{"EMPIAR-13122":{"imagesets":[{"segmentations":[],"name":"Unaligned mutli-frame raw frames of Connexin-46/50 in DMPC nanodiscs at low pH (control for return to neutral pH)","directory":"data/frames","category":"micrographs - multiframe","header_format":"TIFF","data_format":"TIFF","num_images_or_tilt_series":12423,"frames_per_image":50,"frame_range_min":null,"frame_range_max":null,"voxel_type":"UNSIGNED 16 BIT INTEGER","pixel_width":0.411,"pixel_height":0.411,"micrographs_file_pattern":"","picked_particles_file_pattern":"","picked_particles_directory":"","details":"","image_width":"11520","image_height":"8184"}],"workflow_file":null,"grant_references":[{"funding_body":"National Institutes of Health/National Eye Institute (NIH/NEI)","code":"R35GM124779","country":"United States"}],"version_history":[],"title":"Cryo-EM of connexin-46/50 in DMPC nanodiscs at low pH (Collection #5)","principal_investigator":[{"author_orcid":"0000-0001-5276-7690","middle_name":"Leon","organization":"Department of Chemical Physiology and Biochemistry, Vollum Institute, Oregon Health and Science University","street":"3181 SW Sam Jackson Park Road","town_or_city":"Portland","state_or_province":"Oregon","post_or_zip":"97239-3098","telephone":null,"fax":null,"first_name":"Steve","last_name":"Reichow","email":"reichow [at] ohsu.edu","country":"United States","entry":"EMPIAR-13122"}],"status":"REL","deposition_date":"2025-11-21","release_date":"2026-04-07","obsolete_date":null,"update_date":"2026-04-07","corresponding_author":{"author":{"author_orcid":"0009-0001-6804-1496","middle_name":"Michael","organization":"Department of Chemical Physiology and Biochemistry, Vollum Institute, Oregon Health and Science University","street":"3181 SW Sam Jackson Park Road","town_or_city":"Portland","state_or_province":"Oregon","post_or_zip":"97239-3098","first_name":"Joshua","last_name":"Jarodsky","country":"United States"}},"authors":[{"author":{"name":"Jarodsky JM","author_orcid":"0009-0001-6804-1496"}},{"author":{"name":"Myers JB","author_orcid":"0000-0002-7758-2649"}},{"author":{"name":"Reichow SL","author_orcid":"0000-0001-5276-7690"}}],"cross_references":["EMD-73965"],"biostudies_references":[],"idr_references":[],"empiar_references":[],"citation":[{"authors":[{"name":"Jarodsky JM","author_orcid":"0009-0001-6804-1496"},{"name":"Myers JB","author_orcid":"0000-0002-7758-2649"},{"name":"Reichow SL","author_orcid":"0000-0001-5276-7690"}],"editors":[],"published":true,"j_or_nj_citation":true,"title":"Reversible lipid-mediated pH-gating of connexin-46/50 by cryo-EM","volume":"17","country":"United States","first_page":null,"last_page":null,"year":"2026","language":"English","doi":"10.1038/s41467-026-68311-9","pubmedid":"41526355","details":null,"book_chapter_title":null,"publisher":null,"publication_location":null,"journal":"Nature communications","journal_abbreviation":"Nat Commun","issue":"1","preprint":false}],"dataset_size":"4.3 TB","experiment_type":"EMDB","scale":"molecule","related_pdb_entries":["9za3"],"entry_doi":"10.6019/EMPIAR-13122"}}