{"EMPIAR-12631":{"imagesets":[{"segmentations":[],"name":"Raw micrographs of Pannexin 1 containing c-terminal activating domain, stack 1/2","directory":"data","category":"micrographs - multiframe","header_format":"TIFF","data_format":"TIFF","num_images_or_tilt_series":3318,"frames_per_image":50,"frame_range_min":null,"frame_range_max":null,"voxel_type":"UNSIGNED BYTE","pixel_width":0.535,"pixel_height":0.535,"micrographs_file_pattern":"data","picked_particles_file_pattern":"","picked_particles_directory":"","details":"First of two (randomly organized) stacks of images used to generate EMD-45056. Raw unprocessed micrographs containing 50 frames over 50 e-/pix/sec. Gain is included in .mrc format and should be flipped upside down. Images were collected on a 300 kV Titan Krios with a K3 direct electron detector and BioQuantuum energy filter with a slit set to 15 eV. No objective aperture was used. Spherical aberration is 2.7.","image_width":"11520","image_height":"8184"}],"workflow_file":null,"grant_references":[{"funding_body":"National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS)","code":"R01GM114379","country":"United States"}],"version_history":[],"title":"Raw .tiff images of Panx1 containing c-terminal activating domain stack 1","principal_investigator":[{"author_orcid":"0000-0002-5005-2031","middle_name":null,"organization":"Cornell University","street":"930 Campus Rd","town_or_city":"Ithaca","state_or_province":"NY","post_or_zip":"14853","telephone":"6072533783","fax":null,"first_name":"Toshi","last_name":"Kawate","email":"tk499 [at] cornell.edu","country":"United States","entry":"EMPIAR-12631"}],"status":"REL","deposition_date":"2025-03-01","release_date":"2025-07-25","obsolete_date":null,"update_date":"2025-07-25","corresponding_author":{"author":{"author_orcid":"0000-0002-5005-2031","middle_name":null,"organization":"Cornell University","street":"930 Campus Rd","town_or_city":"Ithaca","state_or_province":"NY","post_or_zip":"14853","first_name":"Toshi","last_name":"Kawate","country":"United States"}},"authors":[{"author":{"name":"Ehrlich JJ","author_orcid":"0000-0002-8761-7198"}},{"author":{"name":"Kawate T","author_orcid":"0000-0002-5005-2031"}}],"cross_references":["EMD-45056"],"biostudies_references":[],"idr_references":[],"empiar_references":[],"citation":[{"authors":[{"name":"Henze E","author_orcid":null},{"name":"Ehrlich JJ","author_orcid":"0000-0002-8761-7198"},{"name":"Robertson JL","author_orcid":"0000-0002-5499-9943"},{"name":"Gelsleichter E","author_orcid":"0000-0002-5970-813X"},{"name":"Kawate T","author_orcid":"0000-0002-5005-2031"}],"editors":[],"published":true,"j_or_nj_citation":true,"title":"The C-terminal activating domain promotes pannexin 1 channel opening","volume":"121","country":"","first_page":null,"last_page":null,"year":"2024","language":"English","doi":"10.1073/pnas.2411898121","pubmedid":"39671183","details":"This is the first stack of raw .tiff micrographs making up EMD-45056. Images were collect on at 300 kV on a Titan Krios with K3 direct electron detector. Raw pixel size is 0.535, spherical aberration 2.7. Flip gain upside down.","book_chapter_title":null,"publisher":null,"publication_location":null,"journal":"Proceedings of the National Academy of Sciences of the United States of America","journal_abbreviation":"Proc Natl Acad Sci U S A","issue":"51","preprint":false}],"dataset_size":"2.1 TB","experiment_type":"EMDB","scale":"molecule","related_pdb_entries":["9bz8"],"entry_doi":"10.6019/EMPIAR-12631"}}