Qualifier
germline
Definition the sequence presented in the entry has not undergone somatic rearrangement as part of an adaptive immune response; it is the unrearranged sequence that was inherited from the parental germline
Value Format
none
Example /germline
Comment /germline should not be used to indicate that the source of the sequence is a gamete or germ cell; /germline and /rearranged cannot be used in the same source feature; /germline and /rearranged should only be used for molecules that can undergo somatic rearrangements as part of an adaptive immune response; these are the T-cell receptor (TCR) and immunoglobulin loci in the jawed vertebrates, and the unrelated variable lymphocyte receptor (VLR) locus in the jawless fish (lampreys and hagfish); /germline and /rearranged should not be used outside of the Craniata (taxid=89593)