{"EMPIAR-13070":{"imagesets":[{"segmentations":[],"name":"Unaligned multi-frame micrographs of VPS13C, non-tilted","directory":"data/0tilt","category":"micrographs - multiframe","header_format":"TIFF","data_format":"TIFF","num_images_or_tilt_series":4140,"frames_per_image":50,"frame_range_min":1,"frame_range_max":50,"voxel_type":"UNSIGNED BYTE","pixel_width":0.534,"pixel_height":0.534,"micrographs_file_pattern":"data/0tilt","picked_particles_file_pattern":"","picked_particles_directory":"","details":"Raw movies with 50 raw movie frames in TIFF format, collected with a 0° tilt  using SerialEM with a 2.896 second exposure time and in a total dose 42.7 e⁻/Ų. Requires flipping gain in Y when processed in CryoSPARC.","image_width":"11520","image_height":"8184"},{"segmentations":[],"name":"Unaligned multi-frame micrographs of VPS13C, 25° tilted","directory":"data/25tilt","category":"micrographs - multiframe","header_format":"TIFF","data_format":"TIFF","num_images_or_tilt_series":4914,"frames_per_image":50,"frame_range_min":1,"frame_range_max":50,"voxel_type":"UNSIGNED BYTE","pixel_width":0.534,"pixel_height":0.534,"micrographs_file_pattern":"data/25tilt","picked_particles_file_pattern":"","picked_particles_directory":"","details":"Raw movies with 50 raw movie frames in TIFF format, collected with a 25° tilt  using SerialEM with a 2.896 second exposure time and in a total dose 42.7 e⁻/Ų. Requires flipping gain in Y when processed in CryoSPARC.","image_width":"11520","image_height":"8184"}],"workflow_file":null,"grant_references":[{"funding_body":"Michael J. Fox Foundation","code":"ASAP-000580","country":"United States"}],"version_history":[],"title":"Raw images used to generate the structure of VPS13C in complex with calmodulin [ 0° tilt, 4140 multi-frame images and 25° tilt, 4914 multi-frame images each in TIFF format]","principal_investigator":[{"author_orcid":"0000-0001-9140-6150","middle_name":null,"organization":"Yale University, Department of Cell Biology","street":"333 Cedar St.","town_or_city":"New Haven","state_or_province":"CT","post_or_zip":"06511","telephone":null,"fax":null,"first_name":"Karin","last_name":"Reinisch","email":"karin.reinisch [at] yale.edu","country":"United States","entry":"EMPIAR-13070"}],"status":"REL","deposition_date":"2025-10-17","release_date":"2026-07-05","obsolete_date":null,"update_date":"2026-07-27","corresponding_author":{"author":{"author_orcid":"0009-0006-7086-3866","middle_name":null,"organization":"Yale University, Department of Cell Biology","street":"333 Cedar St.","town_or_city":"New Haven","state_or_province":"Connecticut","post_or_zip":"06511","first_name":"Dazhi","last_name":"Li","country":"United States"}},"authors":[{"author":{"name":"Li DL","author_orcid":"0009-0006-7086-3866"}}],"cross_references":["EMD-73373","EMD-73344","EMD-73345","EMD-73343"],"biostudies_references":[],"idr_references":[],"empiar_references":[],"citation":[{"authors":[{"name":"Li D","author_orcid":"0009-0006-7086-3866"},{"name":"Wang X","author_orcid":"0000-0003-1270-5123"},{"name":"Hao H","author_orcid":null},{"name":"Eden J","author_orcid":null},{"name":"Hu B","author_orcid":"0000-0002-1365-7381"},{"name":"Walsh EE","author_orcid":null},{"name":"Parson MAH","author_orcid":null},{"name":"Hamill S","author_orcid":null},{"name":"Li Y","author_orcid":null},{"name":"Chen G","author_orcid":null},{"name":"Burke JE","author_orcid":null},{"name":"De Camilli P","author_orcid":"0000-0001-9045-0723"},{"name":"Reinisch KM","author_orcid":"0000-0001-9140-6150"}],"editors":[],"published":true,"j_or_nj_citation":true,"title":"Cryo-EM structure of soluble VPS13C suggests its regulation by a conformational switch and by calmodulin","volume":null,"country":"","first_page":"S1097","last_page":"2765(26)00417","year":"2026","language":"English","doi":"10.1016/j.molcel.2026.06.028","pubmedid":"42413490","details":null,"book_chapter_title":null,"publisher":null,"publication_location":null,"journal":"Molecular cell","journal_abbreviation":"Mol Cell","issue":null,"preprint":false}],"dataset_size":"4.8 TB","experiment_type":"EMDB","scale":"molecule","related_pdb_entries":["9yrp","9yqq","9yqp"],"entry_doi":"10.6019/EMPIAR-13070"}}