Enzyme
3.6.1.61 - Diadenosine hexaphosphate hydrolase (ATP-forming)
Alternative Name(s)
There are no alternative names for this Enzyme
Catalytic Activity
H2O + P(1),P(4)-bis(5'-adenosyl) tetraphosphate = AMP + ATP + 2 H(+)
Cofactors
Divalent cation.
Reaction Mechanism
There are no Reaction Mechanism for this Enzyme
Reaction Parameters
-
Kinetic Parameters
Organism KM Value [mM] Substrate Comment Thermus thermophilus 2929 P1,P6-bis(5'-adenosyl)hexaphosphate pH 7.0, 25°C Escherichia coli 2.78 P1,P5-bis(5'-adenosyl)pentaphosphate pH 9.0, 37°C -
Temperature
There are no reaction parameters information for this Enzyme.
-
pH
There are no reaction parameters information for this Enzyme.
Associated Proteins
Citations
- The Phosin PptA Plays a Negative Role in the Regulation of Antibiotic Production in Streptomyces lividans.
- New Insight into Plant Signaling: Extracellular ATP and Uncommon Nucleotides.
- The Prodigal Compound: Return of Ribosyl 1,5-Bisphosphate as an Important Player in Metabolism.
- Cystathionine β-Synthase (CBS) Domain-containing Pyrophosphatase as a Target for Diadenosine Polyphosphates in Bacteria.
- InvA protein is a Nudix hydrolase required for infection by pathogenic Leptospira in cell lines and animals.
- YZGD from Paenibacillus thiaminolyticus, a pyridoxal phosphatase of the HAD (haloacid dehalogenase) superfamily and a versatile member of the Nudix (nucleoside diphosphate x) hydrolase superfamily.
- Diadenosine polyphosphate hydrolase from presynaptic plasma membranes of Torpedo electric organ.
- Role of the retinal vascular endothelial cell in ocular disease.
- ATP synthase and the actions of inhibitors utilized to study its roles in human health, disease, and other scientific areas.