{"EMPIAR-12289":{"imagesets":[{"segmentations":[],"name":"Multi-frame cryo-EM images of a 69 kDa KRAS:G12C-2H11.4DS Fab complex in tiff format","directory":"data/230320_KRas_Krios2_grid_005972_session_002335/data","category":"micrographs - multiframe","header_format":"TIFF","data_format":"TIFF","num_images_or_tilt_series":5013,"frames_per_image":119,"frame_range_min":null,"frame_range_max":null,"voxel_type":"UNSIGNED BYTE","pixel_width":0.838,"pixel_height":0.838,"micrographs_file_pattern":"data/230320_KRas_Krios2_grid_005972_session_002335/data/*.tif","picked_particles_file_pattern":"","picked_particles_directory":"","details":"Multi-frame cryo-EM images of a 69 kDa KRAS:G12C-2H11.4DS Fab complex in tiff format.\n\nGain file: CountCDSRef_movie_77-1_000_Mar20_18.55.42_1-0.mrc\nPixel spacing: 0.838Å\nTotal dose per image: 68.277 electrons/Ų\nFrames per image: 119\nObjective aperture diameter: 100μm\nC2 aperture diameter: 50μm\nGun lens setting: 4\nEnergy filter slit width: 20eV","image_width":"5760","image_height":"4092"}],"workflow_file":null,"grant_references":[],"version_history":[],"title":"Multi-frame cryo-EM images of a 69 kDa KRAS:G12C-2H11.4DS Fab complex","principal_investigator":[{"author_orcid":"0000-0003-0737-2299","middle_name":null,"organization":"Genentech","street":"DNA Way","town_or_city":"South San Francisco","state_or_province":"California","post_or_zip":"94080","telephone":null,"fax":null,"first_name":"Jawahar","last_name":"Sudhamsu","email":"jawahars [at] gene.com","country":"United States","entry":"EMPIAR-12289"},{"author_orcid":"0000-0002-3343-9621","middle_name":null,"organization":"Genentech","street":null,"town_or_city":"South San Francisco","state_or_province":null,"post_or_zip":"94080","telephone":null,"fax":null,"first_name":"Alexis","last_name":"Rohou","email":"rohoua [at] gene.com","country":"United States","entry":"EMPIAR-12289"},{"author_orcid":"0000-0001-7019-3221","middle_name":null,"organization":"Genentech","street":"DNA Way","town_or_city":"South San Francisco","state_or_province":"California","post_or_zip":"94080","telephone":null,"fax":null,"first_name":"Dimitry","last_name":"Tegunov","email":"tegunovd [at] gene.com","country":"United States","entry":"EMPIAR-12289"}],"status":"REL","deposition_date":"2024-05-16","release_date":"2025-07-16","obsolete_date":null,"update_date":"2025-07-16","corresponding_author":{"author":{"author_orcid":"0000-0002-3343-9621","middle_name":null,"organization":"Genentech","street":"DNA Way","town_or_city":"South San Francisco","state_or_province":"California","post_or_zip":"94080","first_name":"Alexis","last_name":"Rohou","country":"United States"}},"authors":[{"author":{"name":"Kung JE","author_orcid":"0000-0002-6784-7076"}},{"author":{"name":"Caleigh A","author_orcid":"0000-0002-3484-9921"}}],"cross_references":["EMD-43221"],"biostudies_references":[],"idr_references":[],"empiar_references":[],"citation":[{"authors":[{"name":"Kung JE","author_orcid":"0000-0002-6784-7076"},{"name":"Johnson MC","author_orcid":"0000-0002-1477-7801"},{"name":"Jao CC","author_orcid":"0009-0003-2597-8937"},{"name":"Arthur CP","author_orcid":null},{"name":"Tegunov D","author_orcid":"0000-0001-7019-3221"},{"name":"Rohou A","author_orcid":"0000-0002-3343-9621"},{"name":"Sudhamsu J","author_orcid":"0000-0003-0737-2299"}],"editors":[],"published":true,"j_or_nj_citation":true,"title":"Disulfide constrained Fabs overcome target size limitation for high-resolution single-particle cryo-EM","volume":null,"country":"","first_page":null,"last_page":null,"year":"2024","language":"English","doi":"10.1101/2024.05.10.593593","pubmedid":null,"details":"Multi-frame cryo-EM images of a 69 kDa KRAS:G12C-2H11.4DS Fab complex in tiff format.\n\nGain file: CountCDSRef_movie_77-1_000_Mar20_18.55.42_1-0.mrc\nPixel spacing: 0.838Å\nTotal dose per image: 68.277 electrons/Ų\nFrames per image: 119\nObjective aperture diameter: 100μm\nC2 aperture diameter: 50μm\nGun lens setting: 4\nEnergy filter slit width: 20eV","book_chapter_title":null,"publisher":null,"publication_location":null,"journal":"bioRxiv","journal_abbreviation":"","issue":null,"preprint":true}],"dataset_size":"1.9 TB","experiment_type":"EMDB","scale":"molecule","related_pdb_entries":["8vgq"],"entry_doi":"10.6019/EMPIAR-12289"}}