{"EMPIAR-12772":{"imagesets":[{"segmentations":[],"name":"Unaligned multi-frame movies of Progesterone-bound DB3 Fab in complex with computationally designed DBPro1156_2 protein binder","directory":"data/Images-Disc1","category":"micrographs - multiframe","header_format":"MRC","data_format":"MRC","num_images_or_tilt_series":34507,"frames_per_image":60,"frame_range_min":null,"frame_range_max":null,"voxel_type":"32 BIT FLOAT","pixel_width":0.658,"pixel_height":0.658,"micrographs_file_pattern":"","picked_particles_file_pattern":"","picked_particles_directory":"","details":"","image_width":"4096","image_height":"4096"},{"segmentations":[],"name":"Aligned dose-weighted micrographs of Progesterone-bound DB3 Fab in complex with computationally designed DBPro1156_2 protein binder","directory":"data/DW","category":"micrographs - single frame","header_format":"MRC","data_format":"MRC","num_images_or_tilt_series":34507,"frames_per_image":1,"frame_range_min":null,"frame_range_max":null,"voxel_type":"32 BIT FLOAT","pixel_width":0.658,"pixel_height":0.658,"micrographs_file_pattern":"","picked_particles_file_pattern":"","picked_particles_directory":"","details":"","image_width":"4096","image_height":"4096"}],"workflow_file":null,"grant_references":[{"funding_body":"Swiss National Science Foundation","code":"310030197724","country":"Switzerland"}],"version_history":[],"title":"Progesterone-bound DB3 Fab in complex with computationally designed DBPro1156_2 protein binder","principal_investigator":[{"author_orcid":null,"middle_name":"E","organization":"LPDI, EPFL","street":null,"town_or_city":"Lausanne","state_or_province":null,"post_or_zip":"1015","telephone":null,"fax":null,"first_name":"Bruno","last_name":"Correia","email":"bruno.correia [at] epfl.ch","country":"Switzerland","entry":"EMPIAR-12772"}],"status":"REL","deposition_date":"2025-02-11","release_date":"2025-10-29","obsolete_date":null,"update_date":"2025-10-29","corresponding_author":{"author":{"author_orcid":"0000-0003-1560-5769","middle_name":null,"organization":"LPDI, EPFL","street":null,"town_or_city":"Lausanne","state_or_province":null,"post_or_zip":"1015","first_name":"Martin","last_name":"Pacesa","country":"Switzerland"}},"authors":[{"author":{"name":"Marchand A","author_orcid":null}},{"author":{"name":"Buckley S","author_orcid":null}},{"author":{"name":"Schneuing A","author_orcid":null}},{"author":{"name":"Pacesa M","author_orcid":"0000-0003-1560-5769"}},{"author":{"name":"Elia M","author_orcid":null}},{"author":{"name":"Gainza P","author_orcid":null}},{"author":{"name":"Elizarova E","author_orcid":null}},{"author":{"name":"Neeser RM","author_orcid":null}},{"author":{"name":"Lee PW","author_orcid":null}},{"author":{"name":"Reymond L","author_orcid":null}},{"author":{"name":"Miao Y","author_orcid":null}},{"author":{"name":"Scheller L","author_orcid":null}},{"author":{"name":"Georgeon S","author_orcid":null}},{"author":{"name":"Schmidt J","author_orcid":null}},{"author":{"name":"Schwaller P","author_orcid":null}},{"author":{"name":"Maerkl SJ","author_orcid":null}},{"author":{"name":"Bronstein M","author_orcid":null}},{"author":{"name":"Correia BE","author_orcid":null}}],"cross_references":["EMD-50522"],"biostudies_references":[],"idr_references":[],"empiar_references":[],"citation":[{"authors":[{"name":"Marchand A","author_orcid":"0000-0003-2864-0408"},{"name":"Buckley S","author_orcid":null},{"name":"Schneuing A","author_orcid":"0009-0000-9924-6921"},{"name":"Pacesa M","author_orcid":"0000-0003-1560-5769"},{"name":"Elia M","author_orcid":"0000-0002-8853-9734"},{"name":"Gainza P","author_orcid":null},{"name":"Elizarova E","author_orcid":null},{"name":"Neeser RM","author_orcid":"0000-0002-3289-2766"},{"name":"Lee PW","author_orcid":null},{"name":"Reymond L","author_orcid":"0000-0001-5282-9273"},{"name":"Miao Y","author_orcid":null},{"name":"Scheller L","author_orcid":"0000-0003-2490-4015"},{"name":"Georgeon S","author_orcid":null},{"name":"Schmidt J","author_orcid":null},{"name":"Schwaller P","author_orcid":"0000-0003-3046-6576"},{"name":"Maerkl SJ","author_orcid":"0000-0003-1917-5268"},{"name":"Bronstein M","author_orcid":"0000-0002-1262-7252"},{"name":"Correia BE","author_orcid":"0000-0002-7377-8636"}],"editors":[],"published":true,"j_or_nj_citation":true,"title":"Targeting protein-ligand neosurfaces with a generalizable deep learning tool","volume":null,"country":"","first_page":null,"last_page":null,"year":"2025","language":"English","doi":"10.1038/s41586-024-08435-4","pubmedid":"39814890","details":null,"book_chapter_title":null,"publisher":null,"publication_location":null,"journal":"Nature","journal_abbreviation":"Nature","issue":null,"preprint":false}],"dataset_size":"14.6 TB","experiment_type":"EMDB","scale":"molecule","related_pdb_entries":["9fkd"],"entry_doi":"10.6019/EMPIAR-12772"}}