{"EMPIAR-12217":{"imagesets":[{"segmentations":[],"name":"Unaligned multiframe micrographs of ATTRwt amyloid fibrils","directory":"data/ATTRwt_raw_data","category":"micrographs - multiframe","header_format":"TIFF","data_format":"TIFF","num_images_or_tilt_series":1943,"frames_per_image":40,"frame_range_min":null,"frame_range_max":null,"voxel_type":"UNSIGNED 16 BIT INTEGER","pixel_width":1.04,"pixel_height":1.04,"micrographs_file_pattern":"data/ATTRwt_raw_data/map_????_???.tif","picked_particles_file_pattern":"","picked_particles_directory":"","details":"Krios1 Quantum-K2\nCs 2.7\n300kV EFTEM nanpprobe\nx130k spot 8 beam size 620nm\nc2=50  objective_aperture=100\n\nGIF-K2 counting\n12s exposure 40 frames\ntotal dose at the sample 44.90e/A2\n1 pixel = 1.04A\ndose rate ~3 e/pix/s\ndefocus range -1.2 to -2.5","image_width":"3838","image_height":"3710"}],"workflow_file":null,"grant_references":[],"version_history":[],"title":"Wild type ATTR amyloid fibril from senile systemic amyloidosis","principal_investigator":[{"author_orcid":"0000-0002-9442-460X","middle_name":null,"organization":"Institut für Proteinbiochemie, Universität Ulm","street":null,"town_or_city":"Ulm","state_or_province":null,"post_or_zip":"89081","telephone":null,"fax":null,"first_name":"Matthias","last_name":"Schmidt","email":"matthias.schmidt [at] uni-ulm.de","country":"Germany","entry":"EMPIAR-12217"},{"author_orcid":"0000-0003-2123-6816","middle_name":null,"organization":"Institut für Proteinbiochemie, Universität Ulm","street":"8/1 Helmholtzstrasse","town_or_city":"Ulm","state_or_province":"Baden Württemberg","post_or_zip":"89081","telephone":null,"fax":null,"first_name":"Marcus","last_name":"Fändrich","email":"marcus.faendrich [at] uni-ulm.de","country":"Germany","entry":"EMPIAR-12217"}],"status":"REL","deposition_date":"2024-08-06","release_date":"2025-02-04","obsolete_date":null,"update_date":"2025-02-04","corresponding_author":{"author":{"author_orcid":"0000-0002-9442-460X","middle_name":null,"organization":"Institut für Proteinbiochemie, Universität Ulm","street":"8/1 Helmholtzstrasse","town_or_city":"Ulm","state_or_province":"Baden Württemberg","post_or_zip":"89081","first_name":"Matthias","last_name":"Schmidt","country":"Germany"}},"authors":[{"author":{"name":"Steinebrei M","author_orcid":"0000-0002-0582-3909"}},{"author":{"name":"Schmidt M","author_orcid":"0000-0002-9442-460X"}},{"author":{"name":"Fändrich M","author_orcid":"0000-0003-2123-6816"}}],"cross_references":["EMD-15361"],"biostudies_references":[],"idr_references":[],"empiar_references":[],"citation":[{"authors":[{"name":"Steinebrei M","author_orcid":"0000-0002-0582-3909"},{"name":"Gottwald J","author_orcid":"0000-0001-6493-4900"},{"name":"Baur J","author_orcid":null},{"name":"Röcken C","author_orcid":"0000-0002-6989-8002"},{"name":"Hegenbart U","author_orcid":"0000-0003-1917-6746"},{"name":"Schönland S","author_orcid":"0000-0002-4853-5579"},{"name":"Schmidt M","author_orcid":"0000-0002-9442-460X"}],"editors":[],"published":true,"j_or_nj_citation":true,"title":"Cryo-EM structure of an ATTRwt amyloid fibril from systemic non-hereditary transthyretin amyloidosis","volume":"13","country":"","first_page":null,"last_page":null,"year":"2022","language":"English","doi":"10.1038/s41467-022-33591-4","pubmedid":"36302762","details":null,"book_chapter_title":null,"publisher":null,"publication_location":null,"journal":"Nature communications","journal_abbreviation":"Nat Commun","issue":"1","preprint":false}],"dataset_size":"332.2 GB","experiment_type":"EMDB","scale":"molecule","related_pdb_entries":["8ade"],"entry_doi":"10.6019/EMPIAR-12217"}}