ID AF074705; SV 2; linear; genomic DNA; STD; PRO; 15023 BP. XX AC AF074705; XX DT 05-AUG-1998 (Rel. 56, Created) DT 15-APR-2005 (Rel. 83, Last updated, Version 5) XX DE Pseudomonas aeruginosa dihydroaeruginoic acid synthetase (pchE), pyochelin DE synthetase (pchF), reductase (pchG), ABC transporter (pchH), and ABC DE transporter (pchI) genes, complete cds. XX KW . XX OS Pseudomonas aeruginosa OC Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales; OC Pseudomonadaceae; Pseudomonas. XX RN [1] RP 1-15023 RX PUBMED; 9846750. RA Reimmann C., Serino L., Beyeler M., Haas D.; RT "Dihydroaeruginoic acid synthetase and pyochelin synthetase, products of RT the pchEF genes, are induced by extracellular pyochelin in Pseudomonas RT aeruginosa"; RL Microbiology (Reading, Engl.) 144(Pt 11):3135-3148(1998). XX RN [2] RP 1-15023 RX DOI; 10.1128/JB.183.3.813-820.2001. RX PUBMED; 11208777. RA Reimmann C., Patel H.M., Serino L., Barone M., Walsh C.T., Haas D.; RT "Essential PchG-dependent reduction in pyochelin biosynthesis of RT Pseudomonas aeruginosa"; RL J. Bacteriol. 183(3):813-820(2001). XX RN [3] RP 1-15023 RA Reimmann C., Serino L., Beyeler M., Haas D.; RT ; RL Submitted (26-JUN-1998) to the INSDC. RL Laboratoire de Biologie Microbienne, Universite de Lausanne, Batiment de RL Biologie, Lausanne, VD 1015, Switzerland XX RN [4] RC Sequence update by submitter RP 1-15023 RA Reimmann C., Patel H.M., Serino L., Barone M., Walsh C.T., Haas D.; RT ; RL Submitted (03-JUL-2000) to the INSDC. RL Laboratoire de Biologie Microbienne, Universite de Lausanne, Batiment de RL Biologie, Lausanne, VD 1015, Switzerland XX DR MD5; c73aa22f9c43ead4a6d7ea60416b551f. DR EuropePMC; PMC94946; 11208777. DR StrainInfo; 154131; 0. XX CC On Feb 6, 2001 this sequence version replaced gi:3386352. XX FH Key Location/Qualifiers FH FT source 1..15023 FT /organism="Pseudomonas aeruginosa" FT /strain="PAO1" FT /mol_type="genomic DNA" FT /db_xref="taxon:287" FT CDS 805..5121 FT /codon_start=1 FT /transl_table=11 FT /gene="pchE" FT /product="dihydroaeruginoic acid synthetase" FT /note="peptide synthetase" FT /db_xref="GOA:O85739" FT /db_xref="InterPro:IPR000873" FT /db_xref="InterPro:IPR001242" FT /db_xref="InterPro:IPR006162" FT /db_xref="InterPro:IPR009081" FT /db_xref="InterPro:IPR010071" FT /db_xref="InterPro:IPR020806" FT /db_xref="InterPro:IPR020845" FT /db_xref="InterPro:IPR023213" FT /db_xref="InterPro:IPR029063" FT /db_xref="InterPro:IPR036736" FT /db_xref="InterPro:IPR042099" FT /db_xref="UniProtKB/TrEMBL:O85739" FT /protein_id="AAC83656.1" FT /translation="MDLPPDSRTALRDWLTEQLADLLGEPLADVRALADDDDLLGCGLD FT SIRLMYLQERLRARGSTLDFAQLAQRPCLGAWLDLLACADRLSAPATVALPTAQDRDQP FT FELSSVQQAYWLGRGAGEVLGNVSCHAFLEFRTRDVDPQRLAAAAECVRQRHPMLRARF FT LDGRQQILPTPPLSCFDLQDWRTLQVDEAERDWQALRDWRAHECLAVERGQVFLLGLVR FT MPGGEDRLWLSLDLLAADVESLRLLLAELGVAYLAPERLAEPPALHFADYLAHRAAQRA FT EAAARARDYWLERLPRLPDAPALPLACAPESIRQPRTRRLAFQLSAGESRRLERLAAQH FT GVTLSSVFGCAFALVLARWSESAEFLLNVPLFDRHADDPRIGEVIADFTTLLLLECRMQ FT AGVSFAEAVKSFQRNLHGAIDHAAFPALEVLREARRQGQPRSAPVVFASNLGEEGFVPA FT AFRDAFGDLHDMLSQTPQVWLDHQLYRVGDGILLAWDSVVGLFPEGLPETMFEAYVGLL FT QRLCDSAWGQPADLPLPWAQQARRALLNGQPACATARTLHRDFFLRAAEAPDADALLYR FT DQRVTRGELAERALRIAGGLREAGVRPGDAVEVSLPRGPQQVAAVFGVLAAGACYVPLD FT IDQPPARRRLIEEAAGVCLAITEEDDPQALPPRLDVQRLLRGPALAAPVPLAPQASAYV FT IYTSGSTGVPKGVEVSHAAAINTIDALLDLLRVNASDRLLAVSALDFDLSVFDLFGGLG FT AGASLVLPAQEQARDAAAWAEAIQRHAVSLWNSAPALLEMALSLPASQADYRSLRAVLL FT SGDWVALDLPGRLRPRCAEGCRLHVLGGATEAGIWSNLQSVDTVPPHWRSIPYGRPLPG FT QAYRVVDTHGRDVPDLVVGELWIGGASLARGYRNDPELSARRFVHDAQGRWYRTGDRGR FT YWGDGTLEFLGRVDQQVKVRGQRIELGEVEAALCAQAGVESACAAVLGGGVASLGAVLV FT PRLAPRAEGSMDLPAAQPFAGLAEAEAVLTREILGALLEAPLELDDGLRRRWLDWLADS FT AASALPSLDEALRRLGWQAAGLTAMGNALRGLLAGEQAPAALLLDPWLAPQAVAARLPD FT GREALARLLEALPTPAAGERLRVAVLDTRAGLWLDQGMASLLRPGLELTLFERSRVLLD FT AAATRLPERIVVQALDDGLLPAEHLGRYDRVISFAALHAYEASREGLALAAALLRPQGR FT LLLVDLLCESPLALLGAALLDDRPLRLAELPSLLADLAAAGLAPRCLWRSERIALVEAL FT APGLGLDAAALQAGLEQRLPQAMRPERLWCLPSLPLNGNGKVDRRRLAESMTRALGECR FT HEPSAEEPLEAHEQALAECWEAVLKRPVRRREASFFSLGGDSLLATRLLAGIRERFGVR FT LGMADFYRQPTLAGLARHLQVQTVEIEETQLEEGVL" FT CDS 5118..10547 FT /codon_start=1 FT /transl_table=11 FT /gene="pchF" FT /product="pyochelin synthetase" FT /note="peptide synthetase" FT /db_xref="GOA:O85740" FT /db_xref="InterPro:IPR000873" FT /db_xref="InterPro:IPR001031" FT /db_xref="InterPro:IPR001242" FT /db_xref="InterPro:IPR006162" FT /db_xref="InterPro:IPR009081" FT /db_xref="InterPro:IPR010071" FT /db_xref="InterPro:IPR013217" FT /db_xref="InterPro:IPR020459" FT /db_xref="InterPro:IPR020845" FT /db_xref="InterPro:IPR023213" FT /db_xref="InterPro:IPR029058" FT /db_xref="InterPro:IPR029063" FT /db_xref="InterPro:IPR036736" FT /db_xref="InterPro:IPR041464" FT /db_xref="InterPro:IPR042099" FT /db_xref="UniProtKB/TrEMBL:O85740" FT /protein_id="AAC83657.1" FT /translation="MSLGELLETCRSRRIELWSEAGRLRYRAPQGALDAGLAERLRAER FT EALLEHLEGGPGWRAEPDMAHQRFPLTPVQAAYVLGRQAAFDYGGNACQLYAEYDWPAD FT TDPARLEAAWNAMVERHPMLRAVIEDNAWQRVLPEVPWQRLTVHACAGLDEAAFQAHLE FT RVRERLDHACAALDQWPVLRPELSIGRDACVLHCSVDFTLVDYASLQLLLGEWRRRYLD FT PQWTAEPLEATFRDYVGVEQRRRQSPAWQRDRDWWLARLDALPGRPDLPLRVQPDTRST FT RFRHFHARLDEAAWQALGARAGEHGLSAAGVALAAFAETIGRWSQAPAFCLNLTVLNRP FT PLHPQLAQVLGDFTALSLLAVDSRHGDSFVERARRIGEQMFDDLDHPTFSGVDLLRELA FT RRRGRGADLMPVVFTSGIGSVQRLLGDGEAPRAPRYMISQTPQVWLDCQVTDQFGGLEI FT GWDVRLGLFPEGQAEAMFDDFVGLLRRLAQSPRAWTDGDATEPVEAPPQALPGSARSIA FT AGFAERALLTPDATAIHDAAGSYSYRQVAQHASALRRVLEAHGAGRGRRVAVMLPKSAA FT QLVAVIGILQAGAAYVPVDIRQPPLRRQAILASAEVVALVCLESDVPDVGCACVAIDRL FT AADSAWPPPPAAEVAADDLAYVIYTSGSTGTPKGVMLSHAAVSNTLLDINQRYGVDAND FT RVLGLAELSFDLSVYDFFGATAAGAQVVLPDPARGSDPSHWAELLERHAITLWNSVPAQ FT GQMLIDYLESEPQRHLPGPRCVLWSGDWIPVSLPTRWWRRWPDSAAVQPGRRTEAAIWS FT IEQPIRPQHTELASIPYGRALRGQSVEVLDARGRRCPPGVRGEIHIGGVGLALGYAGDP FT QRTAERFVRHPDGRRLYRTGDLGRYLADGSIEFLGREDDQVKIRGHRIELAELDAALCA FT HPQVNLAATVVLGETHERSLASFVTLHAPVEAGEDPRTALDAVRQRAAQALRRDWGSEE FT GIAAAVAALDRACLASLAAWLAGSGLFASATPLDLATLCQRLGIAEARQRLLRHWLRQL FT EEGGYLRAEGEGWLGCAERPAQSPEDAWTAFAGCAPAALWPAELVAYLRDSAQSLGEQL FT AGRISPAALMFPQGSARIAEAMYSQGLHAQALHEAMAEAIAAIVERQPQRRWRLLELGA FT GTAAASRTVIARLAPLVQRGAEVDYLFTDVSSYFLAAARERFADQPWVRFGRFDMNGDL FT LDQGVAPHSVDILLSSGALNNALDTPALLAGLRELLSADAWLVIQELTREHNEISVSQS FT LMMENPRDLRDERRQLFVHTGQWLEWLAAQGGDLACGVVPPGSALDLLGYDVLLARCKT FT DRARLEPAELLAFVEARVPRYMLPAQLRVLERLPVTGNGKIDRKALTGFARQPQADLRH FT GVAQAPADELENALLALWREVLDNPSLGVEQDFFGAGGDSLLIAQLIARLRERLESARR FT HPFDRLLRWALSQPTPRGLAERLRSAPEEGRGPALAAARGVAPAPAGMSRAPLAEGAVA FT LDPLVRLVPGEGVPRVLVHEGLGTLLPYRPLLRALGEGRPLLGLAVHDSDAYLAIPAEH FT LNACLGRRYAEALHRAGLREVDLLGYCSGGLVALETAKSLVQRGVRVRQLDIVSSYRIP FT YRVDDERLLLFSFAATLGLDTAALGFPAPERLGQAVQAALAQTPERLVAEALAGLPGLA FT DLVALRGRVLQAASGSADAVSVERDTLYRLFCHSVRASQAEAPEPYVGALRLFVPDAGN FT PLVPRYAEALETQWRAAALGACGIHEVPGGHFDCLGEALAQSLSKPMPEEASR" FT CDS 10544..11593 FT /codon_start=1 FT /transl_table=11 FT /gene="pchG" FT /product="reductase" FT /note="11000" FT /db_xref="GOA:G3XCL0" FT /db_xref="InterPro:IPR000683" FT /db_xref="InterPro:IPR010091" FT /db_xref="InterPro:IPR036291" FT /db_xref="UniProtKB/TrEMBL:G3XCL0" FT /protein_id="AAK01463.1" FT /translation="MSDVRSVVVAGSRFGQFYAAGVAADPRFVLRGILGQGSRRSRALA FT ERLGVETWCEVEALPDDVRLACVAVGGAARGEQGPALAEALMARGIDVLIEHPLLPREW FT QDLLRSAERLGRRCLLNTFYPQLPAVARFIELGRQLHRRRGIRHLDAACGVQVGFATLD FT ILAALLEGVGPWSLESPSNDLSAMRGLSLVLAEVPLSLLVLNELAAADDGRMTLLQRVS FT LTTDRGTLSLLSPHGPLLWTPAVAVPAEDDDGLFALFDEIAGEPLPSAQLWYAEPCSWA FT QVHQRLWPAAAAEALALLADGDEVRRRNQRSLEVAALWQRIGERLGFPEAPPASLAPAS FT LEQVLEQAS" FT CDS 11590..13302 FT /codon_start=1 FT /transl_table=11 FT /gene="pchH" FT /product="ABC transporter" FT /db_xref="GOA:G3XCL8" FT /db_xref="InterPro:IPR003439" FT /db_xref="InterPro:IPR003593" FT /db_xref="InterPro:IPR011527" FT /db_xref="InterPro:IPR017871" FT /db_xref="InterPro:IPR027417" FT /db_xref="InterPro:IPR036640" FT /db_xref="InterPro:IPR039421" FT /db_xref="UniProtKB/TrEMBL:G3XCL8" FT /protein_id="AAK01464.1" FT /translation="MTPVLWRLLRTYRWRLAAAMGLQALAGLCSLLPWMLLAWLAEPLA FT RGQAQPALLALVLLAVLAWLGCQALAAHLAHRVDADLCNDLRLRLLAHLQRLPLDWFGR FT QGPDGVARLVEQDVRALHQLIAHAPNDLSNLLVVPLVALLWLAWLHPWLLLFCLLPLVL FT AAAGFLLLRSARYRDLVLRRNAALERLSADYGEFAHNLLLARQYPGAGIQQGAEASAAA FT FGEAFGAWVKRVGHLAALVYVQLSTPWLLAWVLLGALALDALGVPLALGQACAFLLLLR FT ALAAPVQALGHGGDALLGARAAAERLQQVFDQAPLAEGRSTREPVDGAVALHGLGHAYE FT GVEVLADIDLELEDGSLVALVGPSGSGKSTLLHLLARYMDAQRGELEVGGLALKDMPDA FT VRHRHIALVGQQAAALEISLADNIALFRPDADLQEIRQAARDACLDERIMALPRGYDSV FT PGRDLQLSGGELQRLALARALLSPASLLLLDEPTSALDPQTARQVLRNLRERGGGRTRV FT IVAHRLAEVSDADLILVLVAGRLVERGEHAALLAADGAYARLWREQNGAEVAA" FT CDS 13299..15023 FT /codon_start=1 FT /transl_table=11 FT /gene="pchI" FT /product="ABC transporter" FT /db_xref="GOA:Q9AQH1" FT /db_xref="InterPro:IPR003439" FT /db_xref="InterPro:IPR003593" FT /db_xref="InterPro:IPR011527" FT /db_xref="InterPro:IPR017871" FT /db_xref="InterPro:IPR027417" FT /db_xref="InterPro:IPR036640" FT /db_xref="UniProtKB/TrEMBL:Q9AQH1" FT /protein_id="AAK01462.1" FT /translation="MTLFERMRALPEDCRAALRRASAWAVLAALLDAACGVLLVPLVEA FT WFAEGALPWRWVAALLGLSLAQALLQYLALRRGFAAGGSLAAGLVRSLVARLPRLAPPA FT LRRVAPAEGLLRGPVMQAMGIPAHLLGPLIAALVTPLGVILGLFLIDPSIALGLLLAGA FT FLAALLRWSGRRNLAAEDARLAAERDAARQLQAFAERQPLLRAAQRESVARQGLEEALR FT SLHRSTLDLLRRSLPSGLGFALAVQAAFAFALLGGAWAVERQWLDGARLVAVLVLLVRF FT IEPLAQLTHLDQALRGAWQALDTLLRVFALAPLRSPEPGERPHDASLAAEAVELRLEDG FT RALLEDISLRLEPGSLNVLVGPSGAGKSSLLALLGRLYDVDAGRVLLGGVDIRRLSETT FT LAASRNLVFQDNGLFRGSVAWNLRMARADADLEALREAARAVGLLEEIEAWPQGWDSDV FT GPGGALLSGGQRQRLCLARGLLSTAPLLLLDEPTASLDAASEAQVLRSLLGLRGRRTLL FT VLTHRPALARQADQVLLLEEGRLRLSGLHADLLVRDDWYAGFVGLAGEESSATVVDR" XX SQ Sequence 15023 BP; 1842 A; 5432 C; 5443 G; 2306 T; 0 other; agatctacgg caccgacaag ccgttgcgct acaccatcgt ccagctcggc gtcgaagccc 60 tggacagccg cctcggctgg ctgcccgagc aactgatacg ccgccccggc ggcgatccgc 120 ggatcatgag ctgcccggcg ccgcgggcga tgcaggcgtt ggcctcgcag atcgccacct 180 gccagatgct cggtccgacc cgcgatctct acctcggcgg caaggccctg gagttggccg 240 cgctcagcgc acagttcctt tccggcgagg ggcgccccgt cgaggagccg cgcatcacct 300 gctcggaggt cgagcgcatc cacgccgccc gcgacctgct ggtcggcgcc ttgcaggagc 360 cgccgtcgct ggacacgctg gccagccgcg tgggcatgaa cccgcgcaag ctgactgccg 420 gctttcgcaa ggtgttcggc gccagcgtat tcggctacct gcaggaatac cgcctgcgcg 480 aggcgcaccg gatgctctgc gacgaagagg cgaatgtctc cacggtggcc taccgggtgg 540 gctacagccc ggcgcatttc tccatcgctt tccgcaagcg ctacggcatc tcccccagcg 600 agatccgctg agtctccgcg acgacccccg acccggccac gggaggggcg tcgccgctgc 660 gggatgacgc tgcatctaac gaaacagtcc ggctgtctaa agcattgccg gccaggcctc 720 ccaggcaagt gagataaggt cgcatttgat aatcgttgcc aggaactggc aaccgacctc 780 agatgcttgc cctagggagc ccccatggat ctgccccccg attcccgtac cgccctgcgc 840 gactggctga ccgagcagct cgccgacctg ctcggcgaac cgcttgctga cgtgcgcgcc 900 ctggcggacg acgacgacct gctgggctgc ggcctcgact cgatccgcct gatgtacctg 960 caggaacgcc tgcgcgcgcg tggctcgacg ctggacttcg cccagttggc gcagcgcccc 1020 tgcctggggg cctggctcga cctgctggcc tgcgcggacc ggctgtccgc cccggcaacg 1080 gtcgcgctgc cgacggcgca ggatcgcgat cagccgttcg agctgtcttc cgtgcagcag 1140 gcctactggc tgggacgtgg cgccggcgag gtgctgggca acgtcagctg ccatgccttt 1200 ctggaattcc gcacgcggga tgtcgacccg cagcgcctgg ccgcggcggc ggagtgcgtg 1260 cgtcaacgcc acccgatgtt gcgggcgcgc ttcctcgacg gtcgccagca gatccttccg 1320 acgccgccgc tgtcctgctt cgacctgcag gactggcgca ccttacaggt ggacgaggcc 1380 gagcgcgact ggcaggcgct gcgcgactgg cgcgcccatg aatgcctggc ggtggagcgc 1440 ggccaggtgt tcctgctcgg gctggtgcgc atgccgggcg gcgaggatcg cctctggctg 1500 agtctcgacc tgcttgccgc cgatgtcgaa agcctgcgcc tgctgctggc cgaactgggc 1560 gttgcctacc tggcgccgga gcgcctggcg gagccgccgg cgctgcattt cgccgactac 1620 ctggcgcacc gtgcggcgca acgcgccgag gccgcggcgc gggcccgcga ctactggctg 1680 gaacgcctgc cgcgcttgcc ggacgcgccg gccctgccgt tggcctgcgc gccggaaagc 1740 atccgccagc cgcgcacccg gcgcctggca ttccagcttt ccgccggcga gagccggcgc 1800 ctggagcgtc ttgccgcgca gcatggcgtg accttgtcca gcgtgttcgg ctgcgccttc 1860 gcgctggtcc tggcgcgctg gagcgaaagc gcggaatttc tcctcaacgt gccgttgttc 1920 gatcggcatg ccgacgaccc gcgtatcggc gaggtgatcg ccgacttcac caccctgttg 1980 ctgctggagt gccggatgca ggccggggtg tccttcgccg aggcggtgaa gagcttccag 2040 cgcaacctcc acggagccat cgaccacgcc gcattccccg ccctggaggt gctccgcgag 2100 gcgcgccggc agggccagcc acgctcggcg ccggtggtgt tcgccagcaa cctgggcgag 2160 gagggcttcg tcccggcggc cttccgcgac gctttcggcg atctccacga catgctctcg 2220 cagaccccgc aggtctggct cgaccaccag ctctaccggg tgggcgacgg tatcctgctg 2280 gcctgggata gcgtcgtcgg cctgttcccc gaaggtctgc cggaaaccat gttcgaagcc 2340 tacgtggggc tgctccagcg tctctgcgac agcgcctggg ggcagcccgc cgatctgccg 2400 ttgccctggg cgcagcaggc gcgccgggcc ctgctcaacg gccagccggc atgcgccacg 2460 gcgcgcaccc tgcatcgcga cttcttcctt cgcgccgccg aggcgccgga tgccgacgcg 2520 ctgctctatc gcgaccaacg tgtcacccgc ggcgaactgg ccgagcgtgc gctgcgcatc 2580 gccggcggcc tgcgcgaagc cggggtgcgc cctggcgacg cggtcgaggt cagcctgccg 2640 cgcggaccgc agcaggtcgc ggcggtattc ggcgtgctcg ccgcaggcgc ctgctacgtg 2700 ccgttggaca tcgaccagcc gcccgcacgg cggcgcctga tcgaagaggc cgccggggta 2760 tgcctggcga tcaccgagga ggacgatccg caggccttgc cgccgcgcct ggatgtccag 2820 cgcctgctgc gcggcccggc gctggccgcc cccgtgccgc tggcgccgca ggcgagtgcc 2880 tatgtgatct acacctcggg ctccaccggg gtgcccaagg gcgtcgaggt cagccacgcg 2940 gcggcgatca ataccatcga cgcgctgctc gacctgctgc gggtgaacgc atcggatcgc 3000 ttgctggcgg tctccgcgct ggacttcgat ctgtcggtct tcgacctgtt cggcggcctc 3060 ggcgccggtg ccagcctggt cctgccggcc caggaacagg cgcgcgatgc cgctgcctgg 3120 gcggaggcta tccagcggca tgcggtgagc ctgtggaact cggcgccggc cttgctggag 3180 atggccctca gcctgccggc gagccaggcc gactatcgca gtctgcgggc ggtgctgctg 3240 tccggcgact gggtggccct ggacctgccc ggccgcctgc gcccacgttg tgccgaaggc 3300 tgccgcctgc atgtgctggg tggcgctacc gaagcgggca tctggtcgaa cctgcagagc 3360 gtcgatacgg tgccgccgca ctggcgttcg attccctacg gccggccatt gccgggacag 3420 gcctaccggg tggtcgacac ccacgggcgc gacgtgccgg acctggtggt cggcgagctg 3480 tggatcggcg gcgccagcct ggcccgcggc tatcgcaacg atcccgaact cagcgcccgg 3540 cgtttcgtcc acgatgccca gggccgctgg tatcgcaccg gcgatcgcgg tcgctactgg 3600 ggcgacggta ccctggaatt cctcggtcgg gtcgaccagc aggtgaaagt gcgcggccag 3660 cgcatcgagt tgggcgaggt ggaggccgcg ctgtgcgccc aggctggcgt ggagagcgcc 3720 tgcgcggcgg tgctcggcgg tggcgtggcg agcctcggcg cggtgctggt accgcgcctg 3780 gcgccacggg ccgaaggctc catggatcta ccggccgcac agcccttcgc cggcctggca 3840 gaggccgagg cggtactcac ccgggaaatc ctcggcgcgc tgctggaggc gccgctggag 3900 ctagacgacg gtttgcgccg gcgctggctg gactggctag cggactccgc cgccagcgcg 3960 ctgccgtcgc tcgacgaggc gttgcgccgg ctcggctggc aggccgcggg gctgaccgcg 4020 atgggcaacg ctctgcgcgg cctgctcgcc ggcgaacagg cgccggccgc gctgctcctc 4080 gatccctggc tggcgccgca ggcggtggcc gcgcgcctgc cggacggccg cgaggccctg 4140 gcgcgcctgc tcgaagcgct gccgacgccg gctgccggcg aacgcctgcg ggtggcggtg 4200 ctggataccc gcgccgggct ctggctcgac cagggcatgg cctcgctgtt gcgcccaggg 4260 ctggaactga ccctcttcga acgcagccgc gtcctcctcg acgccgccgc cacccgcttg 4320 ccggaacgga tcgtggtgca ggcgctggac gacggcctgc tacctgccga gcacctcggt 4380 cgctacgacc gggtgatcag cttcgccgcg ctgcacgcct acgaggccag ccgcgaaggc 4440 ctggcgctgg cggcggcgct gctgcgcccg cagggccgcc tgttgctggt ggacctgcta 4500 tgcgagtcgc cactggcgct gctcggtgcg gccttgctcg acgaccggcc gctgcgcctg 4560 gcggagctgc cgagcctgtt ggccgatctc gccgctgcgg gactggcgcc gcgttgcctg 4620 tggcgcagcg agcggatcgc cctggtcgag gcgctggcac cgggactcgg gctcgacgcc 4680 gccgcgctcc aggccggcct ggagcaacgc ctgccccagg cgatgcggcc cgaacgcctg 4740 tggtgcctgc caagcctgcc gttgaacggc aatggcaagg tcgatcgtcg ccgcctggcc 4800 gagagcatga cccgcgcact cggcgagtgt cgtcacgagc cctcggcgga ggagccgctg 4860 gaagcccatg agcaagcgct ggccgagtgc tgggaagcgg ttctcaaacg cccggtgcgt 4920 cgtcgcgagg cgagcttctt cagcctcggc ggcgacagcc tgctggcgac ccgcctgctg 4980 gccggcatac gtgagcgttt cggcgtacgc ctgggcatgg ccgacttcta tcgccagccg 5040 accctggccg gtcttgcccg ccacttgcag gtgcagaccg tcgaaatcga ggaaacccaa 5100 ctggaagagg gcgtgctatg agcctcggcg aactgctgga aacctgccgc agccggcgca 5160 tcgaactctg gagcgaggcg ggccgcctgc gctatcgcgc cccccagggt gccctcgacg 5220 ccggcctcgc cgagcgcctg cgggccgagc gcgaggccct gctggaacac ctggaaggcg 5280 gccctggctg gcgcgccgaa cccgacatgg cccaccagcg cttcccgctg accccggtgc 5340 aggccgccta cgtgctgggc cgccaggcgg ccttcgacta cggcggtaac gcctgccagc 5400 tgtacgccga gtacgactgg ccggccgaca ccgatccggc gcgcctggag gcggcctgga 5460 acgccatggt cgagcgccac ccgatgctgc gcgcggtgat cgaggacaac gcctggcagc 5520 gcgtgctgcc cgaggtgccc tggcagcggc tgaccgtgca tgcctgcgcg gggctcgacg 5580 aggccgcttt ccaggcgcac ctggagcggg tccgcgaacg cctcgaccac gcctgcgcgg 5640 cgctcgacca gtggccggtc ctgcgccccg agctgagtat cggccgggat gcctgcgtac 5700 tgcactgctc ggtggatttc accctggtcg actacgccag cctgcaattg ctgcttggcg 5760 aatggcgccg ccgctatctc gatccgcaat ggacggcgga accgctggag gcgaccttcc 5820 gcgactatgt cggcgtcgag cagcgccgac gccagtcgcc agcctggcag cgcgaccgcg 5880 actggtggct ggcgcgtctc gacgcgctac cggggcgtcc cgacctgccg ctgcgggtgc 5940 agccggacac ccggtccacg cgcttccggc acttccacgc gcgcctcgac gaggccgcct 6000 ggcaggcgct cggcgcgcgc gccggcgaac acggcctgag cgctgccggc gtggccttgg 6060 cggccttcgc cgagaccatc ggtcgctgga gccaggcacc ggcgttctgt ctcaacctga 6120 cggtactcaa ccggccgccg ctgcatccgc agctggcgca ggtgctcggt gacttcaccg 6180 cgctcagcct gctggcagtg gacagccgcc acggcgacag tttcgtcgag cgtgcccgac 6240 gcatcggcga gcagatgttc gacgacctcg accacccgac cttcagcggc gtcgacctgc 6300 tgcgcgaact ggcgcgccgg cgtggtcgcg gcgccgatct gatgccggtg gtgttcacca 6360 gtggcatcgg cagcgtgcag cgcctgctcg gcgatggcga ggcgccgcgc gcgccacgct 6420 acatgatcag ccagaccccg caggtctggc tggactgcca ggtcaccgac cagttcggcg 6480 gcctggagat cggctgggac gtacgcctcg ggttgttccc cgagggccag gcggaagcca 6540 tgttcgacga cttcgtcggg ctgctccggc gcctggcgca gagcccgcgc gcctggaccg 6600 acggcgatgc cacggaaccc gtcgaggcgc cgccgcaggc gttgcccggt agtgcccgga 6660 gcatcgccgc cggtttcgcc gagcgtgccc tgctgacccc cgacgccacg gcgatccacg 6720 atgccgccgg cagctacagc taccgccagg tcgcccagca cgccagcgcc ctgcgccgcg 6780 tcctggaagc gcacggcgcg ggccgtggcc ggcgggtcgc ggtgatgctg ccgaaaagcg 6840 ccgcgcaatt ggtcgcggtg atcggcatcc tccaggccgg cgccgcctat gtgccggtgg 6900 acatccgcca gcctccgctg cggcgccagg cgatcctcgc cagcgccgaa gtggtcgcgc 6960 tggtctgcct ggaaagcgat gtcccggacg tcggctgcgc ctgcgtggcc atcgaccggc 7020 tggccgccga cagcgcctgg ccgccaccgc ccgcggcgga ggtggcggcg gacgacctcg 7080 cctacgtgat ctacacctcc ggctccaccg gcacgccaaa gggcgtgatg ctcagccatg 7140 cggcggtgag caacacgctg ctcgacatca accagcgcta cggcgtcgac gccaacgacc 7200 gcgtcctcgg cctcgccgag ctgagcttcg acctctcggt ctacgacttc ttcggcgcca 7260 ccgcggcggg ggcccaggtg gtcctcccgg acccggcgcg cggcagcgat ccatcgcact 7320 gggcggaact gctggaacgc cacgccatca ccctgtggaa ctcggtgccg gcccaaggcc 7380 agatgctcat cgattacctg gagagcgagc cgcaacgtca cctgccggga ccgcgctgcg 7440 tgctctggtc cggtgactgg attccggtca gcctgccgac ccgctggtgg cggcgctggc 7500 cggacagcgc cgctgttcag cctgggcggc gcaccgaggc ggcgatctgg tcgatcgagc 7560 agccgatccg cccgcagcac accgagctgg ccagcatccc ttatggccgt gccctgcgcg 7620 ggcagagcgt ggaagtcctg gatgcccgcg ggcggcgctg cccgccgggc gtgcgcggcg 7680 agatccatat cggcggggtg ggcctggcgc tcggctacgc cggcgatccg cagcgcaccg 7740 ccgaacgctt cgtccgtcac cccgatggcc gtcgcctgta tcgcaccggc gacctcggcc 7800 gctacctggc cgacggcagc atcgagttcc tcggccgcga ggacgaccag gtgaagattc 7860 gcggccaccg catcgaactg gccgaactgg acgccgcgct gtgcgctcat ccgcaggtca 7920 acctggcggc caccgtggtg ctcggcgaga cccacgagcg cagcctggcc agcttcgtca 7980 ccctgcatgc gccggtggag gctggcgagg atccgcgtac ggcgctcgac gcggtgcgcc 8040 agcgggcggc ccaggccttg cgccgcgact ggggcagcga ggagggcatc gccgcggcgg 8100 tggccgcact cgaccgtgcc tgcctcgcct cgttggccgc ctggctggcc ggcagcggtc 8160 tgttcgccag tgcgacgccg ctggacttag ccaccctgtg ccagcgcctg ggtatcgccg 8220 aggcgcgcca gcgcctgctg cgccactggt tgcgccaact ggaggagggc ggctacctgc 8280 gcgccgaggg cgagggctgg ctgggctgcg ccgagcgtcc cgcgcagagt ccggaggacg 8340 cctggacggc gttcgccggc tgcgcgccgg cggcgctctg gccggccgag ctggtcgcct 8400 acctgcgtga cagcgcgcaa tccctcggcg agcaactggc cgggcggatc agcccggcgg 8460 cgctgatgtt cccgcagggc tcggcgcgca tcgccgaggc catgtacagc cagggcctgc 8520 atgcccaggc gctgcacgag gccatggccg aggccatcgc cgccatcgtc gagcgccagc 8580 cgcaacggcg ctggcgcctg ctggagcttg gcgccggcac cgccgccgcc agccgcacgg 8640 tgatcgcccg gttggcgccg ctggtgcagc gaggggcgga ggtggactac ctgttcaccg 8700 acgtttccag ctacttcctc gccgccgccc gcgagcgctt cgccgaccag ccgtgggtac 8760 gcttcggccg cttcgacatg aacggcgatc ttctcgacca gggcgtggcg ccgcactcgg 8820 tggatatcct gctcagctcc ggggccttga acaacgcgct ggacaccccg gcgctgctgg 8880 ccggcctgcg cgagttgctg agcgccgacg cctggctggt gatccaggaa ctgacgcgcg 8940 agcacaacga gatcagcgtc agccagagcc tgatgatgga aaacccgcgc gacctccgcg 9000 acgagcgccg ccaactgttc gtccacaccg ggcaatggct ggagtggctg gcggcacagg 9060 gtggcgacct ggcttgtggg gtggtgccgc cgggcagcgc tctcgacctg cttggctacg 9120 atgtcctgct ggctcgctgc aagaccgacc gcgcccgcct ggagccggcc gagctgctgg 9180 ccttcgtcga agcgcgggtg ccgcgctaca tgctcccggc gcagttgcgc gtgctcgaac 9240 gcctgccggt caccggcaac ggcaagatcg accgcaaggc cctgaccggc tttgcccgcc 9300 agccccaggc ggaccttcgg catggcgtcg cgcaggcacc ggccgacgaa ctggagaatg 9360 cgctgctggc actctggcgg gaggtgctgg acaacccgtc gctgggcgtc gagcaagact 9420 tcttcggggc cggcggcgac tcgctgttga tcgcccagtt gatcgcccgt ttgcgcgaac 9480 gactggaaag cgcccgtcgg catccgttcg atcgcctgct acgctgggcg ctcagccagc 9540 cgacgccgcg cggcctggcc gaacgcctgc gcagcgcgcc ggaagagggc cgtgggccag 9600 ccctggccgc ggcgcgcggc gtcgccccgg cgccggccgg catgtcgcgc gcaccgctcg 9660 ccgagggcgc ggtggcgctc gacccgctgg tgcgcctggt gcccggcgag ggcgtgccgc 9720 gggtgctggt ccacgaaggc ctcggcacgc tactgccgta ccgcccgctg cttcgcgccc 9780 tgggtgaggg gcggccgttg ctggggctgg ccgtgcatga cagcgacgcc tacctggcga 9840 tccccgccga gcatctcaac gcctgcctcg gccgccgcta cgccgaggcg ctccatcgcg 9900 ccgggctacg cgaggtcgac ctgctcggct actgctccgg cgggctggtc gccctggaga 9960 ccgccaagtc cctggtccag cgcggggtgc gcgtgcgcca actggatatc gtctccagct 10020 accggattcc ctaccgggtg gacgacgagc gcctgctgtt gttcagcttc gccgcgaccc 10080 tcggcctgga taccgcggcg ctcggcttcc ccgcgccgga acgtctcggc caggcggtgc 10140 aggcggcgct cgcgcagaca ccggagcgcc tggtcgccga ggcgctggcg gggctgccgg 10200 gcctggccga tctcgtcgcc ctgcgcggcc gcgtgctaca ggcggccagc ggtagcgccg 10260 acgccgtcag cgtcgaacgc gacaccctct accggctgtt ctgtcactcg gtgcgtgcca 10320 gccaggccga ggcgccggag ccctacgtcg gcgcgctgcg gctgttcgtg ccggacgccg 10380 gcaacccatt ggtgccgcgc tacgccgagg ctctggagac ccaatggcgg gccgccgcgc 10440 ttggcgcgtg cggcatccac gaggtgcccg gcgggcactt cgactgcctg ggcgaagccc 10500 tggcgcaatc cttgtcgaaa cccatgccag aggaggcgag ccgatgagcg acgtccgttc 10560 cgtggtggtc gccggttccc ggttcggcca gttctatgcc gccggcgtcg ccgccgatcc 10620 gcgcttcgtc ctgcgcggca tccttggcca gggcagccgg cgttcgcggg cgttggccga 10680 acgcctcggg gtggagacct ggtgcgaggt cgaggcgttg cccgacgatg tccgcctggc 10740 ctgcgtcgcg gtcggcggcg cggcacgcgg cgagcagggc ccggcgctgg ccgaggcgct 10800 gatggcgcgt ggcatcgacg tgctgatcga gcatccgttg ctgccgcgcg aatggcagga 10860 cctgctgcgc agcgccgagc gcctgggccg gcgctgcctg ctcaacacct tctatccgca 10920 gttgccggcg gtggcgcgtt tcatcgagct gggccgccag ttgcatcgcc ggcgcggcat 10980 ccgccacctg gacgcggcct gcggggtgca ggtcggtttc gccaccctgg acatcctcgc 11040 cgcgttgctg gagggcgttg gcccctggtc gctggagtcg ccctcgaacg acctgtcggc 11100 gatgcgcggg ctgtccctgg tgttggcgga agtgccattg agcctgctcg tgctcaacga 11160 actggcggcc gccgacgacg ggcgcatgac cttgttgcag cgcgtcagcc tgaccaccga 11220 tcgcggcacg ctgagcctgc tcagccccca tggcccgttg ttgtggacgc ctgcggtggc 11280 ggtaccggca gaggatgacg acggcctgtt cgcgctgttc gacgagatag ccggcgaacc 11340 gctgcccagc gcccagctct ggtatgccga accgtgcagc tgggcccagg tgcaccagcg 11400 cctgtggccg gcggcggcgg ccgaggcgct ggcgctgctc gccgacggcg acgaggtgcg 11460 ccggcgcaac cagcgcagcc tggaggtcgc cgccctgtgg cagcggatcg gcgagcgcct 11520 tggcttcccc gaggcgccgc cggcgtcgct ggcgccggcg agcctggaac aggtgctgga 11580 gcaagcctcg tgaccccggt gctgtggcgc ctgctgcgca cctatcgctg gcggctggcg 11640 gcggccatgg ggttgcaggc cctggccggg ctctgctcgc tgttgccctg gatgcttctc 11700 gcctggctcg ccgagccgct ggcgcgcggc caggcgcagc cggccctgct ggccctggtg 11760 ctgctggcgg tgctggcctg gctgggctgc caggcgctgg ccgcgcacct ggcccaccgg 11820 gtcgacgcgg acctctgcaa cgacctgcgc ctgcgcctgc tggcgcacct gcaacggctg 11880 ccgctggact ggttcggtcg ccagggcccg gacggcgtgg cgcgcctcgt ggagcaggac 11940 gtgcgggccc tgcaccaact gatcgcgcac gctcccaacg atctcagcaa cctgttggtg 12000 gtgccgctcg tcgcgttgct ctggctggcc tggctgcacc cctggctgct gctgttctgc 12060 ctgctgccgc tggtgctggc cgccgccggc ttcctgctgc tgcgctcggc gcgctaccgc 12120 gacctggtgc tgcggcgcaa cgccgcgctg gaaaggctct cggcggacta tggcgaattc 12180 gcccacaacc tgctgctggc ccgacagtac cccggcgccg gcatacaaca gggcgccgag 12240 gcgtcggcgg cggccttcgg cgaagcgttc ggcgcctggg tgaagcgggt cggccacctc 12300 gccgcgctgg tctacgtgca gttgtcgacg ccctggctgc tggcctgggt cctgctcggc 12360 gcgctggccc tggatgccct cggcgtgccg ctggcgctcg gccaggcctg tgccttcctg 12420 ctcctgctgc gggccttggc tgccccggtg caggcgctcg gccacggcgg cgacgcgctg 12480 ctgggcgcgc gcgccgccgc cgagcgcctg cagcaggtgt tcgaccaggc gccgctggcc 12540 gagggccgct cgacccgcga gccggtcgat ggcgcggtgg cgctgcacgg cctgggccat 12600 gcctatgaag gcgtggaggt cctggccgat atcgatctgg agctggagga tggcagcctg 12660 gtggccctgg tcggtccctc gggctccggc aagagcaccc tgctgcacct gctggcgcgc 12720 tacatggacg cgcagcgcgg cgaactggag gttggcggcc tggcactgaa ggacatgcct 12780 gatgccgtgc gccatcggca tatcgcgctg gtcggccagc aggcggcggc gctggagata 12840 tccctggccg acaacattgc cctgttccgc cccgatgccg atctccagga gattcgccag 12900 gcggcccgtg acgcctgcct cgacgagcgc atcatggccc tgccgcgtgg ctacgacagc 12960 gtgccgggac gcgacctgca actgtccggc ggcgaactgc aacgactggc cctggcccgt 13020 gcgctgctat cgccggcgag cctgttgctg ctcgacgagc caacctcggc gctggatccg 13080 cagaccgccc ggcaggtcct gcgcaacctg cgcgaacgcg gcggtggccg gacccgggtg 13140 atcgtcgccc atcgtctggc cgaagtcagc gatgccgacc tgatcctggt gctggtcgct 13200 ggccgtctgg tcgaacgcgg cgagcacgcg gcgctgttgg cggcggacgg cgcctatgcg 13260 cgcttgtggc gtgaacagaa cggcgcggag gtggcggcat gaccctgttc gaacgaatgc 13320 gtgcgctgcc cgaagactgc cgtgccgcgt tgcgccgggc gagcgcctgg gcggtcctgg 13380 cggcgctgct ggacgccgct tgcggcgtat tgctggtgcc gttggtcgag gcctggttcg 13440 ccgaaggcgc gttgccctgg cgctgggtcg ccgcgttgct cggcttgagc ctggcgcagg 13500 cgctgttgca gtacctggcc ctgcgtcgcg gtttcgccgc cggcggctcg ctggcggctg 13560 gactggtgcg cagcctggtg gcgcgcttgc cgcgcctggc gccgccggcg ctgcgccggg 13620 tcgcgccggc cgaaggcctg ctgcgcggcc cggtgatgca ggcgatgggc attccggcgc 13680 acctgctggg gccgctgatc gccgcgttgg tgacgccgct cggggtgatc ctcgggctgt 13740 tcctgatcga cccgtccatc gccctcggcc tgctccttgc tggtgccttc ctcgccgcgc 13800 tgttgcgctg gagcgggcgg cgcaatctgg cggcggagga tgcccggctg gccgccgagc 13860 gcgacgccgc acggcagttg caggcgttcg ccgaacgcca gccactgctg cgcgcggcgc 13920 agcgcgaaag cgtcgcccgc caggggctgg aagaggcctt gcgcagtctc caccgcagca 13980 ccctggatct gttgcggcgc agcctgccca gcggcctcgg cttcgccctg gcggtgcagg 14040 cggcgttcgc cttcgccctg ctcggcggcg cctgggcggt ggagcggcaa tggctggacg 14100 gcgctcggct ggtggccgtg ctggtgctgc tggtgcgctt catcgagccg ctggcccagc 14160 tcacccatct cgaccaggcg ttgcgcggcg cctggcaggc gctggatacc ctgctgcggg 14220 ttttcgccct ggctccgctg cgcagccccg agccgggcga gcggccgcac gacgccagcc 14280 tggcggccga ggccgtggaa ttgcgcctgg aagatggccg cgccttgctc gaggacattt 14340 ccctgaggct ggagccgggt tcgctgaacg tcctcgtcgg accctccggg gccggcaaga 14400 gcagcctgct ggcgctgctc gggcggctct acgacgtcga tgccgggcgt gtcctgctgg 14460 gtggcgtgga tatccgccgg ttgagcgaaa cgaccctcgc cgccagtcgt aacctggtgt 14520 tccaggacaa cggcctgttc cgcggcagcg ttgcctggaa cctgcgcatg gcgcgagcgg 14580 acgccgatct cgaagcgctg cgcgaggcgg cgcgggcggt tggcctgctg gaagagatcg 14640 aggcctggcc gcagggctgg gacagcgacg tcggtcccgg cggcgcgctg ctgtccggcg 14700 gccagcggca acgcctgtgc ctggctcgcg ggctgctctc gacggcgccg ttgctgctgc 14760 tcgacgagcc caccgccagc ctcgacgccg ccagcgaggc gcaggtgctg cgcagcctgc 14820 tcgggttgcg cggccggcgc accctgctgg tattgaccca ccgcccggcg ctggcgcgtc 14880 aggccgacca ggtactgctg ctggaggagg ggcgcctgcg cctcagcgga cttcacgccg 14940 atctgctcgt ccgggacgac tggtatgccg gtttcgtcgg gctggcgggc gaggaaagtt 15000 ccgcgacggt cgtggatcga tag 15023 //