{"EMPIAR-13721":{"imagesets":[{"segmentations":[],"name":"20240719_Tomita_TUT4_3_data","directory":"data","category":"micrographs - multiframe","header_format":"TIFF","data_format":"TIFF","num_images_or_tilt_series":4296,"frames_per_image":50,"frame_range_min":1,"frame_range_max":50,"voxel_type":"UNSIGNED BYTE","pixel_width":null,"pixel_height":null,"micrographs_file_pattern":"","picked_particles_file_pattern":"","picked_particles_directory":"","details":"- Microscope: FEI TITAN Krios\n- Acceleration voltage (kV): 300\n- Spherical aberration (Cs) : 2.7\n- Defocus (nm): -800 to -1800\n- Magnification:105000\n- Detector: Gatan K3 BIOQUANTUM\n- Average electron dose per image (e-/A2): 50\n- Number of frames per image: 50\n- The pixel size in the image header (1 Å/px) is wrong. 0.83 Å/px is the calibrated value.\n- Please use 'gain.mrc' as a gain reference with y-flipping for CryoSPARC.","image_width":"5760","image_height":"4092"},{"segmentations":[],"name":"20240724_Tomita_TUT4_2_data","directory":"data","category":"micrographs - 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multiframe","header_format":"TIFF","data_format":"TIFF","num_images_or_tilt_series":6382,"frames_per_image":50,"frame_range_min":1,"frame_range_max":50,"voxel_type":"UNSIGNED BYTE","pixel_width":null,"pixel_height":null,"micrographs_file_pattern":"","picked_particles_file_pattern":"","picked_particles_directory":"","details":"- Microscope: FEI TITAN Krios\n- Acceleration voltage (kV): 300\n- Spherical aberration (Cs) : 2.7\n- Defocus (nm): -800 to -1800\n- Magnification:105000\n- Detector: Gatan K3 BIOQUANTUM\n- Average electron dose per image (e-/A2): 50\n- Number of frames per image: 50\n- The pixel size in the image header (1 Å/px) is wrong. 0.83 Å/px is the calibrated value.\n- Please use 'gain.mrc' as a gain reference with y-flipping for CryoSPARC.","image_width":"5760","image_height":"4092"},{"segmentations":[],"name":"20241129_Tomita_TUT4_gUUU_Au_2_data","directory":"data","category":"micrographs - multiframe","header_format":"TIFF","data_format":"TIFF","num_images_or_tilt_series":7290,"frames_per_image":50,"frame_range_min":1,"frame_range_max":50,"voxel_type":"UNSIGNED BYTE","pixel_width":null,"pixel_height":null,"micrographs_file_pattern":"","picked_particles_file_pattern":"","picked_particles_directory":"","details":"- Microscope: FEI TITAN Krios\n- Acceleration voltage (kV): 300\n- Spherical aberration (Cs) : 2.7\n- Defocus (nm): -800 to -1800\n- Magnification:105000\n- Detector: Gatan K3 BIOQUANTUM\n- Average electron dose per image (e-/A2): 50\n- Number of frames per image: 50\n- The pixel size in the image header (1 Å/px) is wrong. 0.83 Å/px is the calibrated value.\n- Please use 'gain.mrc' as a gain reference with y-flipping for CryoSPARC.","image_width":"5760","image_height":"4092"}],"workflow_file":null,"grant_references":[],"version_history":[],"title":"Cryo-EM structure of the hTUT4_mini:Lin28A:pre-let-7g_UUU complex","principal_investigator":[{"author_orcid":"0000-0002-7374-3898","middle_name":null,"organization":"Department of Computational Biology and Medical Sciences, The University of Tokyo","street":"5-1-5 Kashiwanoha","town_or_city":"Kashiwa-shi, Chiba-ken","state_or_province":null,"post_or_zip":"277-8562","telephone":null,"fax":null,"first_name":"Kozo","last_name":"Tomita","email":"kozo-tomita [at] edu.k.u-tokyo.ac.jp","country":"Japan","entry":"EMPIAR-13721"}],"status":"REL","deposition_date":"2025-10-17","release_date":"2026-10-06","obsolete_date":null,"update_date":"2026-10-06","corresponding_author":{"author":{"author_orcid":"0000-0002-7374-3898","middle_name":null,"organization":"Department of Computational Biology and Medical Sciences, The University of Tokyo","street":"5-1-5 Kashiwanoha","town_or_city":"Kashiwa-shi, Chiba-ken","state_or_province":null,"post_or_zip":"277-8562","first_name":"Kozo","last_name":"Tomita","country":"Japan"}},"authors":[{"author":{"name":"Han X","author_orcid":null}},{"author":{"name":"Yamashita S","author_orcid":"0000-0002-6970-8758"}},{"author":{"name":"Tomita K","author_orcid":"0000-0002-7374-3898"}}],"cross_references":["EMD-65642","EMD-65643"],"biostudies_references":[],"idr_references":[],"empiar_references":[],"citation":[{"authors":[{"name":"Han X","author_orcid":null},{"name":"Yamashita S","author_orcid":"0000-0002-6970-8758"},{"name":"Tomita K","author_orcid":"0000-0002-7374-3898"}],"editors":[],"published":true,"j_or_nj_citation":true,"title":"Mechanistic insights into Lin28-dependent oligo-uridylylation of pre-let-7 by TUT4","volume":"54","country":"","first_page":null,"last_page":null,"year":"2026","language":"English","doi":"10.1093/nar/gkaf1421","pubmedid":"41521656","details":null,"book_chapter_title":null,"publisher":null,"publication_location":null,"journal":"Nucleic acids research","journal_abbreviation":"Nucleic Acids Res","issue":"1","preprint":false}],"dataset_size":"7.7 TB","experiment_type":"EMDB","scale":"molecule","related_pdb_entries":["9w4r","9w4s"],"entry_doi":"10.6019/EMPIAR-13721"}}