Enzyme
2.3.1.57 - Diamine N-acetyltransferase
Alternative Name(s)
- Putrescine (diamine)-acetylating enzyme.
- Putrescine acetylase.
- Putrescine acetyltransferase.
- Acetyl-coenzyme A-1,4-diaminobutane N-acetyltransferase.
- Putrescine N-acetyltransferase.
- Diamine acetyltransferase.
- Spermidine acetyltransferase.
- Spermidine N(1)-acetyltransferase.
Catalytic Activity
yl-CoA + an alkane-alpha,omega-diamine = an N-acetylalkane-alpha,omega-diamine + CoA + H(+)
Cofactors
There are no Cofactors for this Enzyme
Reaction Mechanism
There are no Reaction Mechanism for this Enzyme
Reaction Parameters
There are no kinetic parameters information for this Enzyme
Associated Proteins
Citations
- Polyamine-Derived Aminoaldehydes and Acrolein: Cytotoxicity, Reactivity and Analysis of the Induced Protein Modifications.
- MYC-driven U2SURP regulates alternative splicing of SAT1 to promote triple-negative breast cancer progression.
- DLAT is a promising prognostic marker and therapeutic target for hepatocellular carcinoma: a comprehensive study based on public databases.
- Sertoli cell-enriched proteins in mouse and human testicular interstitial fluid.
- Synthesis and In Situ Behavior of 1,4- and 2,5-(13C) Isotopomers of p-Phenylenediamine in Reconstructed Human Epidermis Using High Resolution Magic Angle Spinning NMR.
- Indomethacin Induces Spermidine/Spermine-N1-Acetyltransferase-1 via the Nucleolin-CDK1 Axis and Synergizes with the Polyamine Oxidase Inhibitor Methoctramine in Lung Cancer Cells.
- Structure-Guided Design of N-Methylpropargylamino-Quinazoline Derivatives as Multipotent Agents for the Treatment of Alzheimer's Disease.
- Genomic and structural basis for evolution of tropane alkaloid biosynthesis.
- Uptake and Biotransformation of the Tire Rubber-derived Contaminants 6-PPD and 6-PPD Quinone in the Zebrafish Embryo (Danio rerio).
- Sterubin protects against chemically-induced Alzheimer's disease by reducing biomarkers of inflammation- IL-6/ IL-β/ TNF-α and oxidative stress- SOD/MDA in rats.
- Loss-of-function variants in SAT1 cause X-linked childhood-onset systemic lupus erythematosus.