{"EMPIAR-13947":{"imagesets":[{"segmentations":[],"name":"Unaligned multi-frame movies of integrin a4b7 bound to act1 fab","directory":"data/movies","category":"micrographs - multiframe","header_format":"TIFF","data_format":"TIFF","num_images_or_tilt_series":1510,"frames_per_image":100,"frame_range_min":null,"frame_range_max":null,"voxel_type":"UNSIGNED 16 BIT INTEGER","pixel_width":0.561,"pixel_height":0.561,"micrographs_file_pattern":"data/micrographs","picked_particles_file_pattern":"data/particles/particles.star","picked_particles_directory":"data/particles","details":"Unaligned uncorrected movies were recorded automatically using SerialEM on a K3 camera in super-resolution mode on a Glacios microscope operated at 200 kV (Cs=2.7). The total dose per micrograph is ~50 e/Å^2. A gain reference is provided in data/gain_ref. Images were dose-weighted and motion-corrected in MotionCor2 via the RELION GUI. Images were binned by 2 using Fourier cropping and the binned pixel size is 1.122. Particles were picked, extracted, and processed in cryoSPARC.","image_width":"5760","image_height":"4092"}],"workflow_file":null,"grant_references":[{"funding_body":"National Institutes of Health (NIH)","code":"R35GM147414","country":"United States"}],"version_history":[],"title":"Single-particle cryo electron microscopy of Integrin a4b7 bound to act1 fab","principal_investigator":[{"author_orcid":"0000-0003-3375-8937","middle_name":null,"organization":"Basic Sciences Division, Fred Hutchinson Cancer Center","street":"1100 Fairview Ave. N.","town_or_city":"Seattle","state_or_province":"Washington","post_or_zip":"98109","telephone":null,"fax":null,"first_name":"Jeremy","last_name":"Hollis","email":"jhollis [at] fredhutch.org","country":"United States","entry":"EMPIAR-13947"}],"status":"REL","deposition_date":"2026-09-10","release_date":"2026-10-07","obsolete_date":null,"update_date":"2026-10-07","corresponding_author":{"author":{"author_orcid":"0000-0003-1909-5751","middle_name":null,"organization":"Basic Sciences Division, Fred Hutchinson Cancer Center","street":"1100 Fairview Ave. N.","town_or_city":"Seattle","state_or_province":"Washington","post_or_zip":"98109","first_name":"Melody","last_name":"Campbell","country":"United States"}},"authors":[{"author":{"name":"Hollis JA","author_orcid":"0000-0003-3375-8937"}},{"author":{"name":"Campbell MG","author_orcid":"0000-0003-1909-5751"}}],"cross_references":["EMD-79037"],"biostudies_references":[],"idr_references":[],"empiar_references":[],"citation":[{"authors":[{"name":"Hollis JA","author_orcid":"0000-0003-3375-8937"},{"name":"Campbell MG","author_orcid":"0000-0003-1909-5751"}],"editors":[],"published":false,"j_or_nj_citation":false,"title":"Integrin a4b7 bound to act1 fab vedolizumab","volume":null,"country":"","first_page":null,"last_page":null,"year":null,"language":null,"doi":null,"pubmedid":null,"details":null,"book_chapter_title":null,"publisher":"","publication_location":"","journal":null,"journal_abbreviation":null,"issue":null,"preprint":null}],"dataset_size":"1.6 TB","experiment_type":"EMDB","scale":"molecule","entry_doi":"10.6019/EMPIAR-13947"}}