{"EMPIAR-12700":{"imagesets":[{"segmentations":[],"name":"Cryo-EM structure of spMETTL16 in complex with U6 snRNA and SAM","directory":"data","category":"micrographs - multiframe","header_format":"TIFF","data_format":"TIFF","num_images_or_tilt_series":8497,"frames_per_image":50,"frame_range_min":1,"frame_range_max":50,"voxel_type":"UNSIGNED BYTE","pixel_width":0.83,"pixel_height":0.83,"micrographs_file_pattern":"","picked_particles_file_pattern":"","picked_particles_directory":"","details":"- Microscope: FEI TITAN Krios\n- Acceleration voltage (kV): 300\n- Spherical aberration (Cs): 2.7\n- Nominal Defocus (nm): -800 to -1800\n- Detector: Gatan K3 BIOQUANTUM\n- Average electron dose per image (e-/A2): 50\n- Please use gain.mrc as a gain reference.\n- In CryoSPARC, select \"flip gain ref in Y\".\n- 167 movies in missing.txt were not used in the processing leading to the deposited structure due to a data transfer glitch.","image_width":"5760","image_height":"4092"}],"workflow_file":null,"grant_references":[],"version_history":[],"title":"Cryo-EM structure of spMETTL16 in complex with U6 snRNA and SAM","principal_investigator":[{"author_orcid":"0000-0002-7374-3898","middle_name":null,"organization":"University of Tokyo","street":"Kashiwanoha 5-1-5","town_or_city":"Kashiwa","state_or_province":"Chiba","post_or_zip":"2778562","telephone":null,"fax":null,"first_name":"Kozo","last_name":"Tomita","email":"kozo-tomita [at] edu.k.u-tokyo.ac.jp","country":"Japan","entry":"EMPIAR-12700"}],"status":"REL","deposition_date":"2025-04-11","release_date":"2026-03-07","obsolete_date":null,"update_date":"2026-03-07","corresponding_author":{"author":{"author_orcid":"0000-0002-7374-3898","middle_name":null,"organization":"University of Tokyo","street":"Kashiwanoha 5-1-5","town_or_city":"Kashiwa","state_or_province":"Chiba","post_or_zip":"2778562","first_name":"Kozo","last_name":"Tomita","country":"Japan"}},"authors":[{"author":{"name":"Ju J","author_orcid":"0000-0003-3660-3375"}},{"author":{"name":"Tomita K","author_orcid":"0000-0002-7374-3898"}}],"cross_references":["EMD-63834"],"biostudies_references":[],"idr_references":[],"empiar_references":[],"citation":[{"authors":[{"name":"Ju J","author_orcid":"0000-0003-3660-3375"},{"name":"Tomita K","author_orcid":"0000-0002-7374-3898"}],"editors":[],"published":true,"j_or_nj_citation":true,"title":"Structures and mechanisms of U6 snRNA m<sup>6</sup>A modification by METTL16","volume":"16","country":"","first_page":null,"last_page":null,"year":"2025","language":"English","doi":"10.1038/s41467-025-63021-0","pubmedid":"40841561","details":null,"book_chapter_title":null,"publisher":null,"publication_location":null,"journal":"Nature communications","journal_abbreviation":"Nat Commun","issue":"1","preprint":false}],"dataset_size":"1.9 TB","experiment_type":"EMDB","scale":"molecule","related_pdb_entries":["9u48"],"entry_doi":"10.6019/EMPIAR-12700"}}