{"EMPIAR-14096":{"imagesets":[{"segmentations":[],"name":"THO-UAP56 full-size motion-corrected micrographs (dataset 1)","directory":"data/human_THO_UAP56_2019/november_fullsize_micrographs","category":"micrographs - single frame","header_format":"MRC","data_format":"MRC","num_images_or_tilt_series":6856,"frames_per_image":1,"frame_range_min":null,"frame_range_max":null,"voxel_type":"16 BIT FLOAT","pixel_width":0.86,"pixel_height":0.86,"micrographs_file_pattern":"","picked_particles_file_pattern":"","picked_particles_directory":"","details":"Recombinant human THO (THOC1, THOC2 residues 1-1203, THOC3, THOC5, THOC6, THOC7) with full-length UAP56, GraFix crosslinked. Acquired on a 300 kV Titan Krios G3i with a Gatan K3 detector at nominal 0.86 A/pixel (0.43 A/pixel super-resolution movie mode); 33 frames, 3.8 s exposure, total dose 50 e-/A^2, nominal defocus -0.4 to -3.7 micrometres. Deposited images are single-frame Warp motion-corrected MRC micrographs, not the original movies. MRC mode 12 is 16-bit float. No particle STAR files or particle stacks are included. Session 18-20 November 2019. Only the 6,856 full-size micrographs in the published processing subset are included.","image_width":"5760","image_height":"4092"},{"segmentations":[],"name":"THO-UAP56 full-size motion-corrected micrographs (dataset 2)","directory":"data/human_THO_UAP56_2019/december_fullsize_micrographs","category":"micrographs - single frame","header_format":"MRC","data_format":"MRC","num_images_or_tilt_series":18821,"frames_per_image":1,"frame_range_min":null,"frame_range_max":null,"voxel_type":"16 BIT FLOAT","pixel_width":0.86,"pixel_height":0.86,"micrographs_file_pattern":"","picked_particles_file_pattern":"","picked_particles_directory":"","details":"Recombinant human THO (THOC1, THOC2 residues 1-1203, THOC3, THOC5, THOC6, THOC7) with full-length UAP56, GraFix crosslinked. Acquired on a 300 kV Titan Krios G3i with a Gatan K3 detector at nominal 0.86 A/pixel (0.43 A/pixel super-resolution movie mode); 33 frames, 3.8 s exposure, total dose 50 e-/A^2, nominal defocus -0.4 to -3.7 micrometres. Deposited images are single-frame Warp motion-corrected MRC micrographs, not the original movies. MRC mode 12 is 16-bit float. No particle STAR files or particle stacks are included. Session 2-7 December 2019. Only the 18,821 full-size micrographs in the published processing subset are included.","image_width":"5760","image_height":"4092"}],"workflow_file":null,"grant_references":[],"version_history":[],"title":"Cryo-EM micrographs of recombinant human THO-UAP56 complex","principal_investigator":[{"author_orcid":"0000-0002-6020-9514","middle_name":null,"organization":"Research Institute of Molecular Pathology (IMP)","street":"Campus-Vienna-Biocenter 1","town_or_city":"Vienna","state_or_province":null,"post_or_zip":"1030","telephone":null,"fax":null,"first_name":"Clemens","last_name":"Plaschka","email":"clemens.plaschka [at] imp.ac.at","country":"Austria","entry":"EMPIAR-14096"}],"status":"REL","deposition_date":"2026-10-28","release_date":"2026-11-02","obsolete_date":null,"update_date":"2026-11-02","corresponding_author":{"author":{"author_orcid":"0000-0001-5975-5609","middle_name":"Kopano","organization":"Research Institute of Molecular Pathology (IMP)","street":"Campus-Vienna-Biocenter 1","town_or_city":"Vienna","state_or_province":null,"post_or_zip":"1030","first_name":"Matthias","last_name":"Vorländer","country":"Austria"}},"authors":[{"author":{"name":"Pühringer T","author_orcid":"0000-0001-9127-9120"}},{"author":{"name":"Hohmann U","author_orcid":"0000-0003-2124-1439"}},{"author":{"name":"Vorländer MK","author_orcid":"0000-0001-5975-5609"}},{"author":{"name":"Plaschka C","author_orcid":"0000-0002-6020-9514"}}],"cross_references":["EMD-14808","EMD-14809","EMD-11853","EMD-11857","EMD-11856","EMD-11854","EMD-11855"],"biostudies_references":[],"idr_references":[],"empiar_references":[],"citation":[{"authors":[{"name":"Pühringer T","author_orcid":"0000-0001-9127-9120"},{"name":"Hohmann U","author_orcid":"0000-0003-2124-1439"},{"name":"Fin L","author_orcid":null},{"name":"Pacheco-Fiallos B","author_orcid":"0000-0001-5398-5809"},{"name":"Schellhaas U","author_orcid":"0000-0002-9684-9839"},{"name":"Brennecke J","author_orcid":null},{"name":"Plaschka C","author_orcid":"0000-0002-6020-9514"}],"editors":[],"published":true,"j_or_nj_citation":true,"title":"Structure of the human core transcription-export complex reveals a hub for multivalent interactions","volume":"9","country":"United States","first_page":null,"last_page":null,"year":"2020","language":"English","doi":"10.7554/eLife.61503","pubmedid":"33191911","details":null,"book_chapter_title":null,"publisher":null,"publication_location":null,"journal":"eLife","journal_abbreviation":"eLife","issue":null,"preprint":false},{"authors":[{"name":"Pacheco-Fiallos B","author_orcid":"0000-0001-5398-5809"},{"name":"Vorländer MK","author_orcid":"0000-0001-5975-5609"},{"name":"Riabov-Bassat D","author_orcid":null},{"name":"Fin L","author_orcid":null},{"name":"O’Reilly FJ","author_orcid":null},{"name":"Ayala FI","author_orcid":null},{"name":"Schellhaas U","author_orcid":"0000-0002-9684-9839"},{"name":"Rappsilber J","author_orcid":null},{"name":"Plaschka C","author_orcid":"0000-0002-6020-9514"}],"editors":[],"published":true,"j_or_nj_citation":true,"title":"mRNA recognition and packaging by the human transcription-export complex","volume":"616","country":"United Kingdom","first_page":"828","last_page":"835","year":"2023","language":"English","doi":"10.1038/s41586-023-05904-0","pubmedid":"37020021","details":null,"book_chapter_title":null,"publisher":null,"publication_location":null,"journal":"Nature","journal_abbreviation":"Nature","issue":"7958","preprint":false}],"dataset_size":"1.1 TB","experiment_type":"EMDB","scale":"molecule","related_pdb_entries":["7znl","7apk"],"entry_doi":"10.6019/EMPIAR-14096"}}