{"EMPIAR-12432":{"imagesets":[{"segmentations":[],"name":"Cryo-EM movies of Coxsackievirus A9 bound with compound 18","directory":"data","category":"micrographs - multiframe","header_format":"MRC","data_format":"MRC","num_images_or_tilt_series":625,"frames_per_image":40,"frame_range_min":null,"frame_range_max":null,"voxel_type":"SIGNED 16 BIT INTEGER","pixel_width":0.97,"pixel_height":0.97,"micrographs_file_pattern":"data/Compound_18_CL304/FoilHole_*.mrc","picked_particles_file_pattern":"","picked_particles_directory":"","details":"Unprocessed micrographs (CVA9 with compound 18) from 200 kV FEI Talos Arctica TEM at 150kx nominal magnification. Electron dose of 40 electrons per square angstrom. Spherical abberation of 1.72 mm. Defocus range of -0.6 to -2.3 um.","image_width":"4096","image_height":"4096"}],"workflow_file":null,"grant_references":[{"funding_body":"Jane and Aatos Erkko Foundation","code":"210034","country":"Finland"},{"funding_body":"Academy of Finland","code":"315950","country":"Finland"},{"funding_body":"Sigrid Juselius Foundation","code":"95-7202-38","country":"Finland"}],"version_history":[],"title":"Cryo electron micrographs of Coxsackievirus A9 bound with compound 18 (CL304)","principal_investigator":[{"author_orcid":"0000-0001-7060-5871","middle_name":"Jane","organization":"University of Helsinki, Faculty of Biological and Environmental Sciences, MIBS, HiLIFE","street":"Viikinkaari 9","town_or_city":"Helsinki","state_or_province":"Uusimaa","post_or_zip":"00790","telephone":null,"fax":null,"first_name":"Sarah","last_name":"Butcher","email":"sarah.butcher [at] helsinki.fi","country":"Finland","entry":"EMPIAR-12432"},{"author_orcid":"0000-0002-4592-5926","middle_name":null,"organization":"University of Jyvaskyla, Faculty of Mathematics and Science","street":"Survontie 9","town_or_city":"Jyvaskyla","state_or_province":"Central Finland","post_or_zip":"40500","telephone":null,"fax":null,"first_name":"Varpu","last_name":"Marjomaki","email":"varpu.s.marjomaki [at] jyu.fi","country":"Finland","entry":"EMPIAR-12432"},{"author_orcid":"0000-0001-7466-8861","middle_name":null,"organization":"Sapienza University of Rome","street":"Piazzale Aldo Moro 5","town_or_city":"Rome","state_or_province":"Rome","post_or_zip":"00185","telephone":null,"fax":null,"first_name":"Giovanna","last_name":"Poce","email":"giovanna.poce [at] uniroma1.it","country":"Italy","entry":"EMPIAR-12432"}],"status":"REL","deposition_date":"2024-11-11","release_date":"2024-12-04","obsolete_date":null,"update_date":"2024-12-04","corresponding_author":{"author":{"author_orcid":"0009-0009-7679-0700","middle_name":null,"organization":"University of Helsinki","street":"Viikinkaari 9","town_or_city":"Helsinki","state_or_province":"Uusimaa","post_or_zip":"00790","first_name":"Cristopher","last_name":"Mitchell","country":"Finland"}},"authors":[{"author":{"name":"Plavec Z","author_orcid":"0000-0002-3335-3369"}},{"author":{"name":"Mitchell C","author_orcid":"0009-0009-7679-0700"}},{"author":{"name":"Buckner C","author_orcid":null}},{"author":{"name":"Butcher SJ","author_orcid":"0000-0001-7060-5871"}}],"cross_references":["EMD-50414"],"biostudies_references":[],"idr_references":[],"empiar_references":[],"citation":[{"authors":[{"name":"Tammaro C","author_orcid":null},{"name":"Plavec Z","author_orcid":null},{"name":"Myllymäki L","author_orcid":"0009-0004-0656-2570"},{"name":"Mitchell C","author_orcid":"0009-0009-7679-0700"},{"name":"Consalvi S","author_orcid":null},{"name":"Biava M","author_orcid":null},{"name":"Ciogli A","author_orcid":"0000-0002-7538-2424"},{"name":"Domanska A","author_orcid":"0000-0002-3772-6003"},{"name":"Leppilampi V","author_orcid":null},{"name":"Buckner C","author_orcid":null},{"name":"Manetto S","author_orcid":null},{"name":"Sciò P","author_orcid":null},{"name":"Coluccia A","author_orcid":"0000-0002-7940-8206"},{"name":"Laajala M","author_orcid":"0000-0003-3981-280X"},{"name":"Dondio GM","author_orcid":"0000-0001-5023-3804"},{"name":"Bigogno C","author_orcid":null},{"name":"Marjomäki V","author_orcid":"0000-0002-4592-5926"},{"name":"Butcher SJ","author_orcid":"0000-0001-7060-5871"},{"name":"Poce G","author_orcid":"0000-0001-7466-8861"}],"editors":[],"published":true,"j_or_nj_citation":true,"title":"SAR Analysis of Novel Coxsackie virus A9 Capsid Binders","volume":"67","country":"United States","first_page":"17144","last_page":"17161","year":"2024","language":"English","doi":"10.1021/acs.jmedchem.4c00701","pubmedid":"39292620","details":"Unprocessed micrographs from a 40 frame movie stack resulting in total 40 e-/Å exposure dose. Micrographs were collected on FEI Talos Arctica at * 150 000 nominal magnification.","book_chapter_title":null,"publisher":null,"publication_location":null,"journal":"Journal of medicinal chemistry","journal_abbreviation":"J Med Chem","issue":"19","preprint":false}],"dataset_size":"781.3 GB","experiment_type":"EMDB","scale":"virus","related_pdb_entries":["9fgn"],"entry_doi":"10.6019/EMPIAR-12432"}}