Enzyme
3.2.2.9 - Adenosylhomocysteine nucleosidase
Alternative Name(s)
- S-adenosylhomocysteine nucleosidase.
- AdoHcy/MTA nucleosidase.
- S-adenosylhomocysteine/5'-methylthioadenosine nucleosidase.
- 5'-methyladenosine nucleosidase.
- S-adenosylhomocysteine hydrolase.
Catalytic Activity
H2O + S-adenosyl-L-homocysteine = adenine + S-(5-deoxy-D-ribos-5-yl)-L-homocysteine
Cofactors
There are no Cofactors for this Enzyme
Reaction Mechanism
There are no Reaction Mechanism for this Enzyme
Reaction Parameters
There are no kinetic parameters information for this Enzyme
Associated Proteins
Citations
- Crystal Structure of Aeromonas hydrophila Cytoplasmic 5'-Methylthioadenosine/S-Adenosylhomocysteine Nucleosidase.
- Structural and Functional Analyses of Periplasmic 5'-Methylthioadenosine/S-Adenosylhomocysteine Nucleosidase from Aeromonas hydrophila.
- Role of methylthioadenosine/S-adenosylhomocysteine nucleosidase in Vibrio cholerae cellular communication and biofilm development.
- Molecular dynamics study of the effect of active site protonation on Helicobacter pylori 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase.
- Cryo-electron microscopy of cytoskeletal ‘fibril’ involved inSpiroplasmaswimming
- Crystal structure and biochemical studies of Brucella melitensis 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase.
- Substrate preference of 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase in Burkholderia thailandensis.
- Methyl anthranilate deteriorates biofilm structure of Streptococcus suis and antagonizes the capsular polysaccharide defence effect.
- Screening for small molecule inhibitors of SAH nucleosidase using an SAH riboswitch.
- Decreased Transition-State Analogue Affinity in Isotopically Heavy MTAN with Increased Catalysis.
- Methylthioadenosine/S-adenosylhomocysteine nucleosidase (Pfs) of Staphylococcus aureus is essential for the virulence independent of LuxS/AI-2 system.