{"EMPIAR-13178":{"imagesets":[{"segmentations":[],"name":"Cryo-EM structure of human lipid phosphate phosphatase 1 complexed with PO4 in nanodiscs","directory":"data","category":"micrographs - multiframe","header_format":"TIFF","data_format":"TIFF","num_images_or_tilt_series":530,"frames_per_image":32,"frame_range_min":1,"frame_range_max":32,"voxel_type":"UNSIGNED BYTE","pixel_width":0.82,"pixel_height":0.82,"micrographs_file_pattern":"data","picked_particles_file_pattern":"","picked_particles_directory":"","details":"Raw cryo-EM dose-fractionated movies acquired on a Titan Krios equipped with a K3 direct electron detector. Movies were recorded as multi-frame TIFF stacks with approximately 32 frames per movie at a calibrated pixel size of 0.82 Å/pixel. The data are unaligned and unprocessed, intended for motion correction and downstream single-particle analysis.","image_width":"11520","image_height":"8184"}],"workflow_file":null,"grant_references":[{"funding_body":"National Natural Science Foundation of China (NSFC)","code":"32271241","country":"China"}],"version_history":[],"title":"Cryo-EM structure of human lipid phosphate phosphatase 1 complexed with PO4 in nanodiscs","principal_investigator":[{"author_orcid":"0000-0001-9940-8003","middle_name":null,"organization":"University of Science and Technology of China","street":"Huangshan Road","town_or_city":"Hefei","state_or_province":"Anhui Province","post_or_zip":"230000","telephone":null,"fax":null,"first_name":"Hongwu","last_name":"Qian","email":"hongwuqian [at] ustc.edu.cn","country":"China","entry":"EMPIAR-13178"}],"status":"REL","deposition_date":"2025-12-08","release_date":"2026-01-28","obsolete_date":null,"update_date":"2026-01-28","corresponding_author":{"author":{"author_orcid":"0000-0001-9940-8003","middle_name":null,"organization":"university of science and technology of China","street":"Huangshan Road","town_or_city":"Hefei","state_or_province":"Anhui Province","post_or_zip":"230000","first_name":"Hongwu","last_name":"Qian","country":"China"}},"authors":[{"author":{"name":"Yang YM","author_orcid":"0009-0004-1453-8749"}},{"author":{"name":"Qian QHW","author_orcid":"0000-0001-9940-8003"}}],"cross_references":["EMD-65153"],"biostudies_references":[],"idr_references":[],"empiar_references":[],"citation":[{"authors":[{"name":"Yang M","author_orcid":"0009-0004-1453-8749"},{"name":"Sun C","author_orcid":null},{"name":"He Y","author_orcid":null},{"name":"Qian H","author_orcid":"0000-0001-9940-8003"}],"editors":[],"published":true,"j_or_nj_citation":true,"title":"Structural basis for the catalytic mechanism of human lipid phosphate phosphatases","volume":null,"country":"China","first_page":null,"last_page":null,"year":"2026","language":"English","doi":"10.1038/s41589-025-02121-w","pubmedid":"41513850","details":"The micrographs are the average, without any realignment, of 32 raw movie frames (accumulating 50 electron per squared angstrom in a 1.8 second exposure)","book_chapter_title":null,"publisher":null,"publication_location":null,"journal":"Nature chemical biology","journal_abbreviation":"Nat Chem Biol","issue":null,"preprint":false}],"dataset_size":"163.2 GB","experiment_type":"EMDB","scale":"molecule","related_pdb_entries":["9vl3"],"entry_doi":"10.6019/EMPIAR-13178"}}