Enzyme

2.7.9.2 - Pyruvate, water dikinase

Alternative Name(s)
  • Pyruvate,water dikinase.
  • Phosphoenolpyruvate synthase.

Catalytic Activity

ATP + H2O + pyruvate = AMP + 2 H(+) + phosphate + phosphoenolpyruvate

Cofactors

Mn(2+).

Reaction Mechanism

There are no Reaction Mechanism for this Enzyme

Reaction Parameters

  • Kinetic Parameters
    Organism KM Value [mM] Substrate Comment
    Saccharolobus solfataricus 0.53 ATP 70°C, pH not specified in the publication
  • Temperature
    Organism Temperature Range Comment
    Pyrococcus furiosus 30 - 90 optimum at 90°C, 0.2% of the optimal activity at 30°C
  • pH

    There are no reaction parameters information for this Enzyme.

Associated Proteins

Protein name Organism
Phosphoenolpyruvate synthase Escherichia coli (strain K12)
Probable phosphoenolpyruvate synthase Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H)
Phosphoenol pyruvate synthase Assassin bug
Pyruvate, water dikinase Pelosinus sp. UFO1
PpsA7 Desulfobacterium autotrophicum (strain ATCC 43914 / DSM 3382 / HRM2)

Citations