{"EMPIAR-12182":{"imagesets":[{"segmentations":[],"name":"Raw and processed data","directory":"data","category":"micrographs - multiframe","header_format":"TIFF","data_format":"TIFF","num_images_or_tilt_series":7235,"frames_per_image":60,"frame_range_min":null,"frame_range_max":null,"voxel_type":"UNSIGNED BYTE","pixel_width":null,"pixel_height":null,"micrographs_file_pattern":"","picked_particles_file_pattern":"","picked_particles_directory":"","details":"Raw and processed data collected at Krios G3i, 300 kV, 32.26 e/A2 using Gatan K3 Biocontinuum.","image_width":"11520","image_height":"8184"}],"workflow_file":null,"grant_references":[{"funding_body":"National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID)","code":"R01 AI144090","country":"United States"}],"version_history":[],"title":"Single particle cryoelectron microscopy of Human astrovirus 1 spike in complex with neutralizing Fabs 3B4 and 3H4","principal_investigator":[{"author_orcid":"0000-0003-4185-5673","middle_name":"M","organization":"Biomolecular Engineering Department","street":"1156 High St","town_or_city":"Santa Cruz","state_or_province":"CA","post_or_zip":"95060","telephone":null,"fax":null,"first_name":"Rebecca","last_name":"DuBois","email":"rmdubois [at] ucsc.edu","country":"United States","entry":"EMPIAR-12182"}],"status":"REL","deposition_date":"2024-06-18","release_date":"2025-10-10","obsolete_date":null,"update_date":"2025-10-10","corresponding_author":{"author":{"author_orcid":"0000-0002-9398-2941","middle_name":null,"organization":"UCSC Biomolecular cryoEM facility","street":"1156 High St","town_or_city":"Santa Cruz","state_or_province":"California","post_or_zip":"95060","first_name":"Vitor Hugo","last_name":"Serrão","country":"United States"}},"authors":[{"author":{"name":"Lanning S","author_orcid":"0000-0002-6206-2843"}},{"author":{"name":"Balasco Serrao VH","author_orcid":"0000-0002-9398-2941"}},{"author":{"name":"DuBois RM","author_orcid":"0000-0003-4185-5673"}}],"cross_references":["EMD-45427"],"biostudies_references":[],"idr_references":[],"empiar_references":[],"citation":[{"authors":[{"name":"Lanning S","author_orcid":"0000-0002-6206-2843"},{"name":"Aguilar-Hernández N","author_orcid":null},{"name":"Serrão VHB","author_orcid":"0000-0002-9398-2941"},{"name":"López T","author_orcid":null},{"name":"O'Rourke SM","author_orcid":null},{"name":"Lentz A","author_orcid":"0009-0004-2628-3712"},{"name":"Ricemeyer L","author_orcid":"0000-0001-5543-6117"},{"name":"Espinosa R","author_orcid":null},{"name":"López S","author_orcid":"0000-0001-6336-9209"},{"name":"Arias CF","author_orcid":"0000-0003-3130-4501"},{"name":"DuBois RM","author_orcid":"0000-0003-4185-5673"}],"editors":[],"published":true,"j_or_nj_citation":true,"title":"Discovery of three novel neutralizing antibody epitopes on the human astrovirus capsid spike and mechanistic insights into virus neutralization","volume":null,"country":"United States","first_page":null,"last_page":null,"year":"2025","language":"English","doi":"10.1128/jvi.01619-24","pubmedid":"39846739","details":"Raw data of Human astrovirus 1 spike in complex with neutralizing Fabs 3B4 and 3H4 collected at PNCC (160263) at 300 kV Krios (CS 2.7 nm) pixel size 0.415 A/pix and total dose of 50 e/A2. Processed data using cryoSPARC workflow.","book_chapter_title":null,"publisher":null,"publication_location":null,"journal":"Journal of virology","journal_abbreviation":"J Virol","issue":null,"preprint":false}],"dataset_size":"26.4 TB","experiment_type":"EMDB","scale":"molecule","related_pdb_entries":["9cbn"],"entry_doi":"10.6019/EMPIAR-12182"}}