{"EMPIAR-13980":{"imagesets":[{"segmentations":[],"name":"Unaligned multi-frame movies","directory":"data","category":"micrographs - multiframe","header_format":"TIFF","data_format":"TIFF","num_images_or_tilt_series":4757,"frames_per_image":51,"frame_range_min":1,"frame_range_max":51,"voxel_type":"UNSIGNED BYTE","pixel_width":0.437,"pixel_height":0.437,"micrographs_file_pattern":"data/20oct19a*frames.tif","picked_particles_file_pattern":"","picked_particles_directory":"","details":"","image_width":"11520","image_height":"8184"}],"workflow_file":null,"grant_references":[],"version_history":[],"title":"Cryo-EM Structure of PRMT5/MEP50/pICln Complex","principal_investigator":[{"author_orcid":"0000-0002-1292-2411","middle_name":null,"organization":"The Pennsylvania State University","street":"201 Old Main","town_or_city":"University Park","state_or_province":"PA","post_or_zip":"16802","telephone":null,"fax":null,"first_name":"Wen","last_name":"Jiang","email":"wxj5136 [at] psu.edu","country":"United States","entry":"EMPIAR-13980"}],"status":"REL","deposition_date":"2026-09-20","release_date":"2026-10-05","obsolete_date":null,"update_date":"2026-10-05","corresponding_author":{"author":{"author_orcid":"0000-0002-1292-2411","middle_name":null,"organization":"The Pennsylvania State University","street":"201 Old Main","town_or_city":"University Park","state_or_province":"PA","post_or_zip":"16802","first_name":"Wen","last_name":"Jiang","country":"United States"}},"authors":[{"author":{"name":"Xu X","author_orcid":null}},{"author":{"name":"Li C","author_orcid":null}},{"author":{"name":"Jiang W","author_orcid":"0000-0002-1292-2411"}},{"author":{"name":"Hu CD","author_orcid":null}}],"cross_references":["EMD-73801","EMD-73799"],"biostudies_references":[],"idr_references":[],"empiar_references":[],"citation":[{"authors":[{"name":"Chi Z","author_orcid":null},{"name":"Xu X","author_orcid":null},{"name":"Shen Z","author_orcid":null},{"name":"Deng X","author_orcid":null},{"name":"Elzey BD","author_orcid":null},{"name":"Li C","author_orcid":null},{"name":"Jiang W","author_orcid":"0000-0002-1292-2411"},{"name":"Hu CD","author_orcid":null}],"editors":[],"published":true,"j_or_nj_citation":true,"title":"Cryo-EM structure-based discovery of etravirine as a specific inhibitor of PRMT5/pICln protein-protein interaction for prostate cancer treatment","volume":"41","country":"","first_page":null,"last_page":null,"year":"2026","language":"English","doi":"10.1080/14756366.2026.2727844","pubmedid":"42710907","details":"Microscope: Titan Krios G1 with Gatan Quantum GIF energy filter; Voltage: 300 kV; Cs: 2.7 mm; Camera: Gatan K3 in super-resolution mode; Pixel size: 0.437 Å; Dose:  60.5 e/Å^2 fractionated into 51 frames","book_chapter_title":null,"publisher":null,"publication_location":null,"journal":"Journal of enzyme inhibition and medicinal chemistry","journal_abbreviation":"J Enzyme Inhib Med Chem","issue":"1","preprint":false}],"dataset_size":"2.1 TB","experiment_type":"EMDB","scale":"molecule","related_pdb_entries":["9z4a","9z49"],"entry_doi":"10.6019/EMPIAR-13980"}}