Cofactors

Mg(2+).

Reaction Mechanism

There are no Reaction Mechanism for this Enzyme

Reaction Parameters

There are no kinetic parameters information for this Enzyme

Associated Proteins

Citations

• A Lipoate-Protein Ligase Is Required for De Novo Lipoyl-Protein Biosynthesis in the Hyperthermophilic Archaeon Thermococcus kodakarensis.
• Lipoate protein ligase B primarily recognizes the C₈-phosphopantetheine arm of its donor substrate and weakly binds the acyl carrier protein.
• Lipoate protein ligase B primarily recognizes the C₈-phosphopantetheine arm of its donor substrate, and weakly binds the acyl carrier protein
• A Novel Lipoate-Protein Ligase, Mhp-LplJ, Is Required for Lipoic Acid Metabolism in Mycoplasma hyopneumoniae.
• Functional Identification and Structural Analysis of a New Lipoate Protein Ligase in Mycoplasma hyopneumoniae.
• Activation and competition of lipoylation of H protein and its hydrolysis in a reaction cascade catalyzed by the multifunctional enzyme lipoate-protein ligase A.
• Lipoate-Protein Ligase and Octanoyltransferase Are Essential for Protein Lipoylation in Mitochondria of Arabidopsis.
• Analytical studies on the conjugation site specificity of trastuzumab modified by Escherichia coli lipoate ligase A: multiple-enzyme digestion approach for peptide mapping.
• Identification of a novel lipoic acid biosynthesis pathway reveals the complex evolution of lipoate assembly in prokaryotes.
• The Streptomyces coelicolor lipoate-protein ligase is a circularly permuted version of the Escherichia coli enzyme composed of discrete interacting domains.
• The role of the Saccharomyces cerevisiae lipoate protein ligase homologue, Lip3, in lipoic acid synthesis.