Enzyme

4.1.2.8 - Indole-3-glycerol-phosphate lyase

Alternative Name(s)
  • Indole synthase.
  • Indole-3-glycerol phosphate lyase.
  • phosphate-lyase.
  • Indole glycerol phosphate hydrolase.
  • Tryptophan synthase alpha.
  • Indole-3-glycerolphosphate D-glyceraldehyde-3-phosphate-lyase.
  • TSA.
  • (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate D-glyceraldehyde-3-
  • Indoleglycerolphosphate aldolase.

Catalytic Activity

(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate = D-glyceraldehyde 3-phosphate + indole

Cofactors

There are no Cofactors for this Enzyme

Reaction Mechanism

There are no Reaction Mechanism for this Enzyme

Reaction Parameters

  • Kinetic Parameters
    Organism KM Value [mM] Substrate Comment
    Oryza sativa 65.15 (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate pH 8.0, 22°C
  • Temperature

    There are no reaction parameters information for this Enzyme.

  • pH

    There are no reaction parameters information for this Enzyme.

Associated Proteins

Protein name Organism
Indole-3-glycerol phosphate lyase, chloroplastic Maize
Tryptophan synthase alpha chain Mouse-ear cress
Tryptophan synthase alpha chain, chloroplastic Mouse-ear cress
Indole-3-glycerol phosphate lyase variant 1 Guatemalan teosinte
Chloroplast indole-3-glycerol phosphate lyase Rye

Citations