{"EMPIAR-12314":{"imagesets":[{"segmentations":[],"name":"unaligned 40-frame movies, 0.53A/px, 40e/movie","directory":"data","category":"micrographs - multiframe","header_format":"TIFF","data_format":"TIFF","num_images_or_tilt_series":6244,"frames_per_image":40,"frame_range_min":1,"frame_range_max":40,"voxel_type":"UNSIGNED BYTE","pixel_width":1.6,"pixel_height":1.6,"micrographs_file_pattern":"data/BenzR1_2_00004_X+1Y+0-2.tif","picked_particles_file_pattern":"","picked_particles_directory":"","details":"","image_width":"11520","image_height":"8184"}],"workflow_file":null,"grant_references":[{"funding_body":"National Science Foundation (NSF, United States)","code":"2203613","country":"United States"}],"version_history":[],"title":"EcPKS2 with acylated pPANT and three ACP-docked positions","principal_investigator":[{"author_orcid":"0000-0001-6796-7740","middle_name":null,"organization":"University of Utah, Department of Biochemistry","street":"15 N Medical Drive East","town_or_city":"Salt Lake City","state_or_province":"Utah","post_or_zip":"84112","telephone":"801-792-7765","fax":"+1 801 581 7959","first_name":"Christopher","last_name":"Hill","email":"heidi [at] biochem.utah.edu","country":"United States","entry":"EMPIAR-12314"}],"status":"REL","deposition_date":"2024-08-28","release_date":"2025-02-11","obsolete_date":null,"update_date":"2025-02-11","corresponding_author":{"author":{"author_orcid":"0000-0003-1762-8390","middle_name":"Linda","organization":"Department of Biochemistry; University of Utah","street":"15 N Medical Drive South","town_or_city":"Salt Lake City","state_or_province":"Utah","post_or_zip":"84112","first_name":"Heidi","last_name":"Schubert","country":"United States"}},"authors":[{"author":{"name":"Schubert HL","author_orcid":"0000-0003-1762-8390"}}],"cross_references":["EMD-45913","EMD-45912","EMD-45911"],"biostudies_references":[],"idr_references":[],"empiar_references":[],"citation":[{"authors":[{"name":"Schubert HL","author_orcid":"0000-0003-1762-8390"},{"name":"Li F","author_orcid":null},{"name":"Hill CP","author_orcid":"0000-0001-6796-7740"},{"name":"Schmidt EW","author_orcid":"0000-0001-5839-694X"}],"editors":[],"published":true,"j_or_nj_citation":true,"title":"The structure of full-length AFPK supports the ACP linker in a role that regulates iterative polyketide and fatty acid assembly","volume":"122","country":"United States","first_page":null,"last_page":null,"year":"2025","language":"English","doi":"10.1073/pnas.2419884122","pubmedid":"39913209","details":"The micrographs are EcPKS2 bound to acylated pPANT on the ACP domain and with a acyl-group bound to the b-KetoSynthase domain active site Cys. ACP is docked to the DH domain and partially at the KS domain.","book_chapter_title":null,"publisher":null,"publication_location":null,"journal":"Proceedings of the National Academy of Sciences of the United States of America","journal_abbreviation":"Proc Natl Acad Sci U S A","issue":"6","preprint":false}],"dataset_size":"2.9 TB","experiment_type":"EMDB","scale":"molecule","related_pdb_entries":["9cto","9ctn","9ctm"],"entry_doi":"10.6019/EMPIAR-12314"}}