{"EMPIAR-12721":{"imagesets":[{"segmentations":[],"name":"Unaligned multi-frame micrographs of human RNA Polymerase II elongation complex bound to the RECQL5 helicase in the presence of AMPPNP","directory":"data","category":"micrographs - multiframe","header_format":"TIFF","data_format":"TIFF","num_images_or_tilt_series":12100,"frames_per_image":50,"frame_range_min":null,"frame_range_max":null,"voxel_type":"UNSIGNED BYTE","pixel_width":1.048,"pixel_height":1.048,"micrographs_file_pattern":"","picked_particles_file_pattern":"","picked_particles_directory":"","details":"This dataset contains raw, uncorrected movies collected in non-CDS, non-super-resolution mode (collected using a Titan Krios G3i, 300 kV, spherical aberration 2.7 mm, total dose 50 e/A^2). The pixel size is 1.048 A. The directory also contains the gain reference file (CountRef_04092024_RECQL5_AMPPNP_161_0001_X+0Y+0-1.mrc 89.9 MB). This should not be rotated or flipped for processing in cryoSPARC.","image_width":"5760","image_height":"4092"}],"workflow_file":null,"grant_references":[{"funding_body":"Howard Hughes Medical Institute (HHMI)","code":"none","country":"United States"}],"version_history":[],"title":"Structural insights into transcriptional regulation by the helicase RECQL5","principal_investigator":[{"author_orcid":"0000-0001-9816-3681","middle_name":null,"organization":"University of California Berkeley","street":"University Dr","town_or_city":"Berkeley","state_or_province":"CA","post_or_zip":"94704","telephone":null,"fax":null,"first_name":"Eva","last_name":"Nogales","email":"enogales [at] lbl.gov","country":"United States","entry":"EMPIAR-12721"}],"status":"REL","deposition_date":"2025-04-22","release_date":"2025-05-30","obsolete_date":null,"update_date":"2025-05-30","corresponding_author":{"author":{"author_orcid":"0000-0001-9816-3681","middle_name":null,"organization":"University of California Berkeley","street":"University Dr","town_or_city":"Berkeley","state_or_province":"California","post_or_zip":"94706","first_name":"Eva","last_name":"Nogales","country":"United States"}},"authors":[{"author":{"name":"Florez Ariza AJ","author_orcid":"0000-0003-2429-4659"}},{"author":{"name":"Lue NZ","author_orcid":"0000-0002-4236-9127"}},{"author":{"name":"Grob P","author_orcid":"0000-0002-8330-8961"}},{"author":{"name":"Kaeser B","author_orcid":"0000-0002-6569-3608"}},{"author":{"name":"Fang J","author_orcid":"0009-0008-3181-3799"}},{"author":{"name":"Kassube SA","author_orcid":"0000-0003-4322-5886"}},{"author":{"name":"Nogales E","author_orcid":"0000-0001-9816-3681"}}],"cross_references":["EMD-48075"],"biostudies_references":[],"idr_references":[],"empiar_references":[],"citation":[{"authors":[{"name":"Florez Ariza AJ","author_orcid":"0000-0003-2429-4659"},{"name":"Lue NZ","author_orcid":"0000-0002-4236-9127"},{"name":"Grob P","author_orcid":null},{"name":"Kaeser B","author_orcid":null},{"name":"Fang J","author_orcid":null},{"name":"Kassube SA","author_orcid":null},{"name":"Nogales E","author_orcid":"0000-0001-9816-3681"}],"editors":[],"published":true,"j_or_nj_citation":true,"title":"Structural insights into transcriptional regulation by the helicase RECQL5","volume":null,"country":"","first_page":null,"last_page":null,"year":"2025","language":null,"doi":"10.1101/2025.01.29.634372","pubmedid":"39975028","details":null,"book_chapter_title":null,"publisher":null,"publication_location":null,"journal":"bioRxiv","journal_abbreviation":"","issue":null,"preprint":true}],"dataset_size":"3.2 TB","experiment_type":"EMDB","scale":"molecule","related_pdb_entries":["9ei3"],"entry_doi":"10.6019/EMPIAR-12721"}}