{"EMPIAR-13747":{"imagesets":[{"segmentations":[],"name":"Unaligned multiframe micrographs of ISCro4-DBL-TBL-tDNA-dDNA synaptic complex","directory":"data","category":"micrographs - multiframe","header_format":"TIFF","data_format":"TIFF","num_images_or_tilt_series":7189,"frames_per_image":37,"frame_range_min":null,"frame_range_max":null,"voxel_type":"UNSIGNED BYTE","pixel_width":0.65,"pixel_height":0.65,"micrographs_file_pattern":"data","picked_particles_file_pattern":"","picked_particles_directory":"","details":"Total electron dose: 66.802 e–/Å2","image_width":"5760","image_height":"4092"},{"segmentations":[],"name":"Gain reference","directory":"data","category":"micrographs - single frame","header_format":"MRC","data_format":"MRC","num_images_or_tilt_series":1,"frames_per_image":1,"frame_range_min":null,"frame_range_max":null,"voxel_type":"UNSIGNED BYTE","pixel_width":0.65,"pixel_height":0.65,"micrographs_file_pattern":"data/250722_Bin2x_K3-20130003 Gain Ref. x1.m1.kv[300].mrc","picked_particles_file_pattern":"","picked_particles_directory":"","details":"","image_width":"5760","image_height":"4092"}],"workflow_file":null,"grant_references":[{"funding_body":"European Research Council (ERC)","code":"820152","country":"European Union"},{"funding_body":"Swiss National Science Foundation","code":"320030-228089","country":"Switzerland"}],"version_history":[],"title":"Cryo-EM structure of ISCro4-DBL-TBL-tDNA-dDNA synaptic complex","principal_investigator":[{"author_orcid":"0000-0002-7601-210X","middle_name":null,"organization":"Department of Biochemistry, University of Zurich","street":"Winterthurerstrasse 190","town_or_city":"Zurich","state_or_province":"ZH","post_or_zip":"8057","telephone":"+41446355572","fax":null,"first_name":"Martin","last_name":"Jinek","email":"jinek [at] bioc.uzh.ch","country":"Switzerland","entry":"EMPIAR-13747"}],"status":"REL","deposition_date":"2026-04-28","release_date":"2026-07-24","obsolete_date":null,"update_date":"2026-07-24","corresponding_author":{"author":{"author_orcid":"0000-0002-7601-210X","middle_name":null,"organization":"Department of Biochemistry, University of Zurich","street":"Winterthurerstrasse 190","town_or_city":"Zurich","state_or_province":"ZH","post_or_zip":"8057","first_name":"Martin","last_name":"Jinek","country":"Switzerland"}},"authors":[{"author":{"name":"Pelea O.","author_orcid":"0000-0002-1968-9827"}},{"author":{"name":"Fernandez Carrera J.","author_orcid":"0009-0008-7602-1517"}},{"author":{"name":"Gerecke S. E.","author_orcid":"0009-0004-6629-036X"}},{"author":{"name":"Chanez C.","author_orcid":"0000-0002-3432-4375"}},{"author":{"name":"Jinek M.","author_orcid":"0000-0002-7601-210X"}}],"cross_references":["EMD-55572"],"biostudies_references":[],"idr_references":[],"empiar_references":[],"citation":[{"authors":[{"name":"Pelea O.","author_orcid":"0000-0002-1968-9827"},{"name":"Talas A.","author_orcid":"0000-0003-0851-8333"},{"name":"Fernandez Carrera J.","author_orcid":"0009-0008-7602-1517"},{"name":"Mathis N.","author_orcid":"0000-0002-4051-8344"},{"name":"van der Venn L.","author_orcid":"0000-0003-0158-1225"},{"name":"Yeh C. D.","author_orcid":"0000-0002-2707-6035"},{"name":"Kulcsár P. I.","author_orcid":"0000-0002-7783-5108"},{"name":"Marquart K. F.","author_orcid":"0000-0001-7393-4398"},{"name":"Weber Y.","author_orcid":"0000-0002-0914-8541"},{"name":"Gerecke S. E.","author_orcid":"0009-0004-6629-036X"},{"name":"Harvey-Seutcheu I. F.","author_orcid":"0009-0004-3417-003X"},{"name":"Mailänder D.","author_orcid":"0009-0002-8033-4926"},{"name":"Pfleiderer M. M.","author_orcid":"0000-0002-2369-5824"},{"name":"Chanez C.","author_orcid":"0000-0002-3432-4375"},{"name":"Corn J.","author_orcid":"0000-0002-7798-5309"},{"name":"Schwank G.","author_orcid":"0000-0003-0767-2953"},{"name":"Jinek M.","author_orcid":"0000-0002-7601-210X"}],"editors":[],"published":true,"j_or_nj_citation":true,"title":"Programmable genome editing in human cells using RNA-guided bridge recombinases","volume":"391","country":"United States","first_page":"1122","last_page":"1122","year":"2026","language":"English","doi":"10.1126/science.adz188","pubmedid":"41642947","details":null,"book_chapter_title":null,"publisher":null,"publication_location":null,"journal":"Science","journal_abbreviation":"Science","issue":"6790","preprint":false}],"dataset_size":"1.2 TB","experiment_type":"EMDB","scale":"molecule","related_pdb_entries":["9t56"],"entry_doi":"10.6019/EMPIAR-13747"}}