{"EMPIAR-13517":{"imagesets":[{"segmentations":[],"name":"Unaligned multi-frame micrographs of Kir6.2+SUR1 KATP channels bound to Aekatperone and ATP","directory":"data","category":"micrographs - multiframe","header_format":"TIFF","data_format":"TIFF","num_images_or_tilt_series":31513,"frames_per_image":74,"frame_range_min":1,"frame_range_max":74,"voxel_type":"UNSIGNED BYTE","pixel_width":0.52575,"pixel_height":0.52575,"micrographs_file_pattern":"data/tif*/*.tif","picked_particles_file_pattern":"","picked_particles_directory":"","details":"","image_width":"11520","image_height":"8184"}],"workflow_file":null,"grant_references":[{"funding_body":"National Institutes of Health/National Institute of Diabetes and Digestive and Kidney Disease (NIH/NIDDK)","code":"DK066485","country":"United States"},{"funding_body":"National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS)","code":"GM129547","country":"United States"}],"version_history":[],"title":"Raw multi-frame images of SUR1/Kir6.2 ATP-sensitive potassium channel in the presence of Aekatperone and ATP","principal_investigator":[{"author_orcid":"0000-0002-8230-8820","middle_name":null,"organization":"Department of Chemical Physiology and Biochemistry, Oregon Health & Science University, United States","street":"3181 SW Sam Jackson Park Rd; Medical Research Building rm. 624A","town_or_city":"Portland","state_or_province":"Oregon","post_or_zip":"97239","telephone":null,"fax":null,"first_name":"Show-Ling","last_name":"Shyng","email":"shyngs [at] ohsu.edu","country":"United States","entry":"EMPIAR-13517"}],"status":"REL","deposition_date":"2025-09-15","release_date":"2026-05-05","obsolete_date":null,"update_date":"2026-05-05","corresponding_author":{"author":{"author_orcid":"0000-0002-2105-7175","middle_name":"M","organization":"Department of Chemical Physiology and Biochemistry, Oregon Health & Science University, United States","street":"3181 SW Sam Jackson Park Rd; Medical Research Building rm. 624","town_or_city":"Portland","state_or_province":"Oregon","post_or_zip":"97239","first_name":"Camden","last_name":"Driggers","country":"United States"}},"authors":[{"author":{"name":"Driggers CM","author_orcid":"0000-0002-2105-7175"}},{"author":{"name":"Elsheikh A","author_orcid":"0000-0001-7360-9309"}},{"author":{"name":"Shyng SL","author_orcid":"0000-0002-8230-8820"}}],"cross_references":["EMD-46820"],"biostudies_references":[],"idr_references":[],"empiar_references":[],"citation":[{"authors":[{"name":"Elsheikh A","author_orcid":"0000-0001-7360-9309"},{"name":"Driggers CM","author_orcid":"0000-0002-2105-7175"},{"name":"Truong HH","author_orcid":null},{"name":"Yang Z","author_orcid":"0000-0003-4686-0869"},{"name":"Allen J","author_orcid":null},{"name":"Henriksen NM","author_orcid":null},{"name":"Walczewska-Szewc K","author_orcid":"0000-0001-6422-6138"},{"name":"Shyng SL","author_orcid":"0000-0002-8230-8820"}],"editors":[],"published":true,"j_or_nj_citation":true,"title":"AI-based discovery and cryoEM structural elucidation of a K<sub>ATP</sub> channel pharmacochaperone","volume":"13","country":"","first_page":"RP103159","last_page":"RP103159","year":"2025","language":"English","doi":"10.7554/elife.103159","pubmedid":"40135739","details":"These are all raw multi-frame images, without curation, alignment or correction, which were collected in April and June of 2023 on PNCC Krios #3 (K3) from Ultrathin C Film Lacey Carbon, 400 mesh, Cu grids with  SUR1/Kir6.2 ATP-sensitive potassium channels in the presence of Aekatperone and ATP","book_chapter_title":null,"publisher":null,"publication_location":null,"journal":"eLife","journal_abbreviation":"Elife","issue":"RP103159","preprint":false}],"dataset_size":"16.3 TB","experiment_type":"EMDB","scale":"molecule","related_pdb_entries":["9dfx"],"entry_doi":"10.6019/EMPIAR-13517"}}