
Enzyme
2.7.1.145 - Deoxynucleoside kinase
Alternative Name(s)
- Ms-dNK.
- Multifunctional deoxynucleoside kinase.
- Multispecific deoxynucleoside kinase.
- Multisubstrate deoxyribonucleoside kinase.
Catalytic Activity
2'-deoxyribonucleoside + ATP = a 2'-deoxyribonucleoside 5'-phosphate + ADP + H(+)
Cofactors
There are no Cofactors for this Enzyme
Reaction Mechanism
There are no Reaction Mechanism for this Enzyme
Reaction Parameters
There are no kinetic parameters information for this Enzyme
Associated Proteins
Citations
- Biological phosphorylation of an Unnatural Base Pair (UBP) using a Drosophila melanogaster deoxynucleoside kinase (DmdNK) mutant.
- A Single Deoxynucleoside Kinase Variant from Drosophila melanogaster Synthesizes Monophosphates of Nucleosides That Are Components of an Expanded Genetic System.
- Efficient production of deoxynucleoside-5'-monophosphates using deoxynucleoside kinase coupled with a GTP-regeneration system.
- Vpx requires active cellular dNTP biosynthesis to effectively counteract the anti-lentivirus activity of SAMHD1 in macrophages.
- NME6: ribonucleotide salvage sustains mitochondrial transcription.
- Recursive genome engineering decodes the evolutionary origin of an essential thymidylate kinase activity in Pseudomonas putida KT2440.
- Screening the Thermotoga maritima genome for new wide-spectrum nucleoside and nucleotide kinases.
- Cytotoxic effect of Drosophila deoxynucleoside kinase gene on replicating plasmid in HeLa cells.
- Use of Drosophila deoxynucleoside kinase to study mechanism of toxicity and mutagenicity of deoxycytidine analogs in Escherichia coli.
- Thymidine nucleotide metabolism controls human telomere length.
- Early-Phase Drive to the Precursor Pool: Chloroviruses Dive into the Deep End of Nucleotide Metabolism.