{"EMPIAR-12867":{"imagesets":[{"segmentations":[],"name":"unaligned multi-frame micrographs of Human polymerase epsilon bound to PCNA and DNA with an in-situ generated mismatch","directory":"data/raw","category":"micrographs - multiframe","header_format":"TIFF","data_format":"TIFF","num_images_or_tilt_series":18426,"frames_per_image":50,"frame_range_min":null,"frame_range_max":null,"voxel_type":"UNSIGNED BYTE","pixel_width":0.414,"pixel_height":0.414,"micrographs_file_pattern":"data/raw","picked_particles_file_pattern":"","picked_particles_directory":"","details":"The micrographs are the average, without any realigment, of 50 raw movie frames (accumulating 60 electron per squared Angstrom in a 1.0 second exposure).","image_width":"11520","image_height":"8184"}],"workflow_file":null,"grant_references":[{"funding_body":"National Institutes of Health (NIH)","code":"GM148159","country":"United States"},{"funding_body":"National Institutes of Health (NIH)","code":"GM131754","country":"United States"}],"version_history":[],"title":"Human polymerase epsilon bound to PCNA and DNA with an in-situ-generated mismatch","principal_investigator":[{"author_orcid":"0000-0001-8085-8928","middle_name":null,"organization":"Department of Structural Biology  Van Andel institute","street":"333 Bostwick Ave. NE","town_or_city":"Grand Rapids","state_or_province":"MI","post_or_zip":"49503","telephone":"6162345306","fax":null,"first_name":"Huilin","last_name":"Li","email":"huili.li [at] vai.org","country":"United States","entry":"EMPIAR-12867"}],"status":"REL","deposition_date":"2025-06-20","release_date":"2025-12-03","obsolete_date":null,"update_date":"2026-03-03","corresponding_author":{"author":{"author_orcid":"0000-0001-8085-8928","middle_name":null,"organization":"Department of Structural Biology  Van Andel institute","street":"333 Bostwick Ave. NE","town_or_city":"Grand Rapids","state_or_province":"MI","post_or_zip":"49503","first_name":"Huilin","last_name":"Li","country":"United States"}},"authors":[{"author":{"name":"Wang FW","author_orcid":"0000-0002-6565-8095"}}],"cross_references":["EMD-49299","EMD-49301","EMD-49300"],"biostudies_references":[],"idr_references":[],"empiar_references":[],"citation":[{"authors":[{"name":"Wang F","author_orcid":"0000-0002-6565-8095"},{"name":"He Q","author_orcid":"0000-0002-8414-2430"},{"name":"O'Donnell ME","author_orcid":"0000-0001-9002-4214"},{"name":"Li H","author_orcid":"0000-0001-8085-8928"}],"editors":[],"published":true,"j_or_nj_citation":true,"title":"The proofreading mechanism of the human leading-strand DNA polymerase ε holoenzyme","volume":"122","country":"United States","first_page":null,"last_page":null,"year":"2025","language":"English","doi":"10.1073/pnas.2507232122","pubmedid":"40440070","details":"The micrographs are the average, without any realigmnet, of 50 raw movie frames (accumulating 60 electron per squared Angstrom in a 1.0 second exposure).","book_chapter_title":null,"publisher":null,"publication_location":null,"journal":"Proceedings of the National Academy of Sciences of the United States of America","journal_abbreviation":"Proc Natl Acad Sci U S A","issue":"22","preprint":false}],"dataset_size":"13.4 TB","experiment_type":"EMDB","scale":"molecule","related_pdb_entries":["9ne6","9ne8","9ne7"],"entry_doi":"10.6019/EMPIAR-12867"}}