ID   U09422; SV 1; circular; genomic DNA; STD; PRO; 18032 BP.
XX
AC   U09422;
XX
DT   08-SEP-1994 (Rel. 40, Created)
DT   14-NOV-2006 (Rel. 89, Last updated, Version 12)
XX
DE   Enterococcus faecalis DS16 transposon Tn916, (tet(M)), (Xis-Tn), (Int-Tn)
DE   genes, ORFs 1-24, complete cds, complete sequence.
XX
KW   .
XX
OS   Enterococcus faecalis
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
OC   Enterococcus.
XX
RN   [1]
RP   1-18032
RX   DOI; 10.1006/plas.1994.1077.
RX   PUBMED; 7899523.
RA   Flannagan S.E., Zitzow L.A., Su Y.A., Clewell D.B.;
RT   "Nucleotide sequence of the 18-kb conjugative transposon Tn916 from
RT   Enterococcus faecalis";
RL   Plasmid 32(3):350-354(1994).
XX
RN   [2]
RP   14028-18032
RX   DOI; 10.1006/plas.1993.1055.
RX   PUBMED; 8302931.
RA   Su Y.A., Clewell D.B.;
RT   "Characterization of the left 4 kb of conjugative transposon Tn916:
RT   determinants involved in excision";
RL   Plasmid 30(3):234-250(1993).
XX
RN   [3]
RP   11603-14393
RX   PUBMED; 1323953.
RA   Su Y.A., He P., Clewell D.B.;
RT   "Characterization of the tet(M) determinant of Tn916: evidence for
RT   regulation by transcription attenuation";
RL   Antimicrob. Agents Chemother. 36(4):769-778(1992).
XX
RN   [4]
RP   1-262,17801-18032
RX   PUBMED; 2838457.
RA   Clewell D.B., Flannagan S.E., Ike Y., Jones J.M., Gawron-Burke C.;
RT   "Sequence analysis of termini of conjugative transposon Tn916";
RL   J. Bacteriol. 170(7):3046-3052(1988).
XX
RN   [5]
RP   1-18032
RA   Clewell D.B.;
RT   ;
RL   Submitted (04-MAY-1994) to the INSDC.
RL   Don B. Clewell, Biologic and Materials Sciences, The University of
RL   Michigan, 2310G School of Dentistry, Ann Arbor, MI 48109-1078, USA
XX
DR   MD5; d26356a24cda72854eedefd9c105c2e2.
DR   EuropePMC; PMC101640; 11036060.
DR   EuropePMC; PMC1140533; 15917571.
DR   EuropePMC; PMC1315971; 16304174.
DR   EuropePMC; PMC1346803; 16377687.
DR   EuropePMC; PMC151939; 12399502.
DR   EuropePMC; PMC154524; 12732544.
DR   EuropePMC; PMC1610078; 17005818.
DR   EuropePMC; PMC1636245; 17015654.
DR   EuropePMC; PMC165177; 12839793.
DR   EuropePMC; PMC1855496; 17261630.
DR   EuropePMC; PMC1855514; 17210772.
DR   EuropePMC; PMC2151433; 17709462.
DR   EuropePMC; PMC2292545; 18285489.
DR   EuropePMC; PMC2630629; 19001115.
DR   EuropePMC; PMC2698359; 19395574.
DR   EuropePMC; PMC2753074; 19666731.
DR   EuropePMC; PMC3158075; 21876735.
DR   EuropePMC; PMC3194845; 21784909.
DR   EuropePMC; PMC3457367; 22802249.
DR   EuropePMC; PMC3542815; 22723288.
DR   EuropePMC; PMC3754347; 23817370.
DR   EuropePMC; PMC415626; 15155196.
DR   EuropePMC; PMC4604367; 26282424.
DR   EuropePMC; PMC5116939; 27698087.
DR   EuropePMC; PMC5181394; 27494928.
DR   EuropePMC; PMC5225093; 28123380.
DR   EuropePMC; PMC5473281; 28619812.
DR   EuropePMC; PMC5733627; 28333320.
DR   EuropePMC; PMC5872130; 29509667.
DR   EuropePMC; PMC6292373; 30598735.
DR   EuropePMC; PMC94161; 10559152.
DR   EuropePMC; PMC97936; 11159952.
XX
FH   Key             Location/Qualifiers
FH
FT   source          1..18032
FT                   /organism="Enterococcus faecalis"
FT                   /strain="DS16"
FT                   /mol_type="genomic DNA"
FT                   /db_xref="taxon:1351"
FT   mobile_element  1..18032
FT                   /mobile_element_type="transposon:Tn916"
FT   CDS             194..313
FT                   /codon_start=1
FT                   /transl_table=11
FT                   /note="ORF24"
FT                   /db_xref="UniProtKB/TrEMBL:Q47724"
FT                   /protein_id="AAB60009.1"
FT                   /translation="MRCLFFYPILKGSELMKTKNQESKGRSPLFKTIKHSFSQ"
FT   CDS             336..650
FT                   /codon_start=1
FT                   /transl_table=11
FT                   /note="ORF23"
FT                   /db_xref="InterPro:IPR010365"
FT                   /db_xref="InterPro:IPR038620"
FT                   /db_xref="UniProtKB/TrEMBL:Q47725"
FT                   /protein_id="AAB60010.1"
FT                   /translation="MELKFVIPNMEKTFGNLEFAGEDKVVQRRINGRLTVLSRSYNLYS
FT                   DVQRADDIVVVLPAEAGEKHFGFEERVKLVNPRITAEGYKIGTRGFTNYLLHADDMIKE
FT                   "
FT   CDS             666..1052
FT                   /codon_start=1
FT                   /transl_table=11
FT                   /note="ORF22"
FT                   /db_xref="InterPro:IPR010365"
FT                   /db_xref="InterPro:IPR038620"
FT                   /db_xref="UniProtKB/TrEMBL:Q47726"
FT                   /protein_id="AAB60011.1"
FT                   /translation="MMRLANGIVLDKDTTFGELKFSALRREVRIQNEDGSVSDEIKERT
FT                   YDLKSKGQGRMIQVSIPASVPLKEFDYNARVELINPIADTVATATYQGADVDWYIKADD
FT                   IVLTKDSSSFKAQPQAKKEPTQDK"
FT   CDS             1081..2466
FT                   /codon_start=1
FT                   /transl_table=11
FT                   /note="ORF21"
FT                   /db_xref="GOA:Q47727"
FT                   /db_xref="InterPro:IPR002543"
FT                   /db_xref="InterPro:IPR027417"
FT                   /db_xref="UniProtKB/TrEMBL:Q47727"
FT                   /protein_id="AAB60012.1"
FT                   /translation="MKQRGKRIRPSGKDLVFHFTIASLLPVFLLVVGLFHVKTIQQINW
FT                   QDFNLSQADKIDIPYLIISFSVAILICLLVAFVFKRVRYDTVKQLYHRQKLAKMILENK
FT                   WYESEQVKTEGFFKDSAGRTKEKITYFPKMYYRLKNGLIQIRVEITLGKYQDQLLHLEK
FT                   KLESGLYCELTDKELKDSYVEYTLLYDTIASRISIDEVEAKDGKLRLMKNVWWEYDKLP
FT                   HMLIAGGTGGGKTYFILTLIEALLHTDSKLYILDPKNADLADLGSVMANVYYRKEDLLS
FT                   CIETFYEEMMKRSEEMKQMKNYKTGKNYAYLGLPAHFLIFDEYVAFMEMLGTKENTAVM
FT                   NKLKQIVMLGRQAGFFLILACQRPDAKYLGDGIRDQFNFRVALGRMSEMGYGMMFGSDV
FT                   QKDFFLKRIKGRGYVDVGTSVISEFYTPLVPKGYDFLEEIKKLSNSRQSTQATCEAEVA
FT                   GVD"
FT   CDS             2861..3850
FT                   /codon_start=1
FT                   /transl_table=11
FT                   /note="ORF20"
FT                   /db_xref="GOA:Q47728"
FT                   /db_xref="InterPro:IPR003491"
FT                   /db_xref="InterPro:IPR040819"
FT                   /db_xref="UniProtKB/TrEMBL:Q47728"
FT                   /protein_id="AAB60013.1"
FT                   /translation="MLFDYVRIRFPTTDVQQVVENILQLKLSYFLHEDYGFYSYSEHYA
FT                   LGDIFVLCSHELDKGVLVELKGRGCRQFESYLLAQQRSWYEFFMDVLVAGGVMKRLDLA
FT                   INDKTGILNIPVLTEKCQQEECISVFRSFKSYRSGELVRKEEKECMGNTLYIGSLQSEV
FT                   YFCIYEKDYEQYKKNDIPIEDAEVKNRFEIRLKNERAYYAVRDLLVYDNPEHTAFKIIN
FT                   RYIRFVDKDDSKPRSDWKLNEEWAWFIGNNRERLKLTTKPEPYSFQRTLNWLSHQVAPT
FT                   LKVAIKLDEINQTQVVKDILDHAKLTDRHKQILKQQSVKEQDVITTKK"
FT   CDS             3893..4114
FT                   /codon_start=1
FT                   /transl_table=11
FT                   /note="ORF19"
FT                   /db_xref="GOA:Q47729"
FT                   /db_xref="UniProtKB/TrEMBL:Q47729"
FT                   /protein_id="AAB60014.1"
FT                   /translation="MNFGQNLYNWFLSNAQSLVLLAIVVIGLYLGFKREFSKLIGFLII
FT                   AIIAVGLVFNAAGVKDILLELFNRIIGA"
FT   CDS             4231..4728
FT                   /codon_start=1
FT                   /transl_table=11
FT                   /note="ORF18"
FT                   /db_xref="GOA:Q47730"
FT                   /db_xref="InterPro:IPR009899"
FT                   /db_xref="InterPro:IPR041893"
FT                   /db_xref="InterPro:IPR041895"
FT                   /db_xref="InterPro:IPR041896"
FT                   /db_xref="PDB:2W82"
FT                   /db_xref="UniProtKB/TrEMBL:Q47730"
FT                   /protein_id="AAB60015.1"
FT                   /translation="MDDMQVYIANLGKYNEGELVGAWFTFPIDFEEVKEKIGLNDEYEE
FT                   YAIHDYELPFTVDEYTSIGELNRLWEMVSELPEELQSELSALLTHFSSIEELSEHQEDI
FT                   IIHSDCDDMYDVARYYIEETGALGEVPASLQNYIDYQAYGRDLDLSGTFISTNHGIFEI
FT                   VY"
FT   CDS             4703..5209
FT                   /codon_start=1
FT                   /transl_table=11
FT                   /note="ORF17"
FT                   /db_xref="GOA:Q47731"
FT                   /db_xref="InterPro:IPR025608"
FT                   /db_xref="UniProtKB/TrEMBL:Q47731"
FT                   /protein_id="AAB60016.1"
FT                   /translation="MGFLKSSIKSVGTLLLADFLFYGVAQSATPIFYERIDYMKKIRSY
FT                   TSIWSVEKVLYSINDFRLPFPITFTQMTWFVVSLFAVMILGNLPPLSMIEGAFLKYFGI
FT                   PVAFTWFMSTKTFDGKKPYGFLKSVIAYALRPKLTYAGKKVTLGRNQPQEAITAVRSEF
FT                   YGISN"
FT   CDS             5193..7640
FT                   /codon_start=1
FT                   /transl_table=11
FT                   /note="ORF16"
FT                   /db_xref="GOA:Q47732"
FT                   /db_xref="InterPro:IPR016628"
FT                   /db_xref="InterPro:IPR027417"
FT                   /db_xref="UniProtKB/TrEMBL:Q47732"
FT                   /protein_id="AAB60017.1"
FT                   /translation="MAYPIKYIENNLVWNKDGECYAYYELVPYNYSFLSPEQKIQVHDS
FT                   FRQLIAQNRDGKIHALQISTESSIRSAQERSKNEVTGKLKAVAYDKIDQQTDALISMIG
FT                   ENQVNYRFFIGFKLLLNDQEFSMKSLTVEAKNALSDFVYDVNHKLMGDFVSMSNDEILR
FT                   FQKMEKLLENKISRRFKIRRLDKDDFGYLIEHLYGQTGTAYEEYEYHLSKKKLDNETLI
FT                   KYYDLIKPTRCLVEEKQRYLKIQQEDETVYVAYFTINSIVGELDFPSSEIFYYQQQQFT
FT                   FPIDTSMNVEIVANRKALSTVRNKKKELKDLDNHAWQSDNETSSNVAEALESVNELETN
FT                   LDQSKESMYKLSYVVRVSANDLDELKRRCNEVKDFYDDLSVKLVRPFGDMLGLHEEFLP
FT                   ASKRYMNDYIQYVTSDFLAGLGFGATQMLGENEGIYVGYSLDTGRNVYLKPALASQGVK
FT                   GSVTNALASAFVGSLGGGKSFANNLIVYYAVLYGAQAVIVDPKAERGRWKETLPEISHE
FT                   INIVTLTSDEKNKGLLDPYVIMKNPKDSESLAIDILTFLTGISSRDGERFPILRKAIRA
FT                   VTNSEVRGLMKVIEELRVENTPLSTSIADHIESFTDYDFAHLLFSNGYVEQSISLEKQL
FT                   NIIQVADLVLPDKETSFEEYTTMELLSVAMLIVISTFALDFIHTDRSIFKIVDLDEAWS
FT                   FLQVAQGKTLSMKLVRAGRAMNAGVYFVTQNTDDLLDEKLKNNLGLKFAFRSTDLNEIK
FT                   KTLAFFGVDPEDENNQKRLRDLENGQCLISDLYGRVGVIQFHPVFEELLHAFDTRPPVR
FT                   KEV"
FT   CDS             7643..9907
FT                   /codon_start=1
FT                   /transl_table=11
FT                   /note="ORF15"
FT                   /db_xref="GOA:Q47733"
FT                   /db_xref="UniProtKB/TrEMBL:Q47733"
FT                   /protein_id="AAB60018.1"
FT                   /translation="MKPSIVNRIKSNWTLKRLGKVAMTVAFTLVIAIFLLAMLGTVVQA
FT                   AGLVDDTVNVANEYSRYPLENYQLDFYVDNSWGWLPWNWSDGIGKQVMYGLYAITNFIW
FT                   TISLYVSNATGYLVQEAYSLDFISATADSIGKNMQTLAGVSANGFSTEGFYVGFLLLLI
FT                   LVLGVYVAYTGLIKRETTKAIHAIMNFVLVFILSASFIAYAPDYIKKINDFSSDISNAS
FT                   LSLGTKIVMPHSDSQGKDSVDLIRDSLFSIQVQQPWLLLQYNSSDIESIGIDRVESLLS
FT                   TSPDSNNGEDREKIVAEEIEDRSNTNLTITKTINRLGTVFFLFVFNIGISIFVFLLTGI
FT                   MIFSQVLFIIYAMFLPVSFILSMIPSFDGMSKRAITKLFNTILTRAGITLIITTAFSIS
FT                   TMLYTLSAGYPFFLIAFLQIVTFAGIYFKLGDLMSMFSLQSNDSQSVGSRVMRKPRMLM
FT                   HAHMHRLQRKLGRSMTTLGAGSAIVTGKKGQSGSGSSARTQADHSRPDGKEKSTLGKRI
FT                   GQTIGTVADTKDRMVDTASGLKEQVKDLPTNARYAVYQGKSKVKENVRDLTSSISQTKA
FT                   DRASGRKEQQEQRRKTIAKRRSEMEQVKQKKQPASSVHERPTTRQEQYHDEQTSKQSNI
FT                   QTSYKESQQAKQERPAVKSDFSSPKVERKAIPFKKKPFKSQQLQPLQQIELHNVQSQKN
FT                   VRLLFKEYHYKIQEVDHQSKPPPLRKSVRNHEVENFSDWWFWIILDGLLTASVCCHFIF
FT                   R"
FT   CDS             9816..10817
FT                   /codon_start=1
FT                   /transl_table=11
FT                   /note="ORF14"
FT                   /db_xref="GOA:Q47734"
FT                   /db_xref="InterPro:IPR000064"
FT                   /db_xref="InterPro:IPR023346"
FT                   /db_xref="InterPro:IPR038765"
FT                   /db_xref="UniProtKB/TrEMBL:Q47734"
FT                   /protein_id="AAB60019.1"
FT                   /translation="MKLKTLVIGGSGLFLMVFSLLLFVAILFSDEQDSGISNIHYGGVN
FT                   VSAEVLAHKPMVEKYAKEYGVEEYVNILLAIIQVESGGTAEDVMQSSESLGLPPNSLST
FT                   EESIKQGVKYFSELLASSERLSVDLESVIQSYNYGGGFLGYVANRGNKYTFELAQSFSK
FT                   EYSGGEKVSYPNPIAIPINGGWRYNYGNMFYVQLVTQYLVTTEFDDDTVQAIMDEALKY
FT                   EGWRYVYGGASPTTSFDCSGLTQWTYGKAGINLPRTAQQQYDVTQHIPLSEAQAGDLVF
FT                   FHSTYNAGSYITHVGIYLGNNRMFHAGDPIGYADLTSPYWQQHLVGAGRIKQ"
FT   CDS             10814..11746
FT                   /codon_start=1
FT                   /transl_table=11
FT                   /note="ORF13"
FT                   /db_xref="InterPro:IPR024735"
FT                   /db_xref="InterPro:IPR035628"
FT                   /db_xref="UniProtKB/TrEMBL:Q47735"
FT                   /protein_id="AAB60020.1"
FT                   /translation="MRKEDLMMKFRKNQNKEKQIPKEKKPRVYKVNPHKKVVIALWVLL
FT                   GLSFSFAIFKHFTAIDTHTIHETTIIEKEYVDTHHVENFVENFAKVYYSWEQSDKSIDN
FT                   RMESLKGYLTDELQALNVDTVRKDIPVSSSVRGFQIWTVEPTGDNEFNVTYSVDQLITE
FT                   GENTKTVHSAYIVSVYVDGSGNMVLVKNPTITNIPKKSSYKPKAIESEGTVDSITTNEI
FT                   NEFLTTFFKLYPTATASELSYYVNDGILKPIGKEYIFQELVNPIHNRKDNQVTVSLTVE
FT                   YIDQQTKATQVSQFDLVLEKNGSNWKIIE"
FT   old_sequence    11737
FT                   /replace=""
FT                   /note="in ORF13"
FT                   /citation=[3]
FT   CDS             12021..12107
FT                   /codon_start=1
FT                   /transl_table=11
FT                   /product="tet(M) leader peptide"
FT                   /note="ORF12"
FT                   /db_xref="InterPro:IPR012992"
FT                   /db_xref="UniProtKB/TrEMBL:Q47736"
FT                   /protein_id="AAB60021.1"
FT                   /translation="MLCMPMVMHKNPSDKSIYHWDFYALLGF"
FT   CDS             12123..14042
FT                   /codon_start=1
FT                   /transl_table=11
FT                   /gene="tet(M)"
FT                   /note="ORF11"
FT                   /db_xref="GOA:Q57224"
FT                   /db_xref="InterPro:IPR000640"
FT                   /db_xref="InterPro:IPR000795"
FT                   /db_xref="InterPro:IPR005225"
FT                   /db_xref="InterPro:IPR005517"
FT                   /db_xref="InterPro:IPR009000"
FT                   /db_xref="InterPro:IPR014721"
FT                   /db_xref="InterPro:IPR020568"
FT                   /db_xref="InterPro:IPR027417"
FT                   /db_xref="InterPro:IPR031157"
FT                   /db_xref="InterPro:IPR035647"
FT                   /db_xref="InterPro:IPR035650"
FT                   /db_xref="InterPro:IPR041095"
FT                   /db_xref="UniProtKB/TrEMBL:Q57224"
FT                   /protein_id="AAB60022.1"
FT                   /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDN
FT                   TLLERQRGITIQTGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDG
FT                   VQAQTRILFHALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVELYPN
FT                   VCVTNFTESEQWDTVIEGNDDLLEKYMSGKSLEALELEQEESIRFQNCSLFPLYHGSAK
FT                   SNIGIDNLIEVITNKFYSSTHRGPSELCGNVFKIEYTKKRQRLAYIRLYSGVLHLRDSV
FT                   RVSEKEKIKVTEMYTSINGELCKIDRAYSGEIVILQNEFLKLNSVLGDTKLLPQRKKIE
FT                   NPHPLLQTTVEPSKPEQREMLLDALLEISDSDPLLRYYVDSTTHEIILSFLGKVQMEVI
FT                   SALLQEKYHVEIELKEPTVIYMERPLKNAEYTIHIEVPPNPFWASIGLSVSPLPLGSGM
FT                   QYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYSPVSTPADFR
FT                   MLAPIVLEQVLKKAGTELLEPYLSFKIYAPQEYLSRAYNDAPKYCANIVDTQLKNNEVI
FT                   LSGEIPARCIQEYRSDLTFFTNGRSVCLTELKGYHVTTGEPVCQPRRPNSRIDKVRYMF
FT                   NKIT"
FT   CDS             14140..14328
FT                   /codon_start=1
FT                   /transl_table=11
FT                   /note="ORF6"
FT                   /db_xref="InterPro:IPR025957"
FT                   /db_xref="UniProtKB/TrEMBL:Q56396"
FT                   /protein_id="AAB60023.1"
FT                   /translation="MINYKWILCPVCGNKTRLKIREDTELKKFPLYCPKCRQENLIEIK
FT                   QFKVTVITEPDAKTQSR"
FT   CDS             complement(14388..14741)
FT                   /codon_start=1
FT                   /transl_table=11
FT                   /note="ORF9"
FT                   /db_xref="GOA:Q56397"
FT                   /db_xref="InterPro:IPR001387"
FT                   /db_xref="InterPro:IPR010982"
FT                   /db_xref="InterPro:IPR041511"
FT                   /db_xref="UniProtKB/TrEMBL:Q56397"
FT                   /protein_id="AAB60024.1"
FT                   /translation="MRKKEDKYDFRAFGLAIKEARLQRGLTREQVGALIEIDPRYLTNI
FT                   ENKGQHPSIQVLYDLVSLLHVSVDEFFLPANNLVKSTRRLQIEKYMDSFTDKELSLMES
FT                   LASGINEARNIED"
FT   CDS             14946..15017
FT                   /codon_start=1
FT                   /transl_table=11
FT                   /note="ORF10"
FT                   /db_xref="UniProtKB/TrEMBL:Q57162"
FT                   /protein_id="AAB60025.1"
FT                   /translation="MKYIIYNKFPYIGFLSKKVVYLQ"
FT   CDS             15195..15668
FT                   /codon_start=1
FT                   /transl_table=11
FT                   /note="ORF7"
FT                   /db_xref="GOA:Q56398"
FT                   /db_xref="InterPro:IPR013249"
FT                   /db_xref="InterPro:IPR013324"
FT                   /db_xref="InterPro:IPR014284"
FT                   /db_xref="InterPro:IPR036388"
FT                   /db_xref="UniProtKB/TrEMBL:Q56398"
FT                   /protein_id="AAB60026.1"
FT                   /translation="MNEQGSLPFLDRKGVRNMKPSSFQTTIENQFDYICKRAMEDERKN
FT                   YMLYLSRIAKREVSFSDVGDYLVSQFATTDNYSTDFQIFTLNGLSVGVENDLLSEALRE
FT                   LPDKKREILLLFYFMDMSDSEIADLLKLNRSTVYRHRTSGLALIKKFMEEFEE"
FT   CDS             15665..15895
FT                   /codon_start=1
FT                   /transl_table=11
FT                   /note="ORF8"
FT                   /db_xref="InterPro:IPR024760"
FT                   /db_xref="UniProtKB/TrEMBL:Q57216"
FT                   /protein_id="AAB60027.1"
FT                   /translation="MKTQYPMIPFPLIVKATDGDTEAINQILHHYRGYITKRSLRLMKD
FT                   EYGNQSMVVDEVLRGRMETRLITKILSFEIK"
FT   CDS             complement(16121..16372)
FT                   /codon_start=1
FT                   /transl_table=11
FT                   /note="ORF5"
FT                   /db_xref="UniProtKB/TrEMBL:Q57157"
FT                   /protein_id="AAB60028.1"
FT                   /translation="MSVCFIKSSFPNHLFGFHKSCFTSNRTALAKLTGVPPLHGSHVAI
FT                   LIACDGFITLGLLTVWEYHYHDKNVVAGNPAKDCFSDH"
FT   CDS             16356..16559
FT                   /codon_start=1
FT                   /transl_table=11
FT                   /gene="Xis-Tn"
FT                   /note="ORF1"
FT                   /db_xref="GOA:Q79DA1"
FT                   /db_xref="InterPro:IPR015122"
FT                   /db_xref="InterPro:IPR038148"
FT                   /db_xref="PDB:1Y6U"
FT                   /db_xref="UniProtKB/TrEMBL:Q79DA1"
FT                   /protein_id="AAB60029.1"
FT                   /translation="MKQTDIPIWERYTLTIEEASKYFRIGENKLRRLAEENKNANWLIM
FT                   NGNRIQIKRKQFEKIIDTLDAI"
FT   CDS             16641..17858
FT                   /codon_start=1
FT                   /transl_table=11
FT                   /gene="Int-Tn"
FT                   /note="ORF2"
FT                   /db_xref="GOA:P22886"
FT                   /db_xref="InterPro:IPR002104"
FT                   /db_xref="InterPro:IPR004191"
FT                   /db_xref="InterPro:IPR010998"
FT                   /db_xref="InterPro:IPR011010"
FT                   /db_xref="InterPro:IPR013762"
FT                   /db_xref="InterPro:IPR016177"
FT                   /db_xref="InterPro:IPR025269"
FT                   /db_xref="PDB:1B69"
FT                   /db_xref="PDB:1BB8"
FT                   /db_xref="PDB:1TN9"
FT                   /db_xref="PDB:2BB8"
FT                   /db_xref="UniProtKB/Swiss-Prot:P22886"
FT                   /protein_id="AAB60030.1"
FT                   /translation="MSEKRRDNRGRILKTGESQRKDGRYLYKYIDSFGEPQFVYSWKLV
FT                   ATDRVPAGKRDCISLREKIAELQKDIHDGIDVVGKKMTLCQLYAKQNAQRPKVRKNTET
FT                   GRKYLMDILKKDKLGVRSIDSIKPSDAKEWAIRMSENGYAYQTINNYKRSLKASFYIAI
FT                   QDDCVRKNPFDFQLKAVLDDDTVPKTVLTEEQEEKLLAFAKADKTYSKNYDEILILLKT
FT                   GLRISEFGGLTLPDLDFENRLVNIDHQLLRDTEIGYYIETPKTKSGERQVPMVEEAYQA
FT                   FKRVLANRKNDKRVEIDGYSDFLFLNRKNYPKVASDYNGMMKGLVKKYNKYNEDKLPHI
FT                   TPHSLRHTFCTNYANAGMNPKALQYIMGHANIAMTLNYYAHATFDSAMAEMKRLNKEKQ
FT                   QERLVA"
FT   CDS             16773..17858
FT                   /codon_start=1
FT                   /transl_table=11
FT                   /gene="Int-Tn"
FT                   /note="ORF3"
FT                   /db_xref="GOA:Q47740"
FT                   /db_xref="InterPro:IPR002104"
FT                   /db_xref="InterPro:IPR010998"
FT                   /db_xref="InterPro:IPR011010"
FT                   /db_xref="InterPro:IPR013762"
FT                   /db_xref="InterPro:IPR016177"
FT                   /db_xref="InterPro:IPR025269"
FT                   /db_xref="UniProtKB/TrEMBL:Q47740"
FT                   /protein_id="AAB60031.1"
FT                   /translation="MATDRVPAGKRDCISLREKIAELQKDIHDGIDVVGKKMTLCQLYA
FT                   KQNAQRPKVRKNTETGRKYLMDILKKDKLGVRSIDSIKPSDAKEWAIRMSENGYAYQTI
FT                   NNYKRSLKASFYIAIQDDCVRKNPFDFQLKAVLDDDTVPKTVLTEEQEEKLLAFAKADK
FT                   TYSKNYDEILILLKTGLRISEFGGLTLPDLDFENRLVNIDHQLLRDTEIGYYIETPKTK
FT                   SGERQVPMVEEAYQAFKRVLANRKNDKRVEIDGYSDFLFLNRKNYPKVASDYNGMMKGL
FT                   VKKYNKYNEDKLPHITPHSLRHTFCTNYANAGMNPKALQYIMGHANIAMTLNYYAHATF
FT                   DSAMAEMKRLNKEKQQERLVA"
FT   CDS             16884..17858
FT                   /codon_start=1
FT                   /transl_table=11
FT                   /gene="Int-Tn"
FT                   /note="ORF4"
FT                   /db_xref="GOA:Q79DA0"
FT                   /db_xref="InterPro:IPR002104"
FT                   /db_xref="InterPro:IPR010998"
FT                   /db_xref="InterPro:IPR011010"
FT                   /db_xref="InterPro:IPR013762"
FT                   /db_xref="InterPro:IPR025269"
FT                   /db_xref="UniProtKB/TrEMBL:Q79DA0"
FT                   /protein_id="AAB60032.1"
FT                   /translation="MTLCQLYAKQNAQRPKVRKNTETGRKYLMDILKKDKLGVRSIDSI
FT                   KPSDAKEWAIRMSENGYAYQTINNYKRSLKASFYIAIQDDCVRKNPFDFQLKAVLDDDT
FT                   VPKTVLTEEQEEKLLAFAKADKTYSKNYDEILILLKTGLRISEFGGLTLPDLDFENRLV
FT                   NIDHQLLRDTEIGYYIETPKTKSGERQVPMVEEAYQAFKRVLANRKNDKRVEIDGYSDF
FT                   LFLNRKNYPKVASDYNGMMKGLVKKYNKYNEDKLPHITPHSLRHTFCTNYANAGMNPKA
FT                   LQYIMGHANIAMTLNYYAHATFDSAMAEMKRLNKEKQQERLVA"
FT   misc_difference 17584
FT                   /gene="Int-Tn"
FT                   /replace="t"
FT                   /note="in ORFs 2,3,4"
FT                   /note="conflict"
FT                   /citation=[2]
XX
SQ   Sequence 18032 BP; 5909 A; 3234 C; 3754 G; 5135 T; 0 other;
     aaaatagcat aaaaatctag ttatccgcat aaaaactgga cttatcacac tttatcaagg        60
     tcaaaaccac tcaatttact actaatttac tacttatgaa tgagctttga tacgacgatt       120
     tatccttgaa aagtgaagat ataaagatac ttccaataaa atttgaatat ttaataggta       180
     gacacttcaa aaaatgaggt gtctattttt ttacccgatt ttgaaaggaa gtgaacttat       240
     gaaaacaaaa aatcaagaat caaaaggtcg ttccccactc tttaagacca tcaaacattc       300
     attcagccaa taaaaaagaa aggataggta aaaatatgga acttaaattt gtgattccca       360
     acatggaaaa aacattcggc aatttagaat ttgctggcga ggataaagtc gttcagcgaa       420
     gaatcaacgg acggctaact gtcttatcaa gaagctataa tctctattct gatgttcaaa       480
     gagcagatga tattgtggtg gtgcttcctg ctgaagctgg cgaaaaacat ttcggctttg       540
     aggaacgtgt gaagttagtc aatccacgta ttaccgcaga gggctacaaa atcggcactc       600
     gtggttttac aaattacctt ttacatgctg acgacatgat aaaagaataa agaaagagag       660
     gaaaaatgat gagattagca aatggcattg tattagataa agacacgact tttggagaat       720
     tgaaattctc tgctctacgt cgtgaagtga gaatccaaaa tgaagacggg tcggtttcag       780
     atgaaatcaa ggaacgtacc tatgacttaa aatccaaagg acaaggacgc atgattcaag       840
     taagtattcc tgccagcgtg cctttgaaag agtttgatta taacgcacgg gtggaactta       900
     tcaatcccat tgcggacacc gttgctactg ccacctatca aggagcagat gttgactggt       960
     atatcaaggc agacgatatt gtgctgacaa aggattctag ttcattcaaa gctcaaccac      1020
     aagcaaagaa agaaccgaca caagacaaat agtcgctagg tagaaaggag actttttcgc      1080
     atgaaacagc gtggtaaaag gattcgccca tctggtaaag atttagtctt tcattttacg      1140
     atagcgtcac tcctgcctgt tttcctgctg gttgtcggac tgtttcatgt gaagacaatc      1200
     cagcagatca actggcagga ttttaaccta tcacaagcag ataagattga cattccctat      1260
     ttaattatca gtttcagtgt cgcaattctt atctgcttgc tggtagcgtt tgtattcaaa      1320
     cgggttcgct atgatacggt taaacaactt taccaccgtc aaaaactggc aaagatgata      1380
     cttgaaaaca agtggtatga atctgaacag gtcaaaacag agggtttctt taaagatagt      1440
     gctggtcgta caaaggaaaa gataacctac ttccctaaaa tgtattatcg acttaaaaat      1500
     ggcttgatac agatacgggt ggaaatcacg ctgggaaaat atcaagacca actcttacac      1560
     ttggaaaaga aattagagag tggcttgtac tgtgagctga cggataaaga gttaaaggat      1620
     tcctatgtgg aatatacttt gctctatgac accatagcca gtcgtatttc tattgatgaa      1680
     gtagaagcta aagatggtaa acttcgctta atgaaaaacg tatggtggga atatgataag      1740
     ctccctcata tgttgattgc tggtggtaca ggtggcggta aaacttactt tatactgaca      1800
     ctgattgaag ccttgcttca tacagattca aaactgtata ttcttgaccc gaaaaatgct      1860
     gaccttgcgg acttaggttc tgtgatggca aatgtctact atagaaaaga agacttgctt      1920
     tcttgcattg aaacattcta tgaagaaatg atgaaacgta gtgaggaaat gaagcagatg      1980
     aagaactata agactggcaa aaattatgct tacttaggtc tcccggcaca cttcttaatc      2040
     tttgatgaat acgtcgcttt catggaaatg ctgggaacaa aagaaaacac cgcagttatg      2100
     aataagctga aacagattgt catgttaggt cgtcaagctg gcttctttct aatactggct      2160
     tgtcaacgtc cagacgcaaa atatttaggc gacggaatcc gtgatcagtt taatttcaga      2220
     gtggctttag gtcgtatgtc tgaaatgggc tatggcatga tgtttggcag tgacgtacaa      2280
     aaggatttct tcttaaagcg aatcaaaggt cgtggctatg ttgatgtagg aacaagtgtc      2340
     atatcagagt tttatactcc ccttgtacca aaaggatatg atttcttgga ggaaattaaa      2400
     aagttatcca acagcagaca gtccacgcag gcgacgtgcg aagcggaagt cgcaggtgtg      2460
     gactgatctt gctggctggt gtggcaatag ccacgccagc acttaacccc ccgtatctaa      2520
     caggggggta caaatcgaca ggaaacagtc aaaaaaacat tagaaaatcc tttggttaca      2580
     agggatttac aaaatttcag cgtatgtcaa atgggcttta aaagttgaca tacggccttt      2640
     ttgattggag ggatttttac tgaatgaaca aacttggtta cagcatttaa aagaaaaacg      2700
     cttggcttat ggactatctc aaaaccgttt agctgttgcg actggtatta caaggcagta      2760
     tctaagcgat attgaaacag gaaaagtcaa gccatcagag gatttacagc agtccctttg      2820
     ggaagctctg gaacgcttca atcccgacgc tccccttgaa atgctgtttg attatgtaag      2880
     gattcgcttt ccgacaacag acgtacagca ggtggtcgaa aacatcttac aactgaaact      2940
     gtcctatttt cttcatgagg actatggttt ctattcttat tcagagcatt atgctttagg      3000
     cgacatattc gtcctttgct cccatgaact ggacaaagga gttctggtgg aattgaaagg      3060
     tcgtgggtgc agacaatttg aaagctatct tctggcacaa caaagaagct ggtatgagtt      3120
     ctttatggac gttttggtgg ctggcggtgt gatgaaacgc cttgaccttg ccattaacga      3180
     taagacaggg attttgaata tccctgtact cactgaaaag tgccaacagg aagaatgtat      3240
     ctccgtcttc cgcagtttta aaagctatcg cagtggcgaa ctggtacgca aagaggaaaa      3300
     ggaatgtatg ggaaacaccc tctatatcgg ttcattacaa agtgaagttt atttctgtat      3360
     ctatgaaaag gactacgagc agtacaagaa aaatgatatt cccattgaag acgcagaagt      3420
     aaaaaaccgt tttgagattc gattgaaaaa tgagcgtgcc tattatgcag tccgtgattt      3480
     actcgtctat gacaatccag agcataccgc ctttaaaatt atcaatcggt atatccgttt      3540
     tgtagataaa gacgattcca aacctcgttc tgattggaaa ctgaatgaag aatgggcttg      3600
     gtttattggg aacaatcgtg aacgattaaa actaaccaca aaaccagagc cttactcctt      3660
     ccaaaggacg ctgaactggc tatctcatca agttgccccg accttaaagg ttgcgattaa      3720
     acttgatgaa atcaaccaga cgcaggttgt aaaagacatt ctcgaccatg cgaaactgac      3780
     agaccgacac aagcagattt tgaagcaaca gtcagtaaaa gaacaggacg tgataacaac      3840
     aaaaaaataa ctcaaataca aattcattga atatagagag gagaacattt ttatgaattt      3900
     tggacaaaac ctttataact ggtttctatc aaacgctcaa tcactggtgc ttttagcaat      3960
     cgttgtgatt ggcttgtatc ttggcttcaa gcgtgagttt agcaaactga ttggcttttt      4020
     aattattgcg attattgcgg ttggcttagt cttcaacgct gctggagtaa aagacatttt      4080
     actagagcta ttcaatcgca ttattggtgc ttaaataaaa ccgttctttt gtggaatata      4140
     agtggttttc ttatgttccg caaaggaatg gtacaccaaa cgaagtgcgg tagggatttt      4200
     tgaatctcta caaagaaagg acgtgaatat atggacgata tgcaagtcta tattgcgaat      4260
     ttaggcaaat acaatgaggg cgaattggtc ggtgcgtggt ttacctttcc cattgacttt      4320
     gaggaagtca aagagaaaat cggcttgaat gatgaatatg aggaatacgc cattcatgac      4380
     tacgagttac cctttacggt tgacgaatac acttccattg gcgaactcaa tcgactatgg      4440
     gaaatggtat cggaattacc cgaagaatta caatcggagc tatctgctct gctcactcat      4500
     ttttcaagca ttgaagaact aagcgaacat caagaggata ttatcattca ttccgattgt      4560
     gatgatatgt atgacgtggc acgctactac attgaagaaa cgggtgcttt aggcgaagta      4620
     ccagctagtc ttcaaaacta tattgattat caagcctatg gtcgggattt agacctttca      4680
     ggaacgttta tctcaaccaa tcatgggatt tttgaaatcg tctattaaat ctgtcggtac      4740
     attactactg gcagattttc tattttacgg ggtggctcaa tcagctaccc ctatttttta      4800
     tgaaaggatt gattacatga agaaaatacg aagctatacc agtatctggt ctgtggaaaa      4860
     ggtactgtat tctatcaatg attttagact tccgtttccc ataaccttta cgcaaatgac      4920
     atggtttgtc gtgtcactct ttgcagtgat gatacttggc aacttgcccc ctctttccat      4980
     gatagaggga gcatttctca aatactttgg gattcctgtg gctttcacat ggtttatgtc      5040
     tacaaaaact tttgatggta aaaagcctta tggatttttg aagtctgtca ttgcttatgc      5100
     actgcgacca aagctgacct atgcaggaaa aaaagtaacg cttggcagaa accagccaca      5160
     agaagccatt acagcagtta ggagtgaatt ttatggcata tccaattaaa tacattgaaa      5220
     acaatctcgt ctggaataaa gacggggaat gttatgctta ctatgagctt gttccttaca      5280
     attactcatt tctaagtcca gaacagaaaa tacaagtgca tgattctttc agacagctta      5340
     tcgcacaaaa tcgtgatggc aaaattcatg ctttacaaat cagtacagaa tccagcatac      5400
     gttctgcaca agagcgttcc aaaaatgaag tcactggcaa gctcaaagcg gttgcctatg      5460
     acaaaatcga ccaacagaca gacgctttaa tatccatgat tggcgaaaat caagtgaact      5520
     accgtttctt tatcggcttt aagttgcttc tcaacgatca ggagttttct atgaaaagtc      5580
     ttaccgttga agcaaaaaat gctttgtctg attttgtcta tgatgtgaac cataagctga      5640
     tgggcgattt tgttagtatg agtaatgatg aaatcctgcg ttttcagaag atggaaaagc      5700
     tcttagaaaa taaaatctct cgtcgtttca aaatccgcag gttagataag gacgacttcg      5760
     gctatctgat tgaacacctt tacggacaga caggcactgc ctatgaagag tatgagtacc      5820
     atctatcaaa gaaaaagctg gataatgaaa cgctgattaa atactatgac ttgattaagc      5880
     ctactcgctg tttggtggaa gaaaaacagc gatatttgaa aatccagcag gaagatgaaa      5940
     ccgtctatgt agcttacttt accattaaca gcattgtcgg agaactggac ttcccgtcct      6000
     ctgaaatctt ctactaccag caacagcaat ttacattccc gattgatacg tcaatgaatg      6060
     tggaaattgt agcgaatcgt aaagccctat ctactgtccg caataaaaag aaagaactga      6120
     aagacttgga taaccacgct tggcaaagtg ataatgaaac cagctccaat gtggcggaag      6180
     ctctggaaag tgtgaatgag ctggaaacca atttagacca aagcaaggaa tctatgtaca      6240
     agctgtctta tgtggtaagg gtatcagcaa atgatcttga cgaactcaaa cgtcgttgta      6300
     atgaagtgaa agatttttat gacgatttaa gcgtaaaact ggtacgacca tttggggata      6360
     tgctcggctt acatgaagaa tttttacctg ccagcaagcg ttatatgaat gattatattc      6420
     aatacgtgac ctctgatttc ctcgctggtt taggttttgg tgctactcaa atgctggggg      6480
     aaaatgaggg gatttatgtt ggctacagct tagatactgg acgcaatgtc tatctgaaac      6540
     ctgctcttgc cagtcaaggg gttaagggtt cagtaaccaa tgcgttagcg tcggcttttg      6600
     ttggttcgct gggtggtggt aaatcctttg cgaataacct tatcgtctat tatgcggtgc      6660
     tttatggggc acaagcagtg attgtagacc caaaagcaga acgtggcaga tggaaagaaa      6720
     ccttgccaga gatttcccat gaaatcaata tcgtcactct gacttctgat gagaaaaaca      6780
     aaggcttact tgacccttat gtgattatga aaaatcccaa agattctgaa tcactggcta      6840
     ttgatattct gacattcctt acggggattt cctctcgtga tggggaacgc ttcccaatcc      6900
     ttagaaaagc cattcgtgca gtaaccaata gtgaagtacg agggttgatg aaagtgattg      6960
     aggaattacg ggttgagaat acgccactaa gtaccagtat agccgaccat atcgaaagtt      7020
     ttacagacta tgactttgca catttattat tcagtaatgg ttatgtggag cagtctatca      7080
     gcttagaaaa acaactgaac attatacagg ttgcggactt ggtacttccc gacaaggaaa      7140
     cttcctttga ggaatatacc actatggagc ttttatccgt tgctatgctg attgtcatta      7200
     gtacctttgc tttagacttt atccatacag accgaagcat tttcaagatt gtagatttag      7260
     acgaagcatg gagcttttta caggtagcac aaggaaaaac actatctatg aagctggttc      7320
     gggctggtcg tgctatgaac gctggggtat atttcgtgac ccaaaataca gacgacctct      7380
     tagatgaaaa actgaaaaat aacctcggct taaaatttgc atttcgttcc actgacctta      7440
     acgagattaa aaagacctta gccttttttg gtgtagaccc agaggacgaa aacaatcaga      7500
     agcgattgcg tgatttggaa aacgggcaat gccttatcag tgatttatat ggtcgtgtcg      7560
     gtgtgataca gttccaccct gtatttgaag aactgctcca tgcctttgat accagaccac      7620
     ctgtgcgaaa agaggtgtaa atgtgaaacc atcaatagta aacagaataa aatcaaactg      7680
     gacgctgaaa cgtctaggta aagtggcaat gacagtggct ttcacacttg tgattgccat      7740
     ttttctttta gccatgctgg gaacggtggt tcaagctgcg ggcttggtag atgatacggt      7800
     caatgtggca aatgaataca gccgataccc acttgaaaac tatcaactgg atttttatgt      7860
     ggataatagc tggggctggc ttccgtggaa ctggtcggac gggattggaa aacaggtcat      7920
     gtatggacta tatgccatta ccaattttat ttggacaatc agtttgtatg tttccaatgc      7980
     gacaggttac ttagtacagg aagcctattc cttagacttc atttccgcta cagcagattc      8040
     cattggtaag aatatgcaga ccttagctgg tgtgagtgca aacggatttt caacagaggg      8100
     tttctatgtt ggattcctct tactcttgat tttggttctt ggggtttatg ttgcctatac      8160
     gggactgata aagagagaaa ccacaaaggc aattcatgcc attatgaatt ttgtgctggt      8220
     gtttatccta tcggcttcct ttattgccta cgctcccgac tacattaaaa aaatcaatga      8280
     cttttcatca gacatcagta atgccagttt atcacttggc acgaagattg tcatgcccca      8340
     ttccgatagt caaggcaagg acagcgtgga cttaatcaga gatagcctgt tttccataca      8400
     ggttcagcaa ccgtggctac tgcttcaata caacagttca gacattgaaa gtatcggtat      8460
     tgaccgtgtg gaaagcctgc tctccaccag cccagattcc aacaatggcg aagacagaga      8520
     aaaaattgtt gcggaagaaa ttgaagacag aagcaatacc aatctaacca ttacaaagac      8580
     cattaaccgt ttaggtacag tcttcttcct atttgtcttc aatattggga tttccatatt      8640
     tgtattccta ttaacaggaa tcatgatttt ctcgcaggta ctttttatca tctatgctat      8700
     gtttctgcct gtgagcttta ttttaagcat gattccatca tttgatggta tgtcaaaacg      8760
     agccataaca aagctcttta ataccatttt gacacgagct ggaatcacat tgattattac      8820
     gacagcattt agtatttcaa ccatgctcta taccttatcg gctggttatc cgttcttttt      8880
     gattgctttt ctacagattg tgacctttgc aggaatctac ttcaagctgg gcgatttaat      8940
     gagtatgttt tctctacaga gtaacgattc tcaaagtgtg ggaagtcgtg tgatgagaaa      9000
     acctcgtatg cttatgcacg ctcacatgca ccgtctacag cggaaacttg gacgttccat      9060
     gactactcta ggggctgggt ctgccattgt tacaggtaaa aaaggacagt cgggttcggg      9120
     gagttctgca aggacacaag cagatcactc ccgaccagac ggaaaggaaa aatcaacact      9180
     tggaaaacgt atcggtcaaa ccatcggtac agtagctgat accaaagaca gaatggtaga      9240
     cactgctagt ggtttgaaag aacaggttaa agatttgccg accaatgcaa gatatgcagt      9300
     atatcaagga aaatccaaag taaaagagaa tgtccgtgat ttaaccagta gtatttctca      9360
     aaccaaagcg gacagagcca gtggacgcaa ggaacagcag gaacaaaggc gaaaaaccat      9420
     tgcgaagcgt cgctctgaaa tggaacaggt caaacagaaa aaacagcctg cttcttctgt      9480
     tcatgaaaga ccgactacaa gacaagaaca atatcatgat gaacagacct caaaacagtc      9540
     taatattcag acttcatata aggaatctca acaagccaaa caagagcgtc cagcagttaa      9600
     gtccgatttt tcaagtccaa aagtggaacg caaggcaata ccgttcaaga aaaaaccgtt      9660
     caaaagccag caacttcaac cactacagca gatagaactt cacaacgtcc aatcacaaaa      9720
     gaacgtccgt ctactgttca aagagtacca ctacaaaata caagaagtag accaccaatc      9780
     aaaaccgcca ccattaagaa agtcggtaag aaaccatgaa gttgaaaact ttagtgattg      9840
     gtggttctgg attattcttg atggtcttct cactgcttct gtttgttgcc attttatttt      9900
     cagatgaaca ggacagcgga atttccaata ttcattatgg aggtgtgaat gtttccgcag      9960
     aagtgctggc tcataagcct atggtagaaa aatatgccaa agaatatggc gttgaagaat     10020
     atgtcaacat acttcttgcg attatacagg tggaatcggg cggtactgcg gaagatgtta     10080
     tgcagtcctc ggaatccctc ggtcttccac ctaattcatt gagtacagaa gaatccatta     10140
     agcaaggtgt gaagtatttc agtgaattat tagccagtag cgaaaggctc agtgtagatt     10200
     tagaatcggt tatccagtcc tacaattatg gtggtggttt cttagggtat gtggctaatc     10260
     gtggaaataa atataccttt gaactggctc aaagtttctc aaaagagtat tcaggtggcg     10320
     aaaaagtgtc ttaccccaat cccatagcca tacctatcaa tgggggctgg cgatacaact     10380
     atggcaatat gttttatgtg caactggtaa cgcagtatct tgtcacaaca gagtttgatg     10440
     atgatacggt acaagccatc atggacgaag cactgaaata tgagggctgg cgatacgttt     10500
     acggtggagc ttccccgact acttcttttg attgtagcgg actgacacaa tggacgtatg     10560
     gaaaagctgg aattaactta ccacgaaccg cacaacagca atatgatgtg acccagcata     10620
     tcccactatc ggaagcacaa gctggcgatt tggttttctt tcattctacc tataacgctg     10680
     gctcttatat tactcatgtt gggatatacc ttggcaataa ccgtatgttt catgcaggcg     10740
     acccaatcgg ttatgccgac ttaacaagcc cctactggca acagcattta gtgggagcag     10800
     gacgaatcaa acaatgagaa aggaagattt aatgatgaaa tttagaaaaa atcagaataa     10860
     agaaaaacag ataccaaagg aaaagaaacc tcgtgtctat aaggtcaatc ctcataaaaa     10920
     ggttgtgatt gccttgtggg tacttttagg gcttagtttc agctttgcga tattcaagca     10980
     ctttacagct atagatactc atactattca cgaaacaact atcatagaaa aggaatacgt     11040
     tgatactcat catgtagaaa attttgtaga gaactttgcg aaagtctact attcatggga     11100
     gcaatccgat aagtccattg ataatcgaat ggaaagtcta aaaggctatc tgacagatga     11160
     acttcaagct ctcaatgttg atacagtacg caaagatatt cctgtatcgt cttctgtaag     11220
     aggatttcag atatggacgg tagagccaac tggcgacaat gagtttaatg taacctacag     11280
     tgtagaccag ctcattacag agggagaaaa tacaaagacc gtccactctg cttatatagt     11340
     gagtgtctat gtagatggtt ctggaaatat ggtactggtt aagaatccga ccattaccaa     11400
     catacctaag aaatcaagtt ataaaccaaa agccattgaa agtgagggga cggttgattc     11460
     cattacaacc aatgaaatca atgagttttt aacgacgttc ttcaagctct atcctacagc     11520
     gacagccagt gaactttcct actatgtgaa tgacgggata ttaaaaccaa tcggaaaaga     11580
     gtacatcttt caagaactgg taaatcctat tcacaatcgt aaggataatc aagtcacggt     11640
     atcgctgaca gtggagtata tcgaccagca gaccaaagca acgcaggtat ctcaatttga     11700
     tttggtactt gaaaagaacg ggagtaattg gaagattata gaataacaaa tattggtaca     11760
     ttattacagc tattttgtaa tcacgtactc tctttgataa aaaattggag attcctttac     11820
     aaatatgctc ttacgtgcta ttatttaagt atctatttaa aaggagttaa taaatatgcg     11880
     gcaaggtatt attaaataaa ctgtcaattt gatagcggga acaaataatt ggatgtcctt     11940
     ttttaggagg gcttagtttt ttgtacccag tttaagaata cctttatcat gtgattctaa     12000
     agtatccgga gaatatctgt atgctttgta tgcctatggt tatgcataaa aatcccagtg     12060
     ataagagtat ttatcactgg gatttttatg cccttttggg cttttgaatg gaggaaaatc     12120
     acatgaaaat tattaatatt ggagttttag ctcatgttga tgcaggaaaa actaccttaa     12180
     cagaaagctt attatataac agtggagcga ttacagaatt aggaagcgtg gacaaaggta     12240
     caacgaggac ggataatacg cttttagaac gtcagagagg aattacaatt cagacaggaa     12300
     taacctcttt tcagtgggaa aatacgaagg tgaacatcat agacacgcca ggacatatgg     12360
     atttcttagc agaagtatat cgttcattat cagttttaga tggggcaatt ctactgattt     12420
     ctgcaaaaga tggcgtacaa gcacaaactc gtatattatt tcatgcactt aggaaaatgg     12480
     ggattcccac aatctttttt atcaataaga ttgaccaaaa tggaattgat ttatcaacgg     12540
     tttatcagga tattaaagag aaactttctg ccgaaattgt aatcaaacag aaggtagaac     12600
     tgtatcctaa tgtgtgtgtg acgaacttta ccgaatctga acaatgggat acggtaatag     12660
     agggaaacga tgacctttta gagaaatata tgtccggtaa atcattagaa gcattggaac     12720
     tcgaacaaga ggaaagcata agatttcaga attgttctct gttccctctt tatcatggaa     12780
     gtgcaaaaag taatataggg attgataacc ttatagaagt tattactaat aaattttatt     12840
     catcaacaca tcgaggtccg tctgaacttt gcggaaatgt tttcaaaatt gaatatacaa     12900
     aaaaaagaca acgtcttgca tatatacgcc tttatagtgg agtactacat ttacgagatt     12960
     cggttagagt atcagaaaaa gaaaaaataa aagttacaga aatgtatact tcaataaatg     13020
     gtgaattatg taagattgat agagcttatt ctggagaaat tgttattttg caaaatgagt     13080
     ttttgaagtt aaatagtgtt cttggagata caaaactatt gccacagaga aaaaagattg     13140
     aaaatccgca ccctctacta caaacaactg ttgaaccgag taaacctgaa cagagagaaa     13200
     tgttgcttga tgcccttttg gaaatctcag atagtgatcc gcttctacga tattacgtgg     13260
     attctacgac acatgaaatt atactttctt tcttagggaa agtacaaatg gaagtgatta     13320
     gtgcactgtt gcaagaaaag tatcatgtgg agatagaact aaaagagcct acagtcattt     13380
     atatggagag accgttaaaa aatgcagaat ataccattca catcgaagtg ccgccaaatc     13440
     ctttctgggc ttccattggt ttatctgtat caccgcttcc gttgggaagt ggaatgcagt     13500
     atgagagctc ggtttctctt ggatacttaa atcaatcatt tcaaaatgca gttatggaag     13560
     ggatacgcta tggttgtgaa caaggattgt atggttggaa tgtgacggac tgtaaaatct     13620
     gttttaagta tggcttatac tatagccctg ttagtacccc agcagatttt cggatgcttg     13680
     ctcctattgt attggaacaa gtcttaaaaa aagctggaac agaattgtta gagccatatc     13740
     ttagttttaa aatttatgcg ccacaggaat atctttcacg agcatacaac gatgctccta     13800
     aatattgtgc gaacatcgta gacactcaat tgaaaaataa tgaggtcatt cttagtggag     13860
     aaatccctgc tcggtgtatt caagaatatc gtagtgattt aactttcttt acaaatggac     13920
     gtagtgtttg tttaacagag ttaaaagggt accatgttac taccggtgaa cctgtttgcc     13980
     agccccgtcg tccaaatagt cggatagata aagtacgata tatgttcaat aaaataactt     14040
     agtgtatttt atgttgttat ataaatatgg tttcttgtta aataagatga aatatttttt     14100
     aataaagatt tgaattaaag tgtaaaggag gagatagtta ttataaacta caagtggata     14160
     ttgtgtcctg tatgtggaaa taaaacacga ttaaagataa gggaagatac tgaattaaaa     14220
     aaattccccc tctattgtcc gaaatgcaga caagaaaatt taattgaaat aaagcagttc     14280
     aaagtaactg tgattacaga gccagacgca aagacgcaga gccgataaaa tgagattaat     14340
     acaatctcat tttatcggct ctttccgtta tgtatggatt cttttaatta gtcttcgatg     14400
     tttcttgctt cgttgatacc gctggctaaa gattccatta aggatagttc tttgtctgta     14460
     aagctatcca tgtatttctc tatctgtaat cgtcgggtgc tttttaccaa gttattagca     14520
     ggtaagaaaa attcatcaac ggaaacatga agtaacgata caaggtcata aagaacttgt     14580
     atgctggggt gttgcccttt attttcaata ttagttaagt accgtgggtc aatttcaatc     14640
     aatgctccca cttgttcacg agttaaacct cgttgcaatc gagcttcttt aatggctaaa     14700
     ccaaaggctc taaaatcata tttatcttct tttttacgca tagtagacca cctctataca     14760
     ttttattgtt cctactgaat taaaaacagg tatagaaaaa cgtgttatat ggtttatagg     14820
     tttatattta ataaaaagca ctactaaacg ccaataaaaa aaaccgttat atggtagtgc     14880
     tatttacgct gttaaaatat tgtatattac ttccaaatgg cggtttgttg gaggtcaacg     14940
     tcgccatgaa gtacatcata tacaataaat ttccttacat tgggttcttg tcaaaaaaag     15000
     tcgtctatct gcaatagata agtacgtcca ccaatgtggt tttataaatc atatagatag     15060
     aataacagaa gcatgtaaac agagaaataa atctgtttat atgctttttt ggctattcag     15120
     aactttttta caaagtttat ttatcagtaa tgcaacaaat ccccctttca cattgggact     15180
     aagagtgaaa ggagataaac gagcaaggct cacttccttt cctagacaga aagggggtga     15240
     gaaacatgaa accatcttct tttcagacca caatagaaaa tcagtttgac tatatctgta     15300
     aacgtgctat ggaagacgag cgaaagaatt atatgcttta tctttcaagg attgcaaagc     15360
     gtgaggtgtc cttttcggat gttggcgatt atcttgttag ccagtttgcg acaacagata     15420
     actattcaac tgactttcag atttttacac tcaatgggtt atcagtaggc gttgaaaatg     15480
     atttgttgag tgaagcatta cgtgagttgc cagacaagaa acgtgaaatt ctactgctgt     15540
     tttactttat ggacatgagc gattcagaaa ttgcagacct gttgaaattg aaccgttcta     15600
     ctgtctatcg gcatagaacc agtggactag ccttaattaa aaagtttatg gaggaatttg     15660
     aagaatgaaa acacaatatc ctatgattcc ctttcctctc attgtaaagg caacagatgg     15720
     cgataccgaa gcgattaacc agattctaca tcattacaga gggtacataa cgaagcgttc     15780
     cctacgactt atgaaagatg aatatggcaa tcaaagtatg gtcgttgatg aagtcttacg     15840
     tggaagaatg gaaaccagac tgattacaaa gattttgtca tttgaaatta agtaatatcc     15900
     tctctccttt cgtggaagcg tgctaaacca ttccacgctt cccgaacagg gaggtttgtt     15960
     attccaccaa agcatattga gctttcaatg tgttttgata ggctaacgag ccattgttct     16020
     ttgaaaactg aataaaagta atcgaatacg tttcgataag aaaagagcca acggaactaa     16080
     ccgccatgac ctatcttata aagatagcga gcgattcatg ttagtgatcc gagaagcaat     16140
     ctttagcagg attgcctgca acgacattct tatcgtgata atgatactcc catacagtca     16200
     atagtccgag cgtgataaaa ccgtcgcagg caatgagtat ggctacatga gaaccatgca     16260
     ggggtggaac tcccgtgagc tttgctaaag ctgttcgatt gctggtaaaa caacttttat     16320
     gaaatccaaa taagtgattt ggaaaggagg attttatgaa gcagactgac attcctattt     16380
     gggaacgtta taccctaacc attgaagaag cgtcaaaata ttttcgtatt ggcgaaaaca     16440
     agctacgacg cttggcagag gaaaataaaa atgcaaattg gctgattatg aatggcaatc     16500
     gtattcagat taaacgaaaa caatttgaaa aaattataga tacattggac gcaatctagc     16560
     gtcgccaaag ggtcttgtat atgataaaat agtattaagt cgtatcaagg ctctttccat     16620
     aaaggaaagg agcaaatgcc atgtcagaaa aaagacgtga caatagaggt cgaatcttaa     16680
     agactggaga gagccaacga aaagacggaa gatacttata caaatatata gattcatttg     16740
     gagaaccgca atttgtttac tcgtggaaac ttgtggctac agaccgagta ccagcaggaa     16800
     agcgtgattg tatctcactt agagagaaaa tcgcagagtt acagaaagac attcatgatg     16860
     gtattgatgt tgtaggaaag aaaatgacac tctgccagct ttacgcaaaa cagaacgctc     16920
     aaagaccaaa ggttagaaaa aacactgaaa ctggacgcaa atatcttatg gatattttga     16980
     agaaagacaa gttaggtgta agaagtattg acagtattaa gccatcagac gctaaagaat     17040
     gggctattag aatgagtgaa aatggttatg cttatcaaac catcaataac tacaaacgtt     17100
     ctttaaaggc ttcattctat attgctatac aagatgattg tgttcggaag aatccatttg     17160
     actttcaact gaaagcagtt cttgatgatg atactgtccc taagaccgta ctaacagaag     17220
     aacaggaaga aaaactgtta gcctttgcaa aagctgataa aacctacagc aaaaattatg     17280
     atgaaattct gatactctta aaaacaggtc ttcgtatttc agagtttggt ggtttgacac     17340
     ttccagattt agattttgag aatcgtcttg tcaatataga ccatcagcta ttgagagata     17400
     ctgaaattgg gtactacatt gaaacaccaa agaccaaaag tggcgaacgt caagttccta     17460
     tggttgaaga agcctatcaa gcatttaagc gagtgttagc gaatcgaaag aatgataagc     17520
     gtgttgagat tgatggatat agtgatttcc tctttcttaa tagaaagaac tatccaaaag     17580
     tggcaagtga ttacaacggc atgatgaaag gtcttgttaa gaaatacaat aagtataacg     17640
     aggataaatt gccacacatc actccacata gtttgcgaca tacattctgt accaactatg     17700
     caaatgcagg aatgaatcca aaggcattac agtacattat gggacatgct aatatagcca     17760
     tgacgctgaa ctattacgca catgcaacat tcgattctgc aatggcagaa atgaaacgct     17820
     tgaataaaga gaagcaacag gagcgtcttg ttgcttagta gtacaaatga atttactact     17880
     tatttaccac ttctgacagc taagacatga ggaaatatgc aaagaaacgt gaagtatctt     17940
     cctacagtaa aaatactcga aagcacatag aataaggctt tacgagcatt taagaaaata     18000
     taaaaagata attagaaatt tatactttgt tt                                   18032
//