{"EMPIAR-12527":{"imagesets":[{"segmentations":[],"name":"Unaligned multi-frame of human Calpain-3","directory":"data/rawdata","category":"micrographs - multiframe","header_format":"TIFF","data_format":"TIFF","num_images_or_tilt_series":6054,"frames_per_image":60,"frame_range_min":null,"frame_range_max":null,"voxel_type":"UNSIGNED BYTE","pixel_width":0.413,"pixel_height":0.413,"micrographs_file_pattern":"","picked_particles_file_pattern":"","picked_particles_directory":"","details":"","image_width":null,"image_height":null}],"workflow_file":null,"grant_references":[],"version_history":[],"title":"Human calpain-3 forms a homohexamer","principal_investigator":[{"author_orcid":"0000-0002-9398-2941","middle_name":null,"organization":"UCSC Biomolecular cryoEM facility","street":"1156 High St","town_or_city":"Santa Cruz","state_or_province":"California","post_or_zip":"95060","telephone":null,"fax":null,"first_name":"Vitor Hugo","last_name":"Serrão","email":"vbalasco [at] ucsc.edu","country":"United States","entry":"EMPIAR-12527"}],"status":"REL","deposition_date":"2025-01-02","release_date":"2025-10-07","obsolete_date":null,"update_date":"2025-10-07","corresponding_author":{"author":{"author_orcid":"0000-0002-9398-2941","middle_name":null,"organization":"UCSC Biomolecular cryoEM facility","street":"1156 High St","town_or_city":"Santa Cruz","state_or_province":"California","post_or_zip":"95060","first_name":"Vitor Hugo","last_name":"Serrão","country":"United States"}},"authors":[{"author":{"name":"Ye Q","author_orcid":"0000-0002-5757-9514"}},{"author":{"name":"Balasco Serrão VH","author_orcid":"0000-0002-9398-2941"}},{"author":{"name":"Davies PL","author_orcid":"0000-0002-8026-7818"}}],"cross_references":["EMD-43646"],"biostudies_references":[],"idr_references":[],"empiar_references":[],"citation":[{"authors":[{"name":"Ye Q","author_orcid":"0000-0002-5757-9514"},{"name":"Balasco Serrão VH","author_orcid":"0000-0002-9398-2941"},{"name":"Davies PL","author_orcid":"0000-0002-8026-7818"}],"editors":[],"published":true,"j_or_nj_citation":true,"title":"Human calpain-3 and its structural plasticity: dissociation of a homohexamer into dimers on binding titin","volume":null,"country":"","first_page":null,"last_page":null,"year":"2024","language":"English","doi":"10.1016/j.jbc.2024.108133","pubmedid":"39725035","details":"Calpain-3 dataset: detector was used in super-resolution counting mode at a nominal magnification of 105,000x which produced a final pixel size of 0.413 Å. The total dose was 60 e-/Å2, over 60 frames with a nominal defocus range from -0.8 to -3.2 μm","book_chapter_title":null,"publisher":null,"publication_location":null,"journal":"The Journal of biological chemistry","journal_abbreviation":"J Biol Chem","issue":null,"preprint":false}],"dataset_size":"48.3 TB","experiment_type":"EMDB","scale":"molecule","entry_doi":"10.6019/EMPIAR-12527"}}