
Enzyme
6.6.1.2 - Cobaltochelatase
Alternative Name(s)
- Hydrogenobyrinic acid a,c-diamide cobaltochelatase.
Catalytic Activity
ATP + Co(2+) + H2O + hydrogenobyrinate a,c-diamide = ADP + cob(II)yrinate a,c diamide + 5 H(+) + phosphate
Cofactors
There are no Cofactors for this Enzyme
Reaction Mechanism
There are no Reaction Mechanism for this Enzyme
Reaction Parameters
-
Kinetic Parameters
Organism KM Value [mM] Substrate Comment Pseudomonas denitrificans (nom. rej.) 0.22 ATP pH 8.0, 30°C -
Temperature
There are no reaction parameters information for this Enzyme.
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pH
There are no reaction parameters information for this Enzyme.
Associated Proteins
Citations
- Two Distinct Thermodynamic Gradients for Cellular Metalation of Vitamin B12.
- Crystal structure of the large subunit of cobaltochelatase from Mycobacterium tuberculosis.
- Sedimentary Cobalt Protoporphyrin as a Potential Precursor of Prosthetic Heme Group for Bacteria Inhabiting Fossil Organic Matter-Rich Shale Rock.
- Characterization and genomic analysis of an oceanic cyanophage infecting marine Synechococcus reveal a novel genus.
- Remarkably coherent population structure for a dominant Antarctic Chlorobium species.
- Revealing the Promoting Effect of Betaine on Vitamin B12 Biosynthetic Pathway of Pseudomonas denitrificans by Using a Proteomics Analysis.
- A Novel Freshwater Cyanophage Mae-Yong1326-1 Infecting Bloom-Forming Cyanobacterium Microcystis aeruginosa.
- Legionnaires' Disease in China Caused by Legionella pneumophila Corby.
- Enhanced cobalamin biosynthesis in Ensifer adhaerens by regulation of key genes with gradient promoters.
- Microcystin-LR-induced changes of hepatopancreatic transcriptome, intestinal microbiota, and histopathology of freshwater crayfish (Procambarus clarkii).
- VB12Path for Accurate Metagenomic Profiling of Microbially Driven Cobalamin Synthesis Pathways.