
Enzyme
1.6.1.1 - NAD(P)(+) transhydrogenase (Si-specific)
Alternative Name(s)
- Nicotinamide nucleotide transhydrogenase.
- Pyridine nucleotide transhydrogenase.
- NAD(P)(+) transhydrogenase (B-specific).
Catalytic Activity
NAD(+) + NADPH = NADH + NADP(+)
Cofactors
FAD.
Reaction Mechanism
There are no Reaction Mechanism for this Enzyme
Reaction Parameters
-
Kinetic Parameters
Organism KM Value [mM] Substrate Comment Escherichia coli 1940 thio-NAD+ at pH 7.5 and 35°C -
Temperature
Organism Temperature Range Comment Escherichia coli 20 - 45 more than 70% activity between 20 and 45°C -
pH
Organism pH Range Comment Escherichia coli 7 - 9 more than 50% activity between pH 7.0 and 9.0 Azotobacter vinelandii 8.4 - 8.7 half maximal activity in this pH range in the absence of Ca2+ or Mg2+, no activity above
Associated Proteins
Citations
- Constitutive glucose dehydrogenase elevates intracellular NADPH levels and luciferase luminescence in Bacillus subtilis.
- Engineering Bacillus subtilis for production of 3-hydroxypropanoic acid.
- Protein cost minimization promotes the emergence of coenzyme redundancy.
- A mutant fitness assay identifies bacterial interactions in a model ocean hot spot.
- Proteomic dataset comparing strains of Leptospira borgpetersenii serovar Hardjo cultured at different temperatures.
- A comparative genome analysis of the Bacillota (Firmicutes) class Dehalobacteriia.
- Metabolic landscape in cardiac aging: insights into molecular biology and therapeutic implications.
- Long-Chain and Medium-Chain Fatty Acids in Energy Metabolism of Murine Kidney Mitochondria.
- Into the darkness: the ecologies of novel 'microbial dark matter' phyla in an Antarctic lake.
- Finding Species-Specific Extracellular Surface-Facing Proteomes in Toxic Dinoflagellates.
- Unveiling chlorpyrifos mineralizing and tomato plant-growth activities of Enterobacter sp. strain HSTU-ASh6 using biochemical tests, field experiments, genomics, and in silico analyses.