{"EMPIAR-12625":{"imagesets":[{"segmentations":[],"name":"Processed Tomograms of Vesicles containing Lipoprotein Lipase Filaments","directory":"data","category":"stitched maps","header_format":"MRC","data_format":"MRC","num_images_or_tilt_series":19,"frames_per_image":41,"frame_range_min":1,"frame_range_max":41,"voxel_type":"16 BIT FLOAT","pixel_width":7.86,"pixel_height":7.86,"micrographs_file_pattern":"","picked_particles_file_pattern":"","picked_particles_directory":"","details":"These are the reconstructed tomograms containing gold labeled vesicles from a lipoprotein lipase (LPL) secretory vesicle data set. The tomograms were reconstructed in IMOD, binned 4 times, denoised using topaz, and corrected using IsoNet. The gold labeled vesicles were subsequently analyzed for the presence of LPL filaments.","image_width":"1024","image_height":"1024"}],"workflow_file":null,"grant_references":[{"funding_body":"National Institutes of Health/National Heart, Lung, and Blood Institute (NIH/NHLBI)","code":"R01HL125654","country":"United States"},{"funding_body":"National Institutes of Health/National Heart, Lung, and Blood Institute (NIH/NHLBI)","code":"R01HL163352","country":"United States"},{"funding_body":"National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS)","code":"R00GM146024-04","country":"United States"}],"version_history":[],"title":"Cryogenic electron tomography reveals helical organization of lipoprotein lipase in storage vesicles","principal_investigator":[{"author_orcid":"0000-0003-4165-6674","middle_name":"B","organization":"Department of Biochemistry and Biophysics, UNC Chapel Hill","street":"120 Mason Farm Road","town_or_city":"Chapel Hill","state_or_province":"North Carolina","post_or_zip":"27599","telephone":"919-966-9550","fax":null,"first_name":"Saskia","last_name":"Neher","email":"neher [at] email.unc.edu","country":"United States","entry":"EMPIAR-12625"}],"status":"REL","deposition_date":"2025-03-13","release_date":"2025-12-07","obsolete_date":null,"update_date":"2025-12-07","corresponding_author":{"author":{"author_orcid":"0000-0003-2078-6947","middle_name":"H","organization":"Department of Biochemistry and Cell Biology, Stony Brook University","street":"450 Life Sciences Building","town_or_city":"Stony Brook","state_or_province":"New York","post_or_zip":"11790","first_name":"Kathryn","last_name":"Gunn","country":"United States"}},"authors":[{"author":{"name":"Gunn KH","author_orcid":"0000-0003-2078-6947"}},{"author":{"name":"Wheless A","author_orcid":"0000-0002-2549-8621"}},{"author":{"name":"Neher SB","author_orcid":"0000-0003-4165-6674"}}],"cross_references":["EMD-49737"],"biostudies_references":[],"idr_references":[],"empiar_references":[],"citation":[{"authors":[{"name":"Gunn KH","author_orcid":"0000-0003-2078-6947"},{"name":"Wheless A","author_orcid":"0000-0002-2549-8621"},{"name":"Calcraft T","author_orcid":null},{"name":"Kreutzberger M","author_orcid":null},{"name":"El-Houshy K","author_orcid":null},{"name":"Egelman EH","author_orcid":null},{"name":"Rosenthal PB","author_orcid":null},{"name":"Neher SB","author_orcid":"0000-0003-4165-6674"}],"editors":[],"published":false,"j_or_nj_citation":true,"title":"Cryogenic electron tomography reveals helical organization of lipoprotein lipase in storage vesicles","volume":null,"country":"","first_page":null,"last_page":null,"year":null,"language":null,"doi":null,"pubmedid":null,"details":null,"book_chapter_title":null,"publisher":null,"publication_location":null,"journal":"","journal_abbreviation":"","issue":null,"preprint":false}],"dataset_size":"10.8 GB","experiment_type":"EMDB","scale":"cell","entry_doi":"10.6019/EMPIAR-12625"}}