaro B, Tatulli G, Alfieri S, De Sio D, Lorenzon L, Persiani R, Lococo F, Nachira D, Giuliante F, Ardito F, Cellini F, Panza G, Cozza V, Giovinazzo F, Pafundi DP, Sofo L, Santullo F, Tondolo V, Tortora G, Salvatore L.","authorList":{"author":[{"fullName":"Schietroma F","lastName":"Schietroma","firstName":"Francesco","initials":"F","authorAffiliationDetailsList":{"authorAffiliation":[{"affiliation":"Oncologia Medica, Comprehensive Cancer Center, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy; Oncologia Medica, Università Cattolica del Sacro Cuore, Rome, Italy."}]}},{"fullName":"Bensi M","lastName":"Bensi","firstName":"Maria","initials":"M","authorAffiliationDetailsList":{"authorAffiliation":[{"affiliation":"Oncologia Medica, Comprehensive Cancer Center, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy; Oncologia Medica, Università Cattolica del Sacro Cuore, Rome, Italy."}]}},{"fullName":"Calegari MA","lastName":"Calegari","firstName":"Maria Alessandra","initials":"MA","authorAffiliationDetailsList":{"authorAffiliation":[{"affiliation":"Oncologia Medica, Comprehensive Cancer Center, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy."}]}},{"fullName":"Pozzo C","lastName":"Pozzo","firstName":"Carmelo","initials":"C","authorAffiliationDetailsList":{"authorAffiliation":[{"affiliation":"Oncologia Medica, Comprehensive Cancer Center, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy."}]}},{"fullName":"Basso M","lastName":"Basso","firstName":"Michele","initials":"M","authorAffiliationDetailsList":{"authorAffiliation":[{"affiliation":"Oncologia Medica, Comprehensive Cancer Center, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy."}]}},{"fullName":"Valente G","lastName":"Valente","firstName":"Giustina","initials":"G","authorAffiliationDetailsList":{"authorAffiliation":[{"affiliation":"Oncologia Medica, Comprehensive Cancer Center, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy; Oncologia Medica, Università Cattolica del Sacro Cuore, Rome, Italy."}]}},{"fullName":"Caira G","lastName":"Caira","firstName":"Giulia","initials":"G","authorAffiliationDetailsList":{"authorAffiliation":[{"affiliation":"Oncologia Medica, Comprehensive Cancer Center, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy; Oncologia Medica, Università Cattolica del Sacro Cuore, Rome, Italy."}]}},{"fullName":"Trovato G","lastName":"Trovato","firstName":"Giovanni","initials":"G","authorAffiliationDetailsList":{"authorAffiliation":[{"affiliation":"Oncologia Medica, Comprehensive Cancer Center, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy; Oncologia Medica, Università Cattolica del Sacro Cuore, Rome, Italy."}]}},{"fullName":"Spring A","lastName":"Spring","firstName":"Alexia","initials":"A","authorAffiliationDetailsList":{"authorAffiliation":[{"affiliation":"Oncologia Medica, Comprehensive Cancer Center, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy; Oncologia Medica, Università Cattolica del Sacro Cuore, Rome, Italy."}]}},{"fullName":"Beccia V","lastName":"Beccia","firstName":"Viria","initials":"V","authorAffiliationDetailsList":{"authorAffiliation":[{"affiliation":"Oncologia Medica, Comprehensive Cancer Center, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy; Oncologia Medica, Università Cattolica del Sacro Cuore, Rome, Italy."}]}},{"fullName":"Ceccarelli A","lastName":"Ceccarelli","firstName":"Anna","initials":"A","authorAffiliationDetailsList":{"authorAffiliation":[{"affiliation":"Oncologia Medica, Comprehensive Cancer Center, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy; Oncologia Medica, Università Cattolica del Sacro Cuore, Rome, Italy."}]}},{"fullName":"Perazzo S","lastName":"Perazzo","firstName":"Serena","initials":"S","authorAffiliationDetailsList":{"authorAffiliation":[{"affiliation":"Oncologia Medica, Comprehensive Cancer Center, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy; Oncologia Medica, Università Cattolica del Sacro Cuore, Rome, Italy."}]}},{"fullName":"Chiofalo L","lastName":"Chiofalo","firstName":"Laura","initials":"L","authorAffiliationDetailsList":{"authorAffiliation":[{"affiliation":"Oncologia Medica, Comprehensive Cancer Center, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy; Oncologia Medica, Università Cattolica del Sacro Cuore, Rome, Italy."}]}},{"fullName":"Barbaro B","lastName":"Barbaro","firstName":"Brunella","initials":"B","authorAffiliationDetailsList":{"authorAffiliation":[{"affiliation":"Radiologia Diagnostica e Interventistica Generale, Fondazione Policlinico Universitario Agostino Gemelli, IRCCS, Rome, Italy; Università Cattolica del Sacro Cuore, Rome, Italy."}]}},{"fullName":"Tatulli G","lastName":"Tatulli","firstName":"Giulia","initials":"G","authorAffiliationDetailsList":{"authorAffiliation":[{"affiliation":"Radiologia Diagnostica e Interventistica Generale, Fondazione Policlinico Universitario Agostino Gemelli, IRCCS, Rome, Italy; Università Cattolica del Sacro Cuore, Rome, Italy."}]}},{"fullName":"Alfieri S","lastName":"Alfieri","firstName":"Sergio","initials":"S","authorAffiliationDetailsList":{"authorAffiliation":[{"affiliation":"Chirurgia Digestiva, Fondazione Policlinico Universitario Agostino Gemelli, IRCCS, Rome, Italy; Università Cattolica del Sacro Cuore, Rome, Italy."}]}},{"fullName":"De Sio D","lastName":"De Sio","firstName":"Davide","initials":"D","authorId":{"type":"ORCID","value":"0000-0003-3739-4691"},"authorAffiliationDetailsList":{"authorAffiliation":[{"affiliation":"Chirurgia Digestiva, Fondazione Policlinico Universitario Agostino Gemelli, IRCCS, Rome, Italy."}]}},{"fullName":"Lorenzon L","lastName":"Lorenzon","firstName":"Laura","initials":"L","authorAffiliationDetailsList":{"authorAffiliation":[{"affiliation":"Chirurgia Generale, Fondazione Policlinico Universitario Agostino Gemelli, IRCCS, Rome, Italy."}]}},{"fullName":"Persiani R","lastName":"Persiani","firstName":"Roberto","initials":"R","authorAffiliationDetailsList":{"authorAffiliation":[{"affiliation":"Chirurgia Generale, Fondazione Policlinico Universitario Agostino Gemelli, IRCCS, Rome, Italy; Università Cattolica del Sacro Cuore, Rome, Italy."}]}},{"fullName":"Lococo F","lastName":"Lococo","firstName":"Filippo","initials":"F","authorAffiliationDetailsList":{"authorAffiliation":[{"affiliation":"Chirurgia Toracica, Fondazione Policlinico Universitario Agostino Gemelli, IRCCS, Rome, Italy; Università Cattolica del Sacro Cuore, Rome, Italy."}]}},{"fullName":"Nachira D","lastName":"Nachira","firstName":"Dania","initials":"D","authorAffiliationDetailsList":{"authorAffiliation":[{"affiliation":"Chirurgia Toracica, Fondazione Policlinico Universitario Agostino Gemelli, IRCCS, Rome, Italy."}]}},{"fullName":"Giuliante F","lastName":"Giuliante","firstName":"Felice","initials":"F","authorAffiliationDetailsList":{"authorAffiliation":[{"affiliation":"Chirurgia Generale ed Epato-Biliare, Fondazione Policlinico Universitario Agostino Gemelli, IRCCS, Rome, Italy; Università Cattolica del Sacro Cuore, Rome, Italy."}]}},{"fullName":"Ardito F","lastName":"Ardito","firstName":"Francesco","initials":"F","authorAffiliationDetailsList":{"authorAffiliation":[{"affiliation":"Chirurgia Generale ed Epato-Biliare, Fondazione Policlinico Universitario Agostino Gemelli, IRCCS, Rome, Italy; Università Cattolica del Sacro Cuore, Rome, Italy."}]}},{"fullName":"Cellini F","lastName":"Cellini","firstName":"Francesco","initials":"F","authorAffiliationDetailsList":{"authorAffiliation":[{"affiliation":"Radioterapia Oncologica, Fondazione Policlinico Universitario Agostino Gemelli, IRCCS, Rome, Italy; Università Cattolica del Sacro Cuore, Rome, Italy."}]}},{"fullName":"Panza G","lastName":"Panza","firstName":"Giulia","initials":"G","authorAffiliationDetailsList":{"authorAffiliation":[{"affiliation":"Radioterapia Oncologica, Fondazione Policlinico Universitario Agostino Gemelli, IRCCS, Rome, Italy."}]}},{"fullName":"Cozza V","lastName":"Cozza","firstName":"Valerio","initials":"V","authorAffiliationDetailsList":{"authorAffiliation":[{"affiliation":"Chirurgia d'Urgenza e del Trauma, Fondazione Policlinico Universitario Agostino Gemelli, IRCCS, Rome, Italy."}]}},{"fullName":"Giovinazzo F","lastName":"Giovinazzo","firstName":"Francesco","initials":"F","authorAffiliationDetailsList":{"authorAffiliation":[{"affiliation":"Chirurgia Generale e dei Trapianti di Organo, Fondazione Policlinico Universitario Agostino Gemelli, IRCCS, Rome, Italy."}]}},{"fullName":"Pafundi DP","lastName":"Pafundi","firstName":"Donato Paolo","initials":"DP","authorAffiliationDetailsList":{"authorAffiliation":[{"affiliation":"Chirurgia Generale 2, Fondazione Policlinico Universitario Agostino Gemelli, IRCCS, Rome, Italy."}]}},{"fullName":"Sofo L","lastName":"Sofo","firstName":"Luigi","initials":"L","authorAffiliationDetailsList":{"authorAffiliation":[{"affiliation":"Chirurgia Addominale, Fondazione Policlinico Universitario Agostino Gemelli, IRCCS, Rome, Italy; Università Cattolica del Sacro Cuore, Rome, Italy."}]}},{"fullName":"Santullo F","lastName":"Santullo","firstName":"Francesco","initials":"F","authorAffiliationDetailsList":{"authorAffiliation":[{"affiliation":"Chirurgia del Peritoneo e Retroperitone, Fondazione Policlinico Universitario Agostino Gemelli, IRCCS, Rome, Italy; Università Cattolica del Sacro Cuore, Rome, Italy."}]}},{"fullName":"Tondolo V","lastName":"Tondolo","firstName":"Vincenzo","initials":"V","authorAffiliationDetailsList":{"authorAffiliation":[{"affiliation":"Chirurgia Digestiva e del Colon Retto, Ospedale Isola Tiberina Gemelli Isola, Rome, Italy; Università Cattolica del Sacro Cuore, Rome, Italy."}]}},{"fullName":"Tortora G","lastName":"Tortora","firstName":"Giampaolo","initials":"G","authorAffiliationDetailsList":{"authorAffiliation":[{"affiliation":"Oncologia Medica, Comprehensive Cancer Center, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy; Oncologia Medica, Università Cattolica del Sacro Cuore, Rome, Italy."}]}},{"fullName":"Salvatore L","lastName":"Salvatore","firstName":"Lisa","initials":"L","authorAffiliationDetailsList":{"authorAffiliation":[{"affiliation":"Oncologia Medica, Comprehensive Cancer Center, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy; Oncologia Medica, Università Cattolica del Sacro Cuore, Rome, Italy. Electronic address: lisa.salvatore@policlinicogemelli.it."}]}}]},"authorIdList":{"authorId":[{"type":"ORCID","value":"0000-0003-3739-4691"}]},"dataLinksTagsList":{"dataLinkstag":["altmetrics"]},"journalInfo":{"issue":"2","volume":"24","journalIssueId":3946230,"dateOfPublication":"2025 Jun","monthOfPublication":6,"yearOfPublication":2025,"journal":{"medlineAbbreviation":"Clin Colorectal Cancer","title":"Clinical colorectal cancer","essn":"1938-0674","issn":"1533-0028","isoabbreviation":"Clin Colorectal Cancer","nlmid":"101120693"},"printPublicationDate":"2025-06-01"},"pubYear":"2025","pageInfo":"231-238","abstractText":"<h4>Background</h4>The management of colorectal cancer (CRC) is a complex process. Defining the disease burden, assessing the radiological response and identifying the right time for surgery or other locoregional treatments are crucial factors which can require the involvement of a multidisciplinary tumor board (MDTB) comprising several specialists. This study investigates the impact of MDTB on management of CRC in our institution.<h4>Methods</h4>We retrospectively assessed all cases discussed by our MDTB between September 2019 and April 2023. In particular, we collected data concerning radiology, surgery and radiotherapy indication before and after MDTB meetings. The primary endpoint was the overall rate of discrepancy between pre- and post-discussion evaluations.<h4>Results</h4>Our analysis involved 1150 cases. Median age was 64 years (16-90), 629 patients (54.7%) were male and 915 (79.5%) had metastatic disease at the time of the relevant MDTB discussion. After the meetings, 325 treatment decisions were modified, producing an overall discrepancy rate of 28.3%. In particular: (1) of 648 cases discussed for radiological assessment, 156 decisions (24.1%) were altered after a central imaging review; (2) of 327 cases considered for surgical approach, treatment strategy changed in 118 (36.1%); and (3) of the 160 cases discussed regarding radiotherapy, the treatment strategy changed in 51 of them (31.9%).<h4>Conclusions</h4>Our analysis shows significant discrepancies between the radiology and locoregional evaluations from both before and after the MDTB meetings. Our results highlight that the discussions of a MDTB can considerably change the management of CRC, maximizing the treatment strategy.","affiliation":"Oncologia Medica, Comprehensive Cancer Center, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy; Oncologia Medica, Università Cattolica del Sacro Cuore, Rome, Italy.","publicationStatus":"ppublish","language":"eng","pubModel":"Print-Electronic","pubTypeList":{"pubType":["Journal Article"]},"grantsList":{"grant":[{"agency":"Associazione Italiana per la Ricerca sul Cancro","grantId":"27367","orderIn":0}]},"meshHeadingList":{"meshHeading":[{"majorTopic_YN":"N","descriptorName":"Humans"},{"majorTopic_YN":"Y","descriptorName":"Colorectal Neoplasms","meshQualifierList":{"meshQualifier":[{"majorTopic_YN":"N","abbreviation":"PA","qualifierName":"pathology"},{"majorTopic_YN":"N","abbreviation":"TH","qualifierName":"therapy"}]}},{"majorTopic_YN":"N","descriptorName":"Retrospective Studies"},{"majorTopic_YN":"N","descriptorName":"Adolescent"},{"majorTopic_YN":"N","descriptorName":"Adult"},{"majorTopic_YN":"N","descriptorName":"Aged"},{"majorTopic_YN":"N","descriptorName":"Aged, 80 and over"},{"majorTopic_YN":"N","descriptorName":"Middle Aged"},{"majorTopic_YN":"Y","descriptorName":"Patient Care Team","meshQualifierList":{"meshQualifier":[{"majorTopic_YN":"N","abbreviation":"OG","qualifierName":"organization & administration"}]}},{"majorTopic_YN":"N","descriptorName":"Female"},{"majorTopic_YN":"N","descriptorName":"Male"},{"majorTopic_YN":"N","descriptorName":"Young Adult"},{"majorTopic_YN":"N","descriptorName":"Clinical Decision-Making","meshQualifierList":{"meshQualifier":[{"majorTopic_YN":"N","abbreviation":"MT","qualifierName":"methods"}]}}]},"keywordList":{"keyword":["Surgery","Radiotherapy","Colorectal Cancer","Multidisciplinary Tumor Board","Imaging Reviewing"]},"subsetList":{"subset":[{"code":"IM","name":"Index Medicus"}]},"fullTextUrlList":{"fullTextUrl":[{"availability":"Subscription required","availabilityCode":"S","documentStyle":"doi","site":"DOI","url":"https://doi.org/10.1016/j.clcc.2025.01.002"}]},"isOpenAccess":"N","inEPMC":"N","inPMC":"N","citedByCount":1,"hasReferences":"Y","hasTextMinedTerms":"Y","hasDbCrossReferences":"N","hasPDF":"N","hasBook":"N","hasSuppl":"N","hasLabsLinks":"Y","hasData":"N","authMan":"N","epmcAuthMan":"N","nihAuthMan":"N","hasTMAccessionNumbers":"N","dateOfCompletion":"2025-05-22","dateOfCreation":"2025-02-01","dateOfRevision":"2026-07-10","electronicPublicationDate":"2025-01-10","firstPublicationDate":"2025-01-10","firstIndexDate":"2025-02-03","hasEvaluations":"N"}]}}