220.127.116.11 - Malate dehydrogenase (decarboxylating)
- Malic enzyme.
- Pyruvic-malic carboxylase.
- NAD-malic enzyme.
(S)-malate + NAD(+) = CO2 + NADH + pyruvate
There are no Cofactors for this Enzyme
There are no Reaction Mechanism for this Enzyme
Organism KM Value [mM] Substrate Comment Arabidopsis thaliana 10.3 (S)-malate pH 6.4, temperature not specified in the publication, NAD-ME1 Rhodopseudomonas palustris 2900 NADP+ pH 7.2, 30°C, with (S)-malate
Organism Temperature Range Comment Brevundimonas diminuta 30 - 60 30°C: about 35% of maximal activity, 60°C: about 50% of maximal activity
Organism pH Range Comment Solanum tuberosum 5.8 - 7.6 pH 5.8: about 60% of maximal activity, pH 7.6: about 40% of maximal activity Clupea harengus 6 - 8 decarboxylation reaction, activity range Brevundimonas diminuta 6 - 8.5 about 40% of maximal activity at pH 6.0 and at pH 8.5 Glossina morsitans 7 - 8.7 pH 7.0: about 30% of maximal activity, pH 8.7: about 45% of maximal activity
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