{"EMPIAR-13424":{"imagesets":[{"segmentations":[],"name":"Cryo-EM structure of the aspartate:alanine antiporter AspT mutant L60C","directory":"data","category":"micrographs - multiframe","header_format":"TIFF","data_format":"TIFF","num_images_or_tilt_series":8800,"frames_per_image":60,"frame_range_min":1,"frame_range_max":60,"voxel_type":"UNSIGNED 16 BIT INTEGER","pixel_width":0.788,"pixel_height":0.788,"micrographs_file_pattern":"","picked_particles_file_pattern":"","picked_particles_directory":"","details":"- Microscope: JEOL CRYO ARM 300\n- Pixel size: 0.788 Ang/pixel\n- Voltage: 300 kV\n- Spherical aberration: 2.7\n- Dose rate: 1.0 e / A**2 / frame\n- Gain_file: CountCDSRef_20210521L60CV2sec_289-1_000.mrc without rotation and Y-flipping\n- Please ignore the pixel size in the header; use 0.788 A/px.","image_width":"5760","image_height":"4092"}],"workflow_file":null,"grant_references":[],"version_history":[],"title":"Cryo-EM structure of the aspartate:alanine antiporter AspT mutant L60","principal_investigator":[{"author_orcid":"0000-0003-2001-1949","middle_name":null,"organization":"The Advanced Research Center for Innovations in Next-Generation Medicine (INGEM), Tohoku University;Tohoku Medical Megabank Organization, Tohoku University","street":"4F Tohoku Medical Megabank Building, 2-1 Seiryo-machi, Aoba-ku","town_or_city":"Sendai","state_or_province":"Miyagi","post_or_zip":"980-8573","telephone":"+81-22-274-2371","fax":null,"first_name":"Seizo","last_name":"Koshiba","email":"seizo.koshiba.b3 [at] tohoku.ac.jp","country":"Japan","entry":"EMPIAR-13424"}],"status":"REL","deposition_date":"2025-10-01","release_date":"2026-04-08","obsolete_date":null,"update_date":"2026-04-08","corresponding_author":{"author":{"author_orcid":"0000-0002-0032-9688","middle_name":null,"organization":"Graduate School of Information Sciences, Tohoku University","street":"Aoba 6-3-09, Aramaki, Aoba-ku","town_or_city":"Sendai","state_or_province":"Miyagi","post_or_zip":"980-8579","first_name":"Takeshi","last_name":"Kawabata","country":"Japan"}},"authors":[{"author":{"name":"Nanatani K","author_orcid":"0000-0002-1825-0097"}},{"author":{"name":"Kanno R","author_orcid":null}},{"author":{"name":"Kawabata T","author_orcid":"0000-0002-0032-9688"}},{"author":{"name":"Watanabe S","author_orcid":null}},{"author":{"name":"Hidaka M","author_orcid":"0000-0003-3458-1707"}},{"author":{"name":"Yamanaka T","author_orcid":null}},{"author":{"name":"Toda K","author_orcid":null}},{"author":{"name":"Fujiki T","author_orcid":null}},{"author":{"name":"Kunii K","author_orcid":null}},{"author":{"name":"Miyamoto A","author_orcid":null}},{"author":{"name":"Chiba F","author_orcid":null}},{"author":{"name":"Ogasawara S","author_orcid":"0000-0001-6908-9953"}},{"author":{"name":"Murata T","author_orcid":"0000-0002-5748-4670"}},{"author":{"name":"Humbel BM","author_orcid":null}},{"author":{"name":"Inaba K","author_orcid":null}},{"author":{"name":"Mitsuoka K","author_orcid":null}},{"author":{"name":"Guan L","author_orcid":"0000-0002-2274-361X"}},{"author":{"name":"Abe K","author_orcid":"0000-0001-5344-3794"}},{"author":{"name":"Yamamoto M","author_orcid":"0000-0002-9073-9436"}},{"author":{"name":"Koshiba S","author_orcid":"0000-0003-2001-1949"}}],"cross_references":["","","","Error","500","{metadata={error-class=org.apache.solr.core.SolrCoreInitializationException,root-error-class=java.nio.file.NoSuchFileException},msg=SolrCore","'emdb'","is","not","available","due","to","init","failure:","Error","opening","new","searcher,trace=org.apache.solr.core.SolrCoreInitializationException:","SolrCore","'emdb'","is","not","available","due","to","init","failure:","Error","opening","new","searcher","at","org.apache.solr.core.CoreContainer.getCore(CoreContainer.java:1740)","at","org.apache.solr.servlet.HttpSolrCall.init(HttpSolrCall.java:253)","at","org.apache.solr.servlet.HttpSolrCall.call(HttpSolrCall.java:538)","at","org.apache.solr.servlet.SolrDispatchFilter.doFilter(SolrDispatchFilter.java:419)","at","org.apache.solr.servlet.SolrDispatchFilter.doFilter(SolrDispatchFilter.java:351)","at","org.eclipse.jetty.servlet.ServletHandler$CachedChain.doFilter(ServletHandler.java:1602)","at","org.eclipse.jetty.servlet.ServletHandler.doHandle(ServletHandler.java:540)","at","org.eclipse.jetty.server.handler.ScopedHandler.handle(ScopedHandler.java:146)","at","org.eclipse.jetty.security.SecurityHandler.handle(SecurityHandler.java:548)","at","org.eclipse.jetty.server.handler.HandlerWrapper.handle(HandlerWrapper.java:132)","at","org.eclipse.jetty.server.handler.ScopedHandler.nextHandle(ScopedHandler.java:257)","at","org.eclipse.jetty.server.session.SessionHandler.doHandle(SessionHandler.java:1711)","at","org.eclipse.jetty.server.handler.ScopedHandler.nextHandle(ScopedHandler.java:255)","at","org.eclipse.jetty.server.handler.ContextHandler.doHandle(ContextHandler.java:1347)","at","org.eclipse.jetty.server.handler.ScopedHandler.nextScope(ScopedHandler.java:203)","at","org.eclipse.jetty.servlet.ServletHandler.doScope(ServletHandler.java:480)","at","org.eclipse.jetty.server.session.SessionHandler.doScope(SessionHandler.java:1678)","at","org.eclipse.jetty.server.handler.ScopedHandler.nextScope(ScopedHandler.java:201)","at","org.eclipse.jetty.server.handler.ContextHandler.doScope(ContextHandler.java:1249)","at","org.eclipse.jetty.server.handler.ScopedHandler.handle(ScopedHandler.java:144)","at","org.eclipse.jetty.server.handler.ContextHandlerCollection.handle(ContextHandlerCollection.java:220)","at","org.eclipse.jetty.server.handler.HandlerCollection.handle(HandlerCollection.java:152)","at","org.eclipse.jetty.server.handler.HandlerWrapper.handle(HandlerWrapper.java:132)","at","org.eclipse.jetty.rewrite.handler.RewriteHandler.handle(RewriteHandler.java:335)","at","org.eclipse.jetty.server.handler.HandlerWrapper.handle(HandlerWrapper.java:132)","at","org.eclipse.jetty.server.Server.handle(Server.java:505)","at","org.eclipse.jetty.server.HttpChannel.handle(HttpChannel.java:370)","at","org.eclipse.jetty.server.HttpConnection.onFillable(HttpConnection.java:267)","at","org.eclipse.jetty.io.AbstractConnection$ReadCallback.succeeded(AbstractConnection.java:305)","at","org.eclipse.jetty.io.FillInterest.fillable(FillInterest.java:103)","at","org.eclipse.jetty.io.ChannelEndPoint$2.run(ChannelEndPoint.java:117)","at","org.eclipse.jetty.util.thread.strategy.EatWhatYouKill.runTask(EatWhatYouKill.java:333)","at","org.eclipse.jetty.util.thread.strategy.EatWhatYouKill.doProduce(EatWhatYouKill.java:310)","at","org.eclipse.jetty.util.thread.strategy.EatWhatYouKill.tryProduce(EatWhatYouKill.java:168)","at","org.eclipse.jetty.util.thread.strategy.EatWhatYouKill.run(EatWhatYouKill.java:126)","at","org.eclipse.jetty.util.thread.ReservedThreadExecutor$ReservedThread.run(ReservedThreadExecutor.java:366)","at","org.eclipse.jetty.util.thread.QueuedThreadPool.runJob(QueuedThreadPool.java:781)","at","org.eclipse.jetty.util.thread.QueuedThreadPool$Runner.run(QueuedThreadPool.java:917)","at","java.base/java.lang.Thread.run(Unknown","Source)","Caused","by:","org.apache.solr.common.SolrException:","Error","opening","new","searcher","at","org.apache.solr.core.SolrCore.<init>(SolrCore.java:1052)","at","org.apache.solr.core.SolrCore.<init>(SolrCore.java:881)","at","org.apache.solr.core.CoreContainer.createFromDescriptor(CoreContainer.java:1251)","at","org.apache.solr.core.CoreContainer.lambda$load$13(CoreContainer.java:765)","at","com.codahale.metrics.InstrumentedExecutorService$InstrumentedCallable.call(InstrumentedExecutorService.java:202)","at","java.base/java.util.concurrent.FutureTask.run(Unknown","Source)","at","org.apache.solr.common.util.ExecutorUtil$MDCAwareThreadPoolExecutor.lambda$execute$0(ExecutorUtil.java:210)","at","java.base/java.util.concurrent.ThreadPoolExecutor.runWorker(Unknown","Source)","at","java.base/java.util.concurrent.ThreadPoolExecutor$Worker.run(Unknown","Source)","...","1","more","Caused","by:","org.apache.solr.common.SolrException:","Error","opening","new","searcher","at","org.apache.solr.core.SolrCore.openNewSearcher(SolrCore.java:2162)","at","org.apache.solr.core.SolrCore.getSearcher(SolrCore.java:2282)","at","org.apache.solr.core.SolrCore.initSearcher(SolrCore.java:1112)","at","org.apache.solr.core.SolrCore.<init>(SolrCore.java:993)","...","9","more","Caused","by:","org.apache.lucene.index.CorruptIndexException:","Problem","reading","index.","(resource=/var/solr/data/emdb/data/restore.20260811200813409/_90bku.fdt)","at","org.apache.lucene.index.SegmentCoreReaders.<init>(SegmentCoreReaders.java:144)","at","org.apache.lucene.index.SegmentReader.<init>(SegmentReader.java:84)","at","org.apache.lucene.index.ReadersAndUpdates.getReader(ReadersAndUpdates.java:177)","at","org.apache.lucene.index.ReadersAndUpdates.getReadOnlyClone(ReadersAndUpdates.java:219)","at","org.apache.lucene.index.StandardDirectoryReader.open(StandardDirectoryReader.java:109)","at","org.apache.lucene.index.IndexWriter.getReader(IndexWriter.java:526)","at","org.apache.lucene.index.DirectoryReader.open(DirectoryReader.java:116)","at","org.apache.lucene.index.DirectoryReader.open(DirectoryReader.java:92)","at","org.apache.solr.core.StandardIndexReaderFactory.newReader(StandardIndexReaderFactory.java:39)","at","org.apache.solr.core.SolrCore.openNewSearcher(SolrCore.java:2126)","...","12","more","Caused","by:","java.nio.file.NoSuchFileException:","/var/solr/data/emdb/data/restore.20260811200813409/_90bku.fdt","at","java.base/sun.nio.fs.UnixException.translateToIOException(Unknown","Source)","at","java.base/sun.nio.fs.UnixException.rethrowAsIOException(Unknown","Source)","at","java.base/sun.nio.fs.UnixException.rethrowAsIOException(Unknown","Source)","at","java.base/sun.nio.fs.UnixFileSystemProvider.newFileChannel(Unknown","Source)","at","java.base/java.nio.channels.FileChannel.open(Unknown","Source)","at","java.base/java.nio.channels.FileChannel.open(Unknown","Source)","at","org.apache.lucene.store.MMapDirectory.openInput(MMapDirectory.java:238)","at","org.apache.lucene.store.NRTCachingDirectory.openInput(NRTCachingDirectory.java:181)","at","org.apache.lucene.codecs.compressing.CompressingStoredFieldsReader.<init>(CompressingStoredFieldsReader.java:150)","at","org.apache.lucene.codecs.compressing.CompressingStoredFieldsFormat.fieldsReader(CompressingStoredFieldsFormat.java:121)","at","org.apache.lucene.codecs.lucene50.Lucene50StoredFieldsFormat.fieldsReader(Lucene50StoredFieldsFormat.java:173)","at","org.apache.lucene.index.SegmentCoreReaders.<init>(SegmentCoreReaders.java:127)","...","21","more",",code=500}","","

HTTP","ERROR","500

","

Problem","accessing","/solr/emdb/select.","Reason:","

","{metadata={error-class=org.apache.solr.core.SolrCoreInitializationException,root-error-class=java.nio.file.NoSuchFileException},msg=SolrCore","'emdb'","is","not","available","due","to","init","failure:","Error","opening","new","searcher,trace=org.apache.solr.core.SolrCoreInitializationException:","SolrCore","'emdb'","is","not","available","due","to","init","failure:","Error","opening","new","searcher","at","org.apache.solr.core.CoreContainer.getCore(CoreContainer.java:1740)","at","org.apache.solr.servlet.HttpSolrCall.init(HttpSolrCall.java:253)","at","org.apache.solr.servlet.HttpSolrCall.call(HttpSolrCall.java:538)","at","org.apache.solr.servlet.SolrDispatchFilter.doFilter(SolrDispatchFilter.java:419)","at","org.apache.solr.servlet.SolrDispatchFilter.doFilter(SolrDispatchFilter.java:351)","at","org.eclipse.jetty.servlet.ServletHandler$CachedChain.doFilter(ServletHandler.java:1602)","at","org.eclipse.jetty.servlet.ServletHandler.doHandle(ServletHandler.java:540)","at","org.eclipse.jetty.server.handler.ScopedHandler.handle(ScopedHandler.java:146)","at","org.eclipse.jetty.security.SecurityHandler.handle(SecurityHandler.java:548)","at","org.eclipse.jetty.server.handler.HandlerWrapper.handle(HandlerWrapper.java:132)","at","org.eclipse.jetty.server.handler.ScopedHandler.nextHandle(ScopedHandler.java:257)","at","org.eclipse.jetty.server.session.SessionHandler.doHandle(SessionHandler.java:1711)","at","org.eclipse.jetty.server.handler.ScopedHandler.nextHandle(ScopedHandler.java:255)","at","org.eclipse.jetty.server.handler.ContextHandler.doHandle(ContextHandler.java:1347)","at","org.eclipse.jetty.server.handler.ScopedHandler.nextScope(ScopedHandler.java:203)","at","org.eclipse.jetty.servlet.ServletHandler.doScope(ServletHandler.java:480)","at","org.eclipse.jetty.server.session.SessionHandler.doScope(SessionHandler.java:1678)","at","org.eclipse.jetty.server.handler.ScopedHandler.nextScope(ScopedHandler.java:201)","at","org.eclipse.jetty.server.handler.ContextHandler.doScope(ContextHandler.java:1249)","at","org.eclipse.jetty.server.handler.ScopedHandler.handle(ScopedHandler.java:144)","at","org.eclipse.jetty.server.handler.ContextHandlerCollection.handle(ContextHandlerCollection.java:220)","at","org.eclipse.jetty.server.handler.HandlerCollection.handle(HandlerCollection.java:152)","at","org.eclipse.jetty.server.handler.HandlerWrapper.handle(HandlerWrapper.java:132)","at","org.eclipse.jetty.rewrite.handler.RewriteHandler.handle(RewriteHandler.java:335)","at","org.eclipse.jetty.server.handler.HandlerWrapper.handle(HandlerWrapper.java:132)","at","org.eclipse.jetty.server.Server.handle(Server.java:505)","at","org.eclipse.jetty.server.HttpChannel.handle(HttpChannel.java:370)","at","org.eclipse.jetty.server.HttpConnection.onFillable(HttpConnection.java:267)","at","org.eclipse.jetty.io.AbstractConnection$ReadCallback.succeeded(AbstractConnection.java:305)","at","org.eclipse.jetty.io.FillInterest.fillable(FillInterest.java:103)","at","org.eclipse.jetty.io.ChannelEndPoint$2.run(ChannelEndPoint.java:117)","at","org.eclipse.jetty.util.thread.strategy.EatWhatYouKill.runTask(EatWhatYouKill.java:333)","at","org.eclipse.jetty.util.thread.strategy.EatWhatYouKill.doProduce(EatWhatYouKill.java:310)","at","org.eclipse.jetty.util.thread.strategy.EatWhatYouKill.tryProduce(EatWhatYouKill.java:168)","at","org.eclipse.jetty.util.thread.strategy.EatWhatYouKill.run(EatWhatYouKill.java:126)","at","org.eclipse.jetty.util.thread.ReservedThreadExecutor$ReservedThread.run(ReservedThreadExecutor.java:366)","at","org.eclipse.jetty.util.thread.QueuedThreadPool.runJob(QueuedThreadPool.java:781)","at","org.eclipse.jetty.util.thread.QueuedThreadPool$Runner.run(QueuedThreadPool.java:917)","at","java.base/java.lang.Thread.run(Unknown","Source)","Caused","by:","org.apache.solr.common.SolrException:","Error","opening","new","searcher","at","org.apache.solr.core.SolrCore.<init>(SolrCore.java:1052)","at","org.apache.solr.core.SolrCore.<init>(SolrCore.java:881)","at","org.apache.solr.core.CoreContainer.createFromDescriptor(CoreContainer.java:1251)","at","org.apache.solr.core.CoreContainer.lambda$load$13(CoreContainer.java:765)","at","com.codahale.metrics.InstrumentedExecutorService$InstrumentedCallable.call(InstrumentedExecutorService.java:202)","at","java.base/java.util.concurrent.FutureTask.run(Unknown","Source)","at","org.apache.solr.common.util.ExecutorUtil$MDCAwareThreadPoolExecutor.lambda$execute$0(ExecutorUtil.java:210)","at","java.base/java.util.concurrent.ThreadPoolExecutor.runWorker(Unknown","Source)","at","java.base/java.util.concurrent.ThreadPoolExecutor$Worker.run(Unknown","Source)","...","1","more","Caused","by:","org.apache.solr.common.SolrException:","Error","opening","new","searcher","at","org.apache.solr.core.SolrCore.openNewSearcher(SolrCore.java:2162)","at","org.apache.solr.core.SolrCore.getSearcher(SolrCore.java:2282)","at","org.apache.solr.core.SolrCore.initSearcher(SolrCore.java:1112)","at","org.apache.solr.core.SolrCore.<init>(SolrCore.java:993)","...","9","more","Caused","by:","org.apache.lucene.index.CorruptIndexException:","Problem","reading","index.","(resource=/var/solr/data/emdb/data/restore.20260811200813409/_90bku.fdt)","at","org.apache.lucene.index.SegmentCoreReaders.<init>(SegmentCoreReaders.java:144)","at","org.apache.lucene.index.SegmentReader.<init>(SegmentReader.java:84)","at","org.apache.lucene.index.ReadersAndUpdates.getReader(ReadersAndUpdates.java:177)","at","org.apache.lucene.index.ReadersAndUpdates.getReadOnlyClone(ReadersAndUpdates.java:219)","at","org.apache.lucene.index.StandardDirectoryReader.open(StandardDirectoryReader.java:109)","at","org.apache.lucene.index.IndexWriter.getReader(IndexWriter.java:526)","at","org.apache.lucene.index.DirectoryReader.open(DirectoryReader.java:116)","at","org.apache.lucene.index.DirectoryReader.open(DirectoryReader.java:92)","at","org.apache.solr.core.StandardIndexReaderFactory.newReader(StandardIndexReaderFactory.java:39)","at","org.apache.solr.core.SolrCore.openNewSearcher(SolrCore.java:2126)","...","12","more","Caused","by:","java.nio.file.NoSuchFileException:","/var/solr/data/emdb/data/restore.20260811200813409/_90bku.fdt","at","java.base/sun.nio.fs.UnixException.translateToIOException(Unknown","Source)","at","java.base/sun.nio.fs.UnixException.rethrowAsIOException(Unknown","Source)","at","java.base/sun.nio.fs.UnixException.rethrowAsIOException(Unknown","Source)","at","java.base/sun.nio.fs.UnixFileSystemProvider.newFileChannel(Unknown","Source)","at","java.base/java.nio.channels.FileChannel.open(Unknown","Source)","at","java.base/java.nio.channels.FileChannel.open(Unknown","Source)","at","org.apache.lucene.store.MMapDirectory.openInput(MMapDirectory.java:238)","at","org.apache.lucene.store.NRTCachingDirectory.openInput(NRTCachingDirectory.java:181)","at","org.apache.lucene.codecs.compressing.CompressingStoredFieldsReader.<init>(CompressingStoredFieldsReader.java:150)","at","org.apache.lucene.codecs.compressing.CompressingStoredFieldsFormat.fieldsReader(CompressingStoredFieldsFormat.java:121)","at","org.apache.lucene.codecs.lucene50.Lucene50StoredFieldsFormat.fieldsReader(Lucene50StoredFieldsFormat.java:173)","at","org.apache.lucene.index.SegmentCoreReaders.<init>(SegmentCoreReaders.java:127)","...","21","more",",code=500}

","",""],"biostudies_references":[],"idr_references":[],"empiar_references":[],"citation":[{"authors":[{"name":"Nanatani K","author_orcid":"0000-0002-1825-0097"},{"name":"Guan L","author_orcid":"0000-0002-2274-361X"},{"name":"Kanno R","author_orcid":null},{"name":"Kawabata T","author_orcid":"0000-0002-0032-9688"},{"name":"Watanabe S","author_orcid":null},{"name":"Katsube S","author_orcid":null},{"name":"Hariharan P","author_orcid":"0000-0002-6020-1547"},{"name":"Hidaka M","author_orcid":"0000-0003-3458-1707"},{"name":"Yamanaka T","author_orcid":null},{"name":"Toda K","author_orcid":null},{"name":"Fujiki T","author_orcid":null},{"name":"Kunii K","author_orcid":null},{"name":"Miyamoto A","author_orcid":null},{"name":"Chiba F","author_orcid":null},{"name":"Ogasawara S","author_orcid":"0000-0001-6908-9953"},{"name":"Murata T","author_orcid":"0000-0002-5748-4670"},{"name":"Inaba K","author_orcid":null},{"name":"Mitsuoka K","author_orcid":null},{"name":"Abe K","author_orcid":"0000-0001-5344-3794"},{"name":"Yamamoto M","author_orcid":"0000-0002-9073-9436"},{"name":"Koshiba S","author_orcid":"0000-0003-2001-1949"}],"editors":[],"published":true,"j_or_nj_citation":true,"title":"Elucidation of the structure and molecular mechanisms of the aspartate antiporter","volume":"8","country":"","first_page":null,"last_page":null,"year":"2025","language":"English","doi":"10.1038/s42003-025-08676-7","pubmedid":"40998974","details":"8800 movies in TIFF format","book_chapter_title":null,"publisher":null,"publication_location":null,"journal":"Communications biology","journal_abbreviation":"Commun Biol","issue":"1","preprint":false}],"dataset_size":"2.2 TB","experiment_type":"EMDB","scale":"molecule","related_pdb_entries":["","414 Request-URI Too Large","","

414 Request-URI Too Large

","

nginx","",""],"entry_doi":"10.6019/EMPIAR-13424"}}