{"EMPIAR-13635":{"imagesets":[{"segmentations":[],"name":"Unaligned movies of Autoinhibited P-Rex2 untilted part 1","directory":"data/PRex2_untilted_part1","category":"micrographs - multiframe","header_format":"EER","data_format":"EER","num_images_or_tilt_series":4800,"frames_per_image":40,"frame_range_min":null,"frame_range_max":null,"voxel_type":"BIT","pixel_width":0.7296,"pixel_height":0.7296,"micrographs_file_pattern":"","picked_particles_file_pattern":"","picked_particles_directory":"","details":"","image_width":"4096","image_height":"4096"},{"segmentations":[],"name":"Unaligned movies of Autoinhibited P-Rex2 untilted part 2","directory":"data/PRex2_untilted_part2","category":"micrographs - multiframe","header_format":"EER","data_format":"EER","num_images_or_tilt_series":3800,"frames_per_image":40,"frame_range_min":null,"frame_range_max":null,"voxel_type":"BIT","pixel_width":0.7296,"pixel_height":0.7296,"micrographs_file_pattern":"","picked_particles_file_pattern":"","picked_particles_directory":"","details":"","image_width":"4096","image_height":"4096"},{"segmentations":[],"name":"Unaligned movies of Autoinhibited P-Rex2 untilted part 3","directory":"data/PRex2_untilted_part3","category":"micrographs - multiframe","header_format":"EER","data_format":"EER","num_images_or_tilt_series":3469,"frames_per_image":40,"frame_range_min":null,"frame_range_max":null,"voxel_type":"BIT","pixel_width":0.7296,"pixel_height":0.7296,"micrographs_file_pattern":"","picked_particles_file_pattern":"","picked_particles_directory":"","details":"","image_width":"4096","image_height":"4096"},{"segmentations":[],"name":"Unaligned movies of Autoinhibited P-Rex2 35 degree tilt part 1","directory":"data/PRex2_35tilted_part1","category":"micrographs - multiframe","header_format":"EER","data_format":"EER","num_images_or_tilt_series":4537,"frames_per_image":40,"frame_range_min":null,"frame_range_max":null,"voxel_type":"BIT","pixel_width":0.7296,"pixel_height":0.7296,"micrographs_file_pattern":"","picked_particles_file_pattern":"","picked_particles_directory":"","details":"","image_width":"4096","image_height":"4096"},{"segmentations":[],"name":"Unaligned movies of Autoinhibited P-Rex2 35 degree tilt part 2","directory":"data/PRex2_35tilted_part2","category":"micrographs - multiframe","header_format":"EER","data_format":"EER","num_images_or_tilt_series":3184,"frames_per_image":40,"frame_range_min":null,"frame_range_max":null,"voxel_type":"BIT","pixel_width":0.7296,"pixel_height":0.7296,"micrographs_file_pattern":"","picked_particles_file_pattern":"","picked_particles_directory":"","details":"","image_width":"4096","image_height":"4096"}],"workflow_file":null,"grant_references":[{"funding_body":"National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS)","code":"R35GM146664","country":"United States"},{"funding_body":"National Institutes of Health (NIH)","code":"R24GM154185","country":"United States"}],"version_history":[],"title":"Cryo-electron microscopy structure of autoinhibited P-Rex2","principal_investigator":[{"author_orcid":"0000-0002-0277-7652","middle_name":null,"organization":"University of California - Davis, Department of Molecular and Cellular Biology","street":"1 Shields Ave","town_or_city":"Davis","state_or_province":"California","post_or_zip":"95616","telephone":null,"fax":null,"first_name":"Jennifer","last_name":"Cash","email":"jcash [at] ucdavis.edu","country":"United States","entry":"EMPIAR-13635"}],"status":"REL","deposition_date":"2026-04-14","release_date":"2026-07-17","obsolete_date":null,"update_date":"2026-07-17","corresponding_author":{"author":{"author_orcid":"0000-0002-0277-7652","middle_name":null,"organization":"University of California - Davis, Department of Molecular and Cellular Biology","street":"1 Shields Ave","town_or_city":"Davis","state_or_province":"California","post_or_zip":"95616","first_name":"Jennifer","last_name":"Cash","country":"United States"}},"authors":[{"author":{"name":"Anderson LK","author_orcid":"0000-0001-7909-6380"}},{"author":{"name":"Cash JN","author_orcid":"0000-0002-0277-7652"}}],"cross_references":["EMD-74550","EMD-74548","EMD-74547","EMD-74549"],"biostudies_references":[],"idr_references":[],"empiar_references":[],"citation":[{"authors":[{"name":"Anderson LK","author_orcid":"0000-0001-7909-6380"},{"name":"Marde R","author_orcid":null},{"name":"Muma G","author_orcid":null},{"name":"Nayak V","author_orcid":null},{"name":"Phan C","author_orcid":null},{"name":"Li S","author_orcid":null},{"name":"Cash JN","author_orcid":"0000-0002-0277-7652"}],"editors":[],"published":true,"j_or_nj_citation":true,"title":"The Rho guanine-nucleotide exchange factor P-Rex2 exhibits structural and regulatory features distinct from the related RhoGEF P-Rex1","volume":null,"country":"","first_page":null,"last_page":null,"year":"2026","language":"English","doi":"10.1016/j.jbc.2026.113229","pubmedid":"42248461","details":null,"book_chapter_title":null,"publisher":null,"publication_location":null,"journal":"The Journal of biological chemistry","journal_abbreviation":"J Biol Chem","issue":null,"preprint":false}],"dataset_size":"9.4 TB","experiment_type":"EMDB","scale":"molecule","related_pdb_entries":["9zq7"],"entry_doi":"10.6019/EMPIAR-13635"}}