{"EMPIAR-12312":{"imagesets":[{"segmentations":[],"name":"Unaligned multi-frame movies of recombinant PNMA2","directory":"data/Images-Disc1","category":"micrographs - multiframe","header_format":"TIFF","data_format":"TIFF","num_images_or_tilt_series":17600,"frames_per_image":24,"frame_range_min":null,"frame_range_max":null,"voxel_type":"UNSIGNED 16 BIT INTEGER","pixel_width":0.6788,"pixel_height":0.6788,"micrographs_file_pattern":"data/Images-Disc1/GridSquare_*/Data/FoilHole_*_Data_*_*_*_*_fractions.tiff","picked_particles_file_pattern":"data/particles.star","picked_particles_directory":"","details":"Unaligned, non-gain-normalised, 24-frame movies from a Bioquantum-K3 camera recorded in super-resolution mode with twofold binning at 130,000x magnification with EPU on the MIT.nano Titan Krios G3i at 300keV. Please apply \"gainref.mrc\" during motion correction. This can be used as is for cryosparc, and with \"Flip upside down (1)\" in RELION. \"particles.star\" contains the final picked particles in EMD-42812","image_width":"5760","image_height":"4092"}],"workflow_file":null,"grant_references":[{"funding_body":"Howard Hughes Medical Institute (HHMI)","code":"NA","country":"United States"},{"funding_body":"National Institutes of Health/National Heart, Lung, and Blood Institute (NIH/NHLBI)","code":"R01HG009761","country":"United States"}],"version_history":[],"title":"Cryo-EM micrographs for a recombinant human PNMA2 capsid","principal_investigator":[{"author_orcid":"0000-0003-0178-7995","middle_name":null,"organization":"Broad Institute of MIT and Harvard","street":null,"town_or_city":"Cambridge","state_or_province":null,"post_or_zip":"02142","telephone":null,"fax":null,"first_name":"Feng","last_name":"Zhang","email":"zhang [at] broadinstitute.org","country":"United States","entry":"EMPIAR-12312"}],"status":"REL","deposition_date":"2024-03-28","release_date":"2025-04-24","obsolete_date":null,"update_date":"2025-04-24","corresponding_author":{"author":{"author_orcid":"0000-0003-4738-9503","middle_name":null,"organization":"Broad Institute of MIT and Harvard","street":"75 Ames St","town_or_city":"Cambridge","state_or_province":"Massachusetts","post_or_zip":"02142","first_name":"Max","last_name":"Wilkinson","country":"United States"}},"authors":[{"author":{"name":"Madigan V","author_orcid":null}},{"author":{"name":"Zhang Y","author_orcid":"0000-0002-1141-5821"}},{"author":{"name":"Raghavan R","author_orcid":null}},{"author":{"name":"Wilkinson ME","author_orcid":"0000-0003-4738-9503"}},{"author":{"name":"Faure G","author_orcid":"0000-0001-9537-2277"}},{"author":{"name":"Puccio E","author_orcid":null}},{"author":{"name":"Segel M","author_orcid":null}},{"author":{"name":"Lash B","author_orcid":null}},{"author":{"name":"Macrae RK","author_orcid":"0000-0002-7850-9056"}},{"author":{"name":"Zhang F","author_orcid":"0000-0002-7444-1103"}}],"cross_references":["EMD-42812"],"biostudies_references":[],"idr_references":[],"empiar_references":[],"citation":[{"authors":[{"name":"Madigan V","author_orcid":null},{"name":"Zhang Y","author_orcid":"0000-0002-1141-5821"},{"name":"Raghavan R","author_orcid":null},{"name":"Wilkinson ME","author_orcid":"0000-0003-4738-9503"},{"name":"Faure G","author_orcid":"0000-0001-9537-2277"},{"name":"Puccio E","author_orcid":null},{"name":"Segel M","author_orcid":null},{"name":"Lash B","author_orcid":null},{"name":"Macrae RK","author_orcid":"0000-0002-7850-9056"},{"name":"Zhang F","author_orcid":"0000-0002-7444-1103"}],"editors":[],"published":true,"j_or_nj_citation":true,"title":"Human paraneoplastic antigen Ma2 (PNMA2) forms icosahedral capsids that can be engineered for mRNA delivery","volume":"121","country":"","first_page":"e2307812120","last_page":"308","year":"2024","language":"English","doi":"10.1073/pnas.2307812120","pubmedid":"38437549","details":null,"book_chapter_title":null,"publisher":null,"publication_location":null,"journal":"Proceedings of the National Academy of Sciences of the United States of America","journal_abbreviation":"Proc Natl Acad Sci U S A","issue":"11","preprint":false}],"dataset_size":"1.8 TB","experiment_type":"EMDB","scale":"molecule","related_pdb_entries":["8uyo"],"entry_doi":"10.6019/EMPIAR-12312"}}