{"EMPIAR-13566":{"imagesets":[{"segmentations":[],"name":"Raw, unaligned, gain-corrected frames of primary human T cells","directory":"data/raw_data/frames","category":"tilt series","header_format":"MRC","data_format":"MRC","num_images_or_tilt_series":14,"frames_per_image":10,"frame_range_min":null,"frame_range_max":null,"voxel_type":"SIGNED 16 BIT INTEGER","pixel_width":1.895,"pixel_height":1.895,"micrographs_file_pattern":"","picked_particles_file_pattern":"","picked_particles_directory":"","details":"The mdoc metadata files are also provided.","image_width":"4096","image_height":"4096"},{"segmentations":[],"name":"Tilt cleaned, dose-filtered tilt-series of primary human T cells","directory":"data/input_stacks","category":"tilt series","header_format":"MRC","data_format":"MRC","num_images_or_tilt_series":14,"frames_per_image":1,"frame_range_min":null,"frame_range_max":null,"voxel_type":"32 BIT FLOAT","pixel_width":1.895,"pixel_height":1.895,"micrographs_file_pattern":"","picked_particles_file_pattern":"","picked_particles_directory":"","details":"These tilt stacks were used for tomogram reconstruction in IMOD and novaCTF. The relevant alignment files (.xf and .tlt) are provided in the alignment_files folder.","image_width":"4096","image_height":"4096"},{"segmentations":[],"name":"Reconstructed tomograms (4x binning) of primary human T cells","directory":"data/bin4_rec","category":"reconstructed volumes","header_format":"MRC","data_format":"MRC","num_images_or_tilt_series":14,"frames_per_image":1,"frame_range_min":null,"frame_range_max":null,"voxel_type":"SIGNED 16 BIT INTEGER","pixel_width":7.58,"pixel_height":7.58,"micrographs_file_pattern":"","picked_particles_file_pattern":"","picked_particles_directory":"","details":"All tomograms were reconstructed in IMOD with 4x binning and a sirt-like filter. Tomogram 019 was additionally denoised with cryoCARE and IsoNet2.","image_width":"1024","image_height":"1024"}],"workflow_file":null,"grant_references":[{"funding_body":"Max Planck Society","code":"NA","country":"Germany"},{"funding_body":"Chan Zuckerberg Initiative","code":"2021-234666","country":"United States"},{"funding_body":"German Research Foundation (DFG)","code":"240245660","country":"Germany"}],"version_history":[],"title":"In situ cryo-ET dataset of primary human T cells","principal_investigator":[{"author_orcid":"0000-0002-7397-1321","middle_name":null,"organization":"Max Planck Institute of Biophysics","street":"Max-von-Laue-Straße 3","town_or_city":"Frankfurt am Main","state_or_province":"Hessen","post_or_zip":"60438","telephone":null,"fax":null,"first_name":"Martin","last_name":"Beck","email":"Martin.Beck [at] biophys.mpg.de","country":"Germany","entry":"EMPIAR-13566"}],"status":"REL","deposition_date":"2026-05-14","release_date":"2026-06-25","obsolete_date":null,"update_date":"2026-06-25","corresponding_author":{"author":{"author_orcid":"0000-0002-7397-1321","middle_name":null,"organization":"Max Planck Institute of Biophysics","street":"Max-von-Laue-Straße 3","town_or_city":"Frankfurt am Main","state_or_province":"Hessen","post_or_zip":"60438","first_name":"Martin","last_name":"Beck","country":"Germany"}},"authors":[{"author":{"name":"Kreysing JP","author_orcid":"0000-0002-4770-6313"}},{"author":{"name":"Penzo C","author_orcid":"0000-0002-0558-0759"}},{"author":{"name":"Lusic M","author_orcid":"0000-0002-0120-3569"}},{"author":{"name":"Beck M","author_orcid":"0000-0002-7397-1321"}}],"cross_references":["EMD-58100","EMD-58101"],"biostudies_references":[],"idr_references":[],"empiar_references":[],"citation":[{"authors":[{"name":"Kreysing JP","author_orcid":"0000-0002-4770-6313"},{"name":"Cruz-Leon S","author_orcid":"0000-0003-1256-2206"},{"name":"Betz J","author_orcid":null},{"name":"Penzo C","author_orcid":null},{"name":"Majtner T","author_orcid":"0000-0002-5279-8806"},{"name":"Schreiber M","author_orcid":"0009-0008-4485-4792"},{"name":"Turonova B","author_orcid":"0000-0002-5457-4478"},{"name":"Lusic M","author_orcid":"0000-0002-0120-3569"},{"name":"Hummer G","author_orcid":"0000-0001-7768-746X"},{"name":"Beck M","author_orcid":"0000-0002-7397-1321"}],"editors":[],"published":true,"j_or_nj_citation":true,"title":"Molecular architecture of heterochromatin at the nuclear periphery of primary human cells","volume":null,"country":"","first_page":null,"last_page":null,"year":"2025","language":"English","doi":"10.1101/2025.04.09.647790","pubmedid":null,"details":"The data was collected using a dose-symmetric scheme starting from +8 degree pre-tilt and covering a range from -52 to +68 degrees, with a tilt increment of 2 degrees.","book_chapter_title":null,"publisher":null,"publication_location":null,"journal":"bioRxiv","journal_abbreviation":"","issue":null,"preprint":true}],"dataset_size":"332.0 GB","experiment_type":"EMDB","scale":"cell","entry_doi":"10.6019/EMPIAR-13566"}}