{"EMPIAR-12503":{"imagesets":[{"segmentations":[],"name":"Unaligned multi-frame raw data","directory":"data","category":"micrographs - multiframe","header_format":"MRC","data_format":"TIFF","num_images_or_tilt_series":5130,"frames_per_image":40,"frame_range_min":null,"frame_range_max":null,"voxel_type":"UNSIGNED BYTE","pixel_width":0.5325,"pixel_height":0.5325,"micrographs_file_pattern":"","picked_particles_file_pattern":"","picked_particles_directory":"","details":"Total dose: 50 electrons per square angstrom. Gain image included as a mrc file.","image_width":"11520","image_height":"8184"}],"workflow_file":null,"grant_references":[{"funding_body":"National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS)","code":"R35GM147179","country":"United States"}],"version_history":[],"title":"Cryo-EM Structure of the IFN-lambda4/IFN-lambdaR1/IL-10Rbeta receptor complex with an engineered IL-10Rbeta","principal_investigator":[{"author_orcid":"0000-0001-5832-6060","middle_name":null,"organization":"Department of Biochemistry and Molecular Biology, The University of Chicago","street":"929 E 57th Street, W201","town_or_city":"Chicago","state_or_province":"IL","post_or_zip":"60637","telephone":null,"fax":null,"first_name":"Minglei","last_name":"Zhao","email":"mlzhao [at] uchicago.edu","country":"United States","entry":"EMPIAR-12503"}],"status":"REL","deposition_date":"2024-12-05","release_date":"2026-05-20","obsolete_date":null,"update_date":"2026-05-20","corresponding_author":{"author":{"author_orcid":"0000-0001-5832-6060","middle_name":null,"organization":"Department of Biochemistry and Molecular Biology, The University of Chicago","street":"929 E 57th Street, W201","town_or_city":"Chicago","state_or_province":"IL","post_or_zip":"60637","first_name":"Minglei","last_name":"Zhao","country":"United States"}},"authors":[{"author":{"name":"Zhang B","author_orcid":"0000-0002-4907-3062"}},{"author":{"name":"Grubbe WS","author_orcid":"0000-0002-4933-2626"}},{"author":{"name":"Mendoza JL","author_orcid":"0000-0001-6972-7476"}},{"author":{"name":"Zhao M","author_orcid":"0000-0001-5832-6060"}}],"cross_references":["EMD-44790"],"biostudies_references":[],"idr_references":[],"empiar_references":[],"citation":[{"authors":[{"name":"Grubbe WS","author_orcid":"0000-0002-4933-2626"},{"name":"Zhang B","author_orcid":null},{"name":"Kauffman A","author_orcid":"0009-0004-0474-7758"},{"name":"Byléhn F","author_orcid":"0000-0001-9331-6773"},{"name":"Padoł K","author_orcid":null},{"name":"Jung HG","author_orcid":null},{"name":"Park SB","author_orcid":"0000-0003-2834-9071"},{"name":"Priest JM","author_orcid":"0000-0001-7511-6284"},{"name":"Özkan E","author_orcid":"0000-0002-0263-6729"},{"name":"de Pablo JJ","author_orcid":"0000-0002-3526-516X"},{"name":"Liang TJ","author_orcid":"0000-0003-3828-702X"},{"name":"Zhao M","author_orcid":"0000-0001-5832-6060"},{"name":"Mendoza JL","author_orcid":"0000-0001-6972-7476"}],"editors":[],"published":true,"j_or_nj_citation":true,"title":"Structural studies of the IFNλ4 receptor complex using cryoEM enabled by protein engineering","volume":"16","country":"United States","first_page":null,"last_page":null,"year":"2025","language":"English","doi":"10.1038/s41467-025-56119-y","pubmedid":"39827213","details":"The micrographs are multi-frame, unaligned movies in tiff format.","book_chapter_title":null,"publisher":null,"publication_location":null,"journal":"Nature communications","journal_abbreviation":"Nat Commun","issue":"1","preprint":false}],"dataset_size":"2.9 TB","experiment_type":"EMDB","scale":"molecule","related_pdb_entries":["9bpu"],"entry_doi":"10.6019/EMPIAR-12503"}}