{"EMPIAR-13921":{"imagesets":[{"segmentations":[],"name":"Aligned CryoET stacks","directory":"data/processing/control_process/emClarity/fixedStacks","category":"tilt series","header_format":"MRC","data_format":"MRC","num_images_or_tilt_series":56,"frames_per_image":1,"frame_range_min":null,"frame_range_max":null,"voxel_type":"32 BIT FLOAT","pixel_width":1.501,"pixel_height":1.501,"micrographs_file_pattern":"","picked_particles_file_pattern":"","picked_particles_directory":"","details":"","image_width":"4096","image_height":"4096"}],"workflow_file":null,"grant_references":[{"funding_body":"National Institutes of Health (NIH)","code":"U54AI170791","country":"United States"},{"funding_body":"National Institutes of Health (NIH)","code":"R21AI184080","country":"United States"},{"funding_body":"Wellcome Trust","code":"206422/Z/17/Z","country":"United Kingdom"},{"funding_body":"Wellcome Trust","code":"311427/Z/24/Z","country":"United Kingdom"},{"funding_body":"European Research Council (ERC)","code":"101021133","country":"European Union"},{"funding_body":"CAMS Innovation Fund for Medical Sciences (CIFMS)","code":"2024-I2M-2-001-1","country":"China"},{"funding_body":"Ministry of Education (MoE, China)","code":"JYB2025XDXM502","country":"China"},{"funding_body":"National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS)","code":"P20GM103446","country":"United States"},{"funding_body":"National Institutes of Health (NIH)","code":"S10OD028725","country":"United States"}],"version_history":[],"title":"STA structure of CA hexamer from HIV-1 CA-NC tube","principal_investigator":[{"author_orcid":"0000-0003-1803-691X","middle_name":null,"organization":"The University of Oxford","street":"Structure biology","town_or_city":"Oxford","state_or_province":"Oxfordshire","post_or_zip":"OX3 7BN","telephone":"+441865 287723","fax":null,"first_name":"Peijun","last_name":"Zhang","email":"peijun.zhang [at] strubi.ox.ac.uk","country":"United Kingdom","entry":"EMPIAR-13921"},{"author_orcid":"0000-0003-1171-6816","middle_name":"R.","organization":"Department of Chemistry & Biochemistry University of Delaware","street":"177 Brown Laboratory","town_or_city":"Newark","state_or_province":"DE","post_or_zip":"19716","telephone":null,"fax":null,"first_name":"Juan","last_name":"Perilla","email":"jperilla [at] udel.edu","country":"United States","entry":"EMPIAR-13921"}],"status":"REL","deposition_date":"2026-09-07","release_date":"2026-09-11","obsolete_date":null,"update_date":"2026-09-11","corresponding_author":{"author":{"author_orcid":"0000-0003-1803-691X","middle_name":null,"organization":"The University of Oxford","street":"Structure biology","town_or_city":"Oxford","state_or_province":"Oxfordshire","post_or_zip":"OX3 7BN","first_name":"Peijun","last_name":"Zhang","country":"United Kingdom"}},"authors":[{"author":{"name":"Zhu Y","author_orcid":null}},{"author":{"name":"Rey SJ","author_orcid":null}},{"author":{"name":"Shen J","author_orcid":"0000-0002-1883-3057"}},{"author":{"name":"Perilla RJ","author_orcid":"0000-0003-1171-6816"}},{"author":{"name":"Zhang P","author_orcid":"0000-0003-1803-691X"}}],"cross_references":["EMD-54042"],"biostudies_references":[],"idr_references":[],"empiar_references":[],"citation":[{"authors":[{"name":"Zhu Y","author_orcid":null},{"name":"Rey JS","author_orcid":null},{"name":"Shen J","author_orcid":"0000-0002-1883-3057"},{"name":"Perilla JR","author_orcid":"0000-0003-1171-6816"},{"name":"Zhang P","author_orcid":"0000-0003-1803-691X"}],"editors":[],"published":false,"j_or_nj_citation":true,"title":"MxB N-Terminus Adopts a Stable α-Helix to Engage the HIV-1 Capsid Trimer Interface","volume":null,"country":"","first_page":null,"last_page":null,"year":null,"language":"English","doi":"10.64898/2026.05.07.723526","pubmedid":null,"details":"We present a structural characterization of the CA lattice in complex with the MxB N-terminal fragment using cryo-electron tomography and subtomogram averaging. Combining cryoEM structures with EM-guided all-atom molecular dynamics simulations, we identify residue-specific interactions between MxB and the CA trimer interfaces.","book_chapter_title":null,"publisher":null,"publication_location":null,"journal":"","journal_abbreviation":"","issue":null,"preprint":false}],"dataset_size":"140.6 GB","experiment_type":"EMDB","scale":"molecule","entry_doi":"10.6019/EMPIAR-13921"}}