{"EMPIAR-14002":{"imagesets":[{"segmentations":[],"name":"Human ILSAQR dataset 1 dose-weighted micrographs","directory":"data/ILSAQR_spliceosome/dataset_1/micrographs","category":"micrographs - single frame","header_format":"MRC","data_format":"MRC","num_images_or_tilt_series":26091,"frames_per_image":1,"frame_range_min":null,"frame_range_max":null,"voxel_type":"32 BIT FLOAT","pixel_width":0.951,"pixel_height":0.951,"micrographs_file_pattern":"","picked_particles_file_pattern":"","picked_particles_directory":"","details":"Processed dose-weighted single-frame micrographs generated from 40-frame EER movies acquired on a Titan Krios G4 with a Falcon 4i detector at 300 kV, Cs 2.7 mm, total exposure 40 e-/A^2 and nominal defocus -1.0 to -2.5 um.","image_width":"4096","image_height":"4096"},{"segmentations":[],"name":"Human ILSAQR dataset 2 dose-weighted micrographs","directory":"data/ILSAQR_spliceosome/dataset_2/micrographs","category":"micrographs - single frame","header_format":"MRC","data_format":"MRC","num_images_or_tilt_series":27327,"frames_per_image":1,"frame_range_min":null,"frame_range_max":null,"voxel_type":"32 BIT FLOAT","pixel_width":0.951,"pixel_height":0.951,"micrographs_file_pattern":"","picked_particles_file_pattern":"","picked_particles_directory":"","details":"Processed dose-weighted single-frame micrographs generated from 40-frame EER movies acquired on a Titan Krios G4 with a Falcon 4i detector at 300 kV, Cs 2.7 mm, total exposure 40 e-/A^2 and nominal defocus -1.0 to -2.5 um.  Supplementary RELION STAR files are included for EMD-54467 to EMD-54477 and use CryoSPARC particle counts; Map 8 is named TFIP11-GCFC2. Particle stacks are not deposited.","image_width":"4096","image_height":"4096"}],"workflow_file":null,"grant_references":[],"version_history":[],"title":"Single-particle cryo-EM dataset of the Human intron-lariat spliceosome–Aquarius (ILSAQR)","principal_investigator":[{"author_orcid":null,"middle_name":null,"organization":"Research Institute of Molecular Pathology (IMP)","street":"Campus-Vienna-Biocenter 1","town_or_city":"Vienna","state_or_province":null,"post_or_zip":"1030","telephone":null,"fax":null,"first_name":"Clemens","last_name":"Plaschka","email":"clemens.plaschka [at] imp.ac.at","country":"Austria","entry":"EMPIAR-14002"}],"status":"REL","deposition_date":"2026-09-21","release_date":"2026-11-09","obsolete_date":null,"update_date":"2026-11-09","corresponding_author":{"author":{"author_orcid":null,"middle_name":"Kopano","organization":"Research Institute of Molecular Pathology (IMP)","street":"Campus-Vienna-Biocenter 1","town_or_city":"Vienna","state_or_province":null,"post_or_zip":"1030","first_name":"Matthias","last_name":"Vorländer","country":"Austria"}},"authors":[{"author":{"name":"Vorländer MK","author_orcid":"0000-0001-5975-5609"}},{"author":{"name":"Boreikaite V","author_orcid":null}},{"author":{"name":"Plaschka C","author_orcid":"0000-0002-6020-9514"}}],"cross_references":["EMD-54469","EMD-54473","EMD-54472","EMD-54471","EMD-54468","EMD-54493","EMD-54477","EMD-54476","EMD-54474","EMD-54475"],"biostudies_references":[],"idr_references":[],"empiar_references":[],"citation":[{"authors":[{"name":"Boreikaite V","author_orcid":null},{"name":"Faraway R","author_orcid":null},{"name":"Vorländer MK","author_orcid":null},{"name":"Phillips AW","author_orcid":null},{"name":"Opitz L","author_orcid":null},{"name":"Wanke M","author_orcid":null},{"name":"Yakoub G","author_orcid":null},{"name":"Raffl G","author_orcid":null},{"name":"Fin L","author_orcid":null},{"name":"González-Prieto R","author_orcid":null},{"name":"Luijsterburg MS","author_orcid":null},{"name":"Ameres SL","author_orcid":null},{"name":"Plaschka C","author_orcid":null}],"editors":[],"published":false,"j_or_nj_citation":true,"title":"Mechanism of spliceosome termination","volume":null,"country":"United Kingdom","first_page":null,"last_page":null,"year":"2026","language":null,"doi":null,"pubmedid":null,"details":null,"book_chapter_title":null,"publisher":null,"publication_location":null,"journal":"Nature","journal_abbreviation":"","issue":null,"preprint":false}],"dataset_size":"3.3 TB","experiment_type":"EMDB","scale":"molecule","related_pdb_entries":["9s2e"],"entry_doi":"10.6019/EMPIAR-14002"}}