22.214.171.124 - Threonine synthase
There are no alternative names for this Enzyme
H2O + O-phospho-L-homoserine = L-threonine + phosphate
|AA||Uniprot||Uniprot Resid||PDB||PDB Resid|
overall reactant used, proton transfer, overall product formed, intramolecular elimination, bimolecular nucleophilic addition, assisted tautomerisation (not keto-enol), native state of cofactor regenerated, intermediate formation, schiff base formed, intermediate terminated, native state of enzyme regenerated, cofactor used, proton relay, intermediate collapse
There are no kinetic parameters information for this Enzyme
- A mutation in THREONINE SYNTHASE 1 uncouples proliferation and transition domains of the root apical meristem: experimental evidence and in silico proposed mechanism.
- Modeling and simulation study to identify threonine synthase as possible drug target in Leishmania major.
- Reaction of threonine synthase with the substrate analogue 2-amino-5-phosphonopentanoate: implications into the proton transfer at the active site.
- Threonine synthase CoTHR4 is involved in infection-related morphogenesis during the pre-penetration stage in Colletotrichum orbiculare.
- Threonine synthase CoTHR4 is involved in infection-related morphogenesis during the pre-penetration stage in Colletotrichum orbiculare
- Molecular Mechanism of the Reaction Specificity in Threonine Synthase: Importance of the Substrate Conformations.
- Evolutionary analysis of a novel zinc ribbon in the N-terminal region of threonine synthase.
- Synthesis and biological evaluation of potential threonine synthase inhibitors: Rhizocticin A and Plumbemycin A.
- Assessment of the anti-inflammatory mechanism of quercetin 3,7-dirhamnoside using an integrated pharmacology strategy.
- A QM/MM study of the L-threonine formation reaction of threonine synthase: implications into the mechanism of the reaction specificity.
- New insights into glycogen synthase kinase-3: A common target for neurodegenerative diseases.