{"EMPIAR-13749":{"imagesets":[{"segmentations":[],"name":"Cryo Electron Microscopy micrographs of multidrug resistance-associated protein 2 (MRP2) EQ Mutant bound to ATP","directory":"data","category":"micrographs - multiframe","header_format":"TIFF","data_format":"TIFF","num_images_or_tilt_series":7532,"frames_per_image":50,"frame_range_min":null,"frame_range_max":null,"voxel_type":"UNSIGNED 16 BIT INTEGER","pixel_width":0.676,"pixel_height":0.676,"micrographs_file_pattern":"data/20220909_hMRP2_EQ_219_*.tif","picked_particles_file_pattern":"","picked_particles_directory":"","details":"This dataset contains gain-corrected movies of the multidrug resistance-associated protein 2 (MRP2) E1462Q mutant bound to ATP. The pixel size is 0.676 Angstrom. This dataset corresponds to both the inward-facing and outward-facing ATP-bound structures (EMD-44833 and EMD-44911).","image_width":"11520","image_height":"8184"}],"workflow_file":null,"grant_references":[{"funding_body":"Howard Hughes Medical Institute (HHMI)","code":"N/A","country":"United States"}],"version_history":[],"title":"Cryo Electron Microscopy micrographs of multidrug resistance-associated protein 2 (MRP2) EQ Mutant bound to ATP","principal_investigator":[{"author_orcid":"0000-0003-2075-4283","middle_name":null,"organization":"The Rockefeller University, Howard Hughes Medical Institute","street":"1230 York Ave","town_or_city":"New York","state_or_province":"New York","post_or_zip":"10065","telephone":null,"fax":null,"first_name":"Jue","last_name":"Chen","email":"juechen [at] rockefeller.edu","country":"United States","entry":"EMPIAR-13749"}],"status":"REL","deposition_date":"2026-06-09","release_date":"2026-07-10","obsolete_date":null,"update_date":"2026-07-10","corresponding_author":{"author":{"author_orcid":"0000-0003-2075-4283","middle_name":null,"organization":"Rockefeller University, Howard Hughes Medical Institute","street":"1230 York Ave","town_or_city":"New York","state_or_province":"NY","post_or_zip":"10065","first_name":"Jue","last_name":"Chen","country":"United States"}},"authors":[{"author":{"name":"Koide EK","author_orcid":"0000-0002-8289-1542"}},{"author":{"name":"Pietz HLP","author_orcid":"0000-0003-4792-5708"}},{"author":{"name":"Beltran JB","author_orcid":null}},{"author":{"name":"Chen JC","author_orcid":"0000-0003-2075-4283"}}],"cross_references":["EMD-44911","EMD-44833"],"biostudies_references":[],"idr_references":[],"empiar_references":[],"citation":[{"authors":[{"name":"Koide EK","author_orcid":"0000-0002-8289-1542"},{"name":"Pietz HLP","author_orcid":"0000-0003-4792-5708"},{"name":"Beltran JB","author_orcid":null},{"name":"Chen JC","author_orcid":"0000-0003-2075-4283"}],"editors":[],"published":true,"j_or_nj_citation":true,"title":"Structural basis for the transport and regulation mechanism of the multidrug resistance-associated protein 2","volume":"484","country":"United States","first_page":null,"last_page":null,"year":"2025","language":"English","doi":"10.1038/s41467-024-55810-w","pubmedid":"39779684","details":null,"book_chapter_title":null,"publisher":null,"publication_location":null,"journal":"Nature Communications","journal_abbreviation":"Nat Commun","issue":"16","preprint":false}],"dataset_size":"4.0 TB","experiment_type":"EMDB","scale":"molecule","related_pdb_entries":["9buk","9br2"],"entry_doi":"10.6019/EMPIAR-13749"}}