
Enzyme
2.7.6.2 - Thiamine diphosphokinase
Alternative Name(s)
- Thiamine pyrophosphokinase.
- Thiamine kinase.
Catalytic Activity
ATP + thiamine = AMP + H(+) + thiamine diphosphate
Cofactors
There are no Cofactors for this Enzyme
Reaction Mechanism
There are no Reaction Mechanism for this Enzyme
Reaction Parameters
There are no kinetic parameters information for this Enzyme
Associated Proteins
Citations
- Wernicke Encephalopathy: An Updated Narrative Review.
- The advanced glycation end product-lowering agent ALT-711 is a low-affinity inhibitor of thiamine diphosphokinase.
- Repurposing the natural compounds as potential therapeutic agents for COVID-19 based on the molecular docking study of the main protease and the receptor-binding domain of spike protein.
- In silico genomic analysis of the potential probiotic Lactiplantibacillus pentosus CF2-10N reveals promising beneficial effects with health promoting properties.
- In Silico Identification of Potential Therapeutic Agents for COVID-19 Based on Molecular Docking Study of Main Protease and Receptor Binding Domain of Spike Protein.
- Hiding in Plain Sight: Modern Thiamine Deficiency.
- Mitochondrial transport and metabolism of the vitamin B-derived cofactors thiamine pyrophosphate, coenzyme A, FAD and NAD+ , and related diseases: A review.
- Wernicke's encephalopathy - from basic science to clinical practice. Part 1: Understanding the role of thiamine.
- Update on Thiamine Triphosphorylated Derivatives and Metabolizing Enzymatic Complexes.
- Novel kinase platform for the validation of the anti-tubercular activities of Pelargonium sidoides (Geraniaceae).
- Activation of Mitochondrial 2-Oxoglutarate Dehydrogenase by Cocarboxylase in Human Lung Adenocarcinoma Cells A549 Is p53/p21-Dependent and Impairs Cellular Redox State, Mimicking the Cisplatin Action.