{"EMPIAR-13591":{"imagesets":[{"segmentations":[],"name":"Raw and unaligned multi frame movies for rat SLCO2A1 bound to losartan.","directory":"data","category":"micrographs - multiframe","header_format":"TIFF","data_format":"TIFF","num_images_or_tilt_series":26341,"frames_per_image":40,"frame_range_min":null,"frame_range_max":null,"voxel_type":"UNSIGNED BYTE","pixel_width":null,"pixel_height":null,"micrographs_file_pattern":"data","picked_particles_file_pattern":"","picked_particles_directory":"","details":"The micrographs are the raw movie frames (4092x5760) collected on a 300kV Titan Krios microscope. The datasets are organised into 3 sets with following parameters:\nSet I: 8575 movies, Total dose 40.2 e/Å^2, Pixel size 0.832Å, TIFF format. No tilt series.\nSet II: 4106 movies, Total dose 49.2 e/Å^2, Pixel size 0.832Å, TIFF format. No tilt series.\nSet III: 13,660 movies, Total dose 46.22 e/Å^2 , Pixel size 0.832Å, TIFF format. No tilt series.","image_width":null,"image_height":null}],"workflow_file":null,"grant_references":[{"funding_body":"Wellcome Trust","code":"215519/Z/19/Z","country":"United Kingdom"},{"funding_body":"Wellcome Trust","code":"219531/Z/19/Z","country":"United Kingdom"},{"funding_body":"Biotechnology and Biological Sciences Research Council (BBSRC)","code":"BB/Z517215/1","country":"United Kingdom"},{"funding_body":"Engineering and Physical Sciences Research Council","code":"EP/X035603/1","country":"United Kingdom"},{"funding_body":"Japan Society for the Promotion of Science (JSPS)","code":"24K09819","country":"Japan"},{"funding_body":"Japan Society for the Promotion of Science (JSPS)","code":"22K15295","country":"Japan"}],"version_history":[],"title":"Cryo-EM structure of rat SLCO2A1 bound to losartan.","principal_investigator":[{"author_orcid":"0000-0001-7432-2270","middle_name":null,"organization":"Department of Biochemistry, University of Oxford","street":"South Parks Road","town_or_city":"Oxford","state_or_province":"Oxfordshire","post_or_zip":"OX1 3QU","telephone":null,"fax":null,"first_name":"Simon","last_name":"Newstead","email":"simon.newstead [at] bioch.ox.ac.uk","country":"United Kingdom","entry":"EMPIAR-13591"}],"status":"REL","deposition_date":"2026-05-19","release_date":"2026-06-23","obsolete_date":null,"update_date":"2026-06-23","corresponding_author":{"author":{"author_orcid":"0000-0003-0045-964X","middle_name":null,"organization":"Department of Biochemistry, University of Oxford","street":"South Parks Road","town_or_city":"Oxford","state_or_province":"Oxfordshire","post_or_zip":"OX1 3QU","first_name":"Chitra","last_name":"Joshi","country":"United Kingdom"}},"authors":[{"author":{"name":"Joshi C","author_orcid":"0000-0003-0045-964X"}},{"author":{"name":"Newstead S","author_orcid":"0000-0001-7432-2270"}}],"cross_references":["EMD-53483"],"biostudies_references":[],"idr_references":[],"empiar_references":[],"citation":[{"authors":[{"name":"Joshi C","author_orcid":"0000-0003-0045-964X"},{"name":"Deme JC","author_orcid":"0000-0001-8811-9871"},{"name":"Nakamura Y","author_orcid":"0000-0003-3658-1663"},{"name":"Hsu WT","author_orcid":null},{"name":"Goult JD","author_orcid":null},{"name":"Kato T","author_orcid":null},{"name":"Parker JL","author_orcid":"0000-0003-2964-2720"},{"name":"Biggin PC","author_orcid":"0000-0001-5100-8836"},{"name":"Lea SM","author_orcid":"0000-0001-9287-8053"},{"name":"Nakanishi T","author_orcid":"0000-0002-6561-7138"},{"name":"Newstead S","author_orcid":"0000-0001-7432-2270"}],"editors":[],"published":true,"j_or_nj_citation":true,"title":"Structural basis for prostaglandin and drug transport via SLCO2A1","volume":"17","country":"United Kingdom","first_page":null,"last_page":null,"year":"2026","language":"English","doi":"10.1038/s41467-026-70227-3","pubmedid":"41862483","details":"The micrographs are the raw movie frames (4092x5760) collected on a 300kV Titan Krios microscope. The datasets are organised into 3 sets with following parameters:\nSet I: 8575 movies, Total dose 40.2 e/Å^2, Pixel size 0.832Å, TIFF format. No tilt series.\nSet II: 4106 movies, Total dose 49.2 e/Å^2, Pixel size 0.832Å, TIFF format. No tilt series.\nSet III: 13,660 movies, Total dose 46.22 e/Å^2 , Pixel size 0.832Å, TIFF format. No tilt series.","book_chapter_title":null,"publisher":null,"publication_location":null,"journal":"Nature communications","journal_abbreviation":"Nat Commun","issue":"1","preprint":false}],"dataset_size":"5.0 TB","experiment_type":"EMDB","scale":"molecule","related_pdb_entries":["9r0i"],"entry_doi":"10.6019/EMPIAR-13591"}}