{"EMPIAR-13076":{"imagesets":[{"segmentations":[],"name":"Unaligned multi-frame micrographs of Drosophila Insulin Receptor ectodomain complex with DILP2 hormone","directory":"data/Grid1","category":"micrographs - multiframe","header_format":"EER","data_format":"EER","num_images_or_tilt_series":1068,"frames_per_image":630,"frame_range_min":null,"frame_range_max":null,"voxel_type":"UNSIGNED 32 BIT INTEGER","pixel_width":0.574,"pixel_height":0.574,"micrographs_file_pattern":"data/Grid1/Images-Disc1/GridSquare_22153923/Data/FoilHole_22279651_Data_22195976_14_20240322_203035_EER.eer","picked_particles_file_pattern":"","picked_particles_directory":"","details":"Title: cryo-EM data for  Drosophila Insulin Receptor ectodomain with DILP2 hormone\nMicroscope/Detector: TFS Glacios / Falcon IV\nGrid 1 contains 1068 of total \n12103 movies, corresponding to the micrograms selected after CTFFIND\nCalibrated pixel size: 0.574 A\nFlux: 6.27 e-/pixel/s\nTotal fluence 50 e-/A^2\nData were collected from two separate grids corresponding to different stages of the project timeline described in the associated publication.\nThe two datasets are provided in separate subdirectories (Grid 1 and Grid 2) under the EMPIAR root\nData from both datasets were joined and used at the final stages of the project,resulting in two different structures: entry emd-52236, PDB 9HKT, 3.76A and enry EMD-52310, PDB 9HNI, 6.25A\nthree other files under EMPIAR root are the following\nemd-52236_run_data.star contains metadata for 127081 particles from Refine3D for EMD-52236, pdb 9HKT\nemd-52310_run_data.star contains metadata for 57317 particles from Refine3D for EMD-52310, pdb 9HNI\ndmirdilp2_GainReference.gain","image_width":"4096","image_height":"4096"},{"segmentations":[],"name":"Unaligned multi-frame micrographs of Drosophila Insulin Receptor ectodomain complex with DILP2 hormone","directory":"data/Grid2","category":"micrographs - multiframe","header_format":"EER","data_format":"EER","num_images_or_tilt_series":11035,"frames_per_image":630,"frame_range_min":null,"frame_range_max":null,"voxel_type":"UNSIGNED 32 BIT INTEGER","pixel_width":0.574,"pixel_height":0.574,"micrographs_file_pattern":"data/Grid2/Images-Disc1/GridSquare_22157047/Data/FoilHole_23547179_Data_22199156_1_20240323_182828_EER.eer","picked_particles_file_pattern":"","picked_particles_directory":"","details":"Same as described for Grid 1 (and README file), but contains the remaining 11035 micrographs","image_width":"4096","image_height":"4096"}],"workflow_file":null,"grant_references":[{"funding_body":"Biotechnology and Biological Sciences Research Council (BBSRC)","code":"BB/W003783/1","country":"United Kingdom"}],"version_history":[],"title":"cryo-EM data for Drosophila Insulin Receptor ectodomain with DILP2 hormone","principal_investigator":[{"author_orcid":"0000-0001-7426-8948","middle_name":"Marek","organization":"University of York","street":"Heslington","town_or_city":"York","state_or_province":"North Yorkshire","post_or_zip":"YO105DD","telephone":null,"fax":null,"first_name":"Andrjey","last_name":"Brzozowski","email":"marek.brzozowski [at] york.ac.uk","country":"United Kingdom","entry":"EMPIAR-13076"}],"status":"REL","deposition_date":"2025-10-23","release_date":"2026-05-31","obsolete_date":null,"update_date":"2026-05-31","corresponding_author":{"author":{"author_orcid":"0000-0002-0354-6119","middle_name":"V","organization":"University of York","street":"Heslington","town_or_city":"York","state_or_province":"North Yorkshire","post_or_zip":"YO105DD","first_name":"Olga","last_name":"Moroz","country":"United Kingdom"}},"authors":[{"author":{"name":"Shafi T","author_orcid":"0000-0001-8214-2579"}},{"author":{"name":"Moroz OV","author_orcid":"0000-0002-0354-6119"}},{"author":{"name":"Jenkins HT","author_orcid":"0000-0002-3302-6966"}},{"author":{"name":"Chechik M","author_orcid":"0000-0001-8413-4230"}},{"author":{"name":"Isupov MN","author_orcid":"0000-0001-6842-4289"}},{"author":{"name":"Brzozowski AM","author_orcid":"0000-0001-7426-8948"}}],"cross_references":["EMD-52236","EMD-52310"],"biostudies_references":[],"idr_references":[],"empiar_references":[],"citation":[{"authors":[{"name":"Shafi T","author_orcid":"0000-0001-8214-2579"},{"name":"Moroz OV","author_orcid":"0000-0002-0354-6119"},{"name":"Jenkins HT","author_orcid":"0000-0002-3302-6966"},{"name":"Chechik M","author_orcid":"0000-0001-8413-4230"},{"name":"Isupov MN","author_orcid":"0000-0001-6842-4289"},{"name":"Brzozowski AM","author_orcid":"0000-0001-7426-8948"}],"editors":[],"published":false,"j_or_nj_citation":true,"title":"Towards understanding of one receptor:many hormones paradigm: cryo-EM structures of Drosophila Insulin Receptor ectodomain with DILP2 hormone","volume":null,"country":"","first_page":null,"last_page":null,"year":null,"language":null,"doi":"10.1098/rsob.250351","pubmedid":null,"details":null,"book_chapter_title":null,"publisher":null,"publication_location":null,"journal":"","journal_abbreviation":"","issue":null,"preprint":false}],"dataset_size":"3.4 TB","experiment_type":"EMDB","scale":"molecule","related_pdb_entries":["9hkt","9hni"],"entry_doi":"10.6019/EMPIAR-13076"}}