{"EMPIAR-13787":{"imagesets":[{"segmentations":[],"name":"Structure and function of a near fully- activated intermediate GPCR-Gαβγ complex","directory":"data","category":"micrographs - multiframe","header_format":"TIFF","data_format":"TIFF","num_images_or_tilt_series":8875,"frames_per_image":79,"frame_range_min":1,"frame_range_max":79,"voxel_type":"UNSIGNED BYTE","pixel_width":0.835,"pixel_height":0.835,"micrographs_file_pattern":"data/mbi_*/*.tif","picked_particles_file_pattern":"","picked_particles_directory":"","details":"The raw micrographs include data from the same protein collected across four grids. The first three datasets were acquired on Quantifoil Au grids, and the fourth was acquired on an UltrAu grid. All four datasets were combined for the final reconstruction.","image_width":"5760","image_height":"4092"}],"workflow_file":null,"grant_references":[{"funding_body":"National Institutes of Health (NIH)","code":"5R35GM140847","country":"United States"},{"funding_body":"National Institutes of Health (NIH)","code":"1R01GM149659","country":"United States"},{"funding_body":"National Institutes of Health (NIH)","code":"1R21ES035378","country":"United States"},{"funding_body":"National Institutes of Health (NIH)","code":"5R01GM132572","country":"United States"},{"funding_body":"National Institutes of Health (NIH)","code":"S10OD020054","country":"United States"}],"version_history":[],"title":"Cryo-EM micrographs of a near fully-activated intermediate A2AR-mini-Gαβγ complex","principal_investigator":[{"author_orcid":"0000-0001-9535-0369","middle_name":null,"organization":"Department of Biochemistry and Biophysics, University of California, San Francisco","street":"600 16th Street","town_or_city":"San Francisco","state_or_province":"California","post_or_zip":"94143","telephone":null,"fax":null,"first_name":"Yifan","last_name":"Cheng","email":"Yifan.Cheng [at] ucsf.edu","country":"United States","entry":"EMPIAR-13787"}],"status":"REL","deposition_date":"2025-09-29","release_date":"2026-07-28","obsolete_date":null,"update_date":"2026-07-28","corresponding_author":{"author":{"author_orcid":"0000-0001-9535-0369","middle_name":null,"organization":"Department of Biochemistry and Biophysics, University of California, San Francisco","street":"600 16th Street","town_or_city":"San Francisco","state_or_province":"California","post_or_zip":"94143","first_name":"Yifan","last_name":"Cheng","country":"United States"}},"authors":[{"author":{"name":"Bi M","author_orcid":"0000-0001-6358-1867"}},{"author":{"name":"Wang X","author_orcid":"0000-0002-9686-2072"}},{"author":{"name":"Wang J","author_orcid":null}},{"author":{"name":"Xu J","author_orcid":null}},{"author":{"name":"Sun W","author_orcid":null}},{"author":{"name":"Adediwura VA","author_orcid":null}},{"author":{"name":"Miao Y","author_orcid":"0000-0003-3714-1395"}},{"author":{"name":"Cheng Y","author_orcid":"0000-0001-9535-0369"}},{"author":{"name":"Ye L","author_orcid":"0000-0003-0818-2972"}}],"cross_references":["EMD-47952","EMD-47953","EMD-47951"],"biostudies_references":[],"idr_references":[],"empiar_references":[],"citation":[{"authors":[{"name":"Bi M","author_orcid":"0000-0001-6358-1867"},{"name":"Wang X","author_orcid":"0000-0002-9686-2072"},{"name":"Wang J","author_orcid":null},{"name":"Xu J","author_orcid":"0000-0002-1600-583X"},{"name":"Sun W","author_orcid":"0000-0001-6957-2507"},{"name":"Adediwura VA","author_orcid":"0009-0008-3337-2747"},{"name":"Miao Y","author_orcid":"0000-0003-3714-1395"},{"name":"Cheng Y","author_orcid":"0000-0001-9535-0369"},{"name":"Ye L","author_orcid":"0000-0003-0818-2972"}],"editors":[],"published":true,"j_or_nj_citation":true,"title":"Structure and function of a near fully-activated intermediate GPCR-Gαβγ complex","volume":"16","country":"United States","first_page":null,"last_page":null,"year":"2025","language":"English","doi":"10.1038/s41467-025-56434-4","pubmedid":"39875358","details":"The micrographs are raw micrographs in .tiff format","book_chapter_title":null,"publisher":null,"publication_location":null,"journal":"Nature communications","journal_abbreviation":"Nat Commun","issue":"1","preprint":false}],"dataset_size":"2.4 TB","experiment_type":"EMDB","scale":"molecule","related_pdb_entries":["9ee9","9eea","9ee8"],"entry_doi":"10.6019/EMPIAR-13787"}}