{"EMPIAR-12704":{"imagesets":[{"segmentations":[],"name":"Unaligned multiframe micrographs","directory":"data","category":"micrographs - multiframe","header_format":"EER","data_format":"EER","num_images_or_tilt_series":10488,"frames_per_image":50,"frame_range_min":null,"frame_range_max":null,"voxel_type":"UNSIGNED 16 BIT INTEGER","pixel_width":0.935,"pixel_height":0.935,"micrographs_file_pattern":"","picked_particles_file_pattern":"","picked_particles_directory":"","details":"Contains data collected from 2 grids during april 13 and april 20 of 2023","image_width":null,"image_height":null}],"workflow_file":null,"grant_references":[{"funding_body":"Michael J. Fox Foundation","code":"ASAP-000519","country":"United States"}],"version_history":[],"title":"Single particle Cryo EM of the C-terminal half LRRK2 I2020T mutant bound to MLi-2","principal_investigator":[{"author_orcid":"0000-0002-7732-7023","middle_name":null,"organization":"University of California San Diego","street":null,"town_or_city":"La Jolla","state_or_province":"California","post_or_zip":"92093","telephone":null,"fax":null,"first_name":"Andres","last_name":"Leschziner","email":"aleschziner [at] ucsd.edu","country":"United States","entry":"EMPIAR-12704"}],"status":"REL","deposition_date":"2025-04-10","release_date":"2025-10-09","obsolete_date":null,"update_date":"2025-10-09","corresponding_author":{"author":{"author_orcid":"0000-0002-7732-7023","middle_name":null,"organization":"University of California San Diego","street":null,"town_or_city":"La Jolla","state_or_province":"California","post_or_zip":"92093","first_name":"Andres","last_name":"Leschziner","country":"United States"}},"authors":[{"author":{"name":"Sanz Murillo M","author_orcid":"0000-0002-6175-9315"}},{"author":{"name":"Villagran Suarez A","author_orcid":"0000-0003-3400-2330"}},{"author":{"name":"Dederer V","author_orcid":"0009-0006-7557-5388"}},{"author":{"name":"Chatterjee D","author_orcid":null}},{"author":{"name":"Alegrio Louro J","author_orcid":"0000-0002-2800-923X"}},{"author":{"name":"Knapp S","author_orcid":"0000-0001-5995-6494"}},{"author":{"name":"Leschziner A","author_orcid":"0000-0002-7732-7023"}}],"cross_references":["EMD-41758"],"biostudies_references":[],"idr_references":[],"empiar_references":[],"citation":[{"authors":[{"name":"Sanz Murillo M","author_orcid":"0000-0002-6175-9315"},{"name":"Villagran Suarez A","author_orcid":"0000-0003-3400-2330"},{"name":"Dederer V","author_orcid":"0009-0006-7557-5388"},{"name":"Chatterjee D","author_orcid":null},{"name":"Alegrio Louro J","author_orcid":"0000-0002-2800-923X"},{"name":"Knapp S","author_orcid":"0000-0001-5995-6494"},{"name":"Mathea S","author_orcid":"0000-0001-8500-4569"},{"name":"Leschziner AE","author_orcid":"0000-0002-7732-7023"}],"editors":[],"published":true,"j_or_nj_citation":true,"title":"Inhibition of Parkinson's disease-related LRRK2 by type I and type II kinase inhibitors: Activity and structures","volume":"9","country":"","first_page":null,"last_page":null,"year":"2023","language":"English","doi":"10.1126/sciadv.adk6191","pubmedid":"38039358","details":"micrographs taken with a 0.822A/px with 44 frames with a total dose of 56.9","book_chapter_title":null,"publisher":null,"publication_location":null,"journal":"Science advances","journal_abbreviation":"Sci Adv","issue":"48","preprint":false},{"authors":[{"name":"Sanz Murillo M","author_orcid":"0000-0002-6175-9315"},{"name":"Villagran Suarez A","author_orcid":"0000-0003-3400-2330"},{"name":"Dederer V","author_orcid":"0009-0006-7557-5388"},{"name":"Chatterjee D","author_orcid":null},{"name":"Alegrio Louro J","author_orcid":"0000-0002-2800-923X"},{"name":"Knapp S","author_orcid":"0000-0001-5995-6494"},{"name":"Mathea S","author_orcid":"0000-0001-8500-4569"},{"name":"Leschziner AE","author_orcid":"0000-0002-7732-7023"}],"editors":[],"published":true,"j_or_nj_citation":true,"title":"Inhibition of Parkinson's disease-related LRRK2 by type I and type II kinase inhibitors: Activity and structures","volume":"9","country":"","first_page":null,"last_page":null,"year":"2023","language":"English","doi":"10.1126/sciadv.adk6191","pubmedid":"38039358","details":null,"book_chapter_title":null,"publisher":null,"publication_location":null,"journal":"Science advances","journal_abbreviation":"Sci Adv","issue":"48","preprint":false}],"dataset_size":"10.0 TB","experiment_type":"EMDB","scale":"molecule","related_pdb_entries":["8tzg"],"entry_doi":"10.6019/EMPIAR-12704"}}